117,177 research outputs found

    Applications of next-generation sequencing technologies and computational tools in molecular evolution and aquatic animals conservation studies : a short review

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    Aquatic ecosystems that form major biodiversity hotspots are critically threatened due to environmental and anthropogenic stressors. We believe that, in this genomic era, computational methods can be applied to promote aquatic biodiversity conservation by addressing questions related to the evolutionary history of aquatic organisms at the molecular level. However, huge amounts of genomics data generated can only be discerned through the use of bioinformatics. Here, we examine the applications of next-generation sequencing technologies and bioinformatics tools to study the molecular evolution of aquatic animals and discuss the current challenges and future perspectives of using bioinformatics toward aquatic animal conservation efforts

    Challenges of the next decade for the Asia Pacific region: 2010 International Conference in Bioinformatics (InCoB 2010)

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    The 2010 annual conference of the Asia Pacific Bioinformatics Network (APBioNet), Asia’s oldest bioinformatics organisation formed in 1998, was organized as the 9th International Conference on Bioinformatics (InCoB), Sept. 26-28, 2010 in Tokyo, Japan. Initially, APBioNet created InCoB as forum to foster bioinformatics in the Asia Pacific region. Given the growing importance of interdisciplinary research, InCoB2010 included topics targeting scientists in the fields of genomic medicine, immunology and chemoinformatics, supporting translational research. Peer-reviewed manuscripts that were accepted for publication in this supplement, represent key areas of research interests that have emerged in our region. We also highlight some of the current challenges bioinformatics is facing in the Asia Pacific region and conclude our report with the announcement of APBioNet’s 100 BioDatabases (BioDB100) initiative. BioDB100 will comply with the database criteria set out earlier in our proposal for Minimum Information about a Bioinformatics and Investigation (MIABi), setting the standards for biocuration and bioinformatics research, on which we will report at the next InCoB, Nov. 27 – Dec. 2, 2011 at Kuala Lumpur, Malaysia

    Recent developments in life sciences research: Role of bioinformatics

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    Life sciences research and development has opened up new challenges and opportunities for bioinformatics. The contribution of bioinformatics advances made possible the mapping of the entire human genome and genomes of many other organisms in just over a decade. These discoveries, along with current efforts to determine gene and protein functions, have improved our ability to understand the root causes of human, animal and plant diseases and find new cures. Furthermore, many future Bioinformatic innovations will likely be spurred by the data and analysis demands of the life sciences. This review briefly describes the role of bioinformatics in biotechnology, drug discovery, biomarkerdiscovery, biological databases, bioinformatic tools, bioinformatic tasks and its application in life sciences research

    Commercialization of bioinformatics and biotechnology products in Malaysia: an overview

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    Commercialization of Research and Development (R&D) Products, particularly bioinformatics and biotechnology has always being overlooked by the industry and academic sectors. There are some misleading concepts that triggers both these sectors that commercialization of R&D products is not as part of their responsibilities. This is because the knowledge of R&D products emerges from academic world while commercialization involves business oriented field. This article is produced based on reference of various papers on commercialization of R&D products in Malaysia. Highlights of this article is to enlighten the current efforts and challenges faced by Malaysia in promoting R&D, specifically bioinformatics and biotechnology products, and produce thoughtful discussion in improving the current effort
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