Compensating mode conversion due to bend discontinuities through intentional trace asymmetry

In this letter, a comparative analysis is carried out between the mechanism of mode conversion in differential microstrip lines due to bend discontinuities on one side and trace asymmetry on the other side. With the help of equivalent modal circuits, a theoretical basis is provided for the idea to compensate the undesired common mode (CM), due to the presence of the bend, by intentionally designing asymmetric traces. As an application example, the proposed CM-reduction strategy is used in conjunction with another recently-presented wideband CM suppression filter for differential microstrip lines. It is shown that the proposed solution enhances the overall CM-reduction performance of the filter by some decibels, while preserving its transmission properties

The Peach RGF/GLV Signaling Peptide pCTG134 Is Involved in a Regulatory Circuit That Sustains Auxin and Ethylene Actions

In vascular plants the cell-to-cell interactions coordinating morphogenetic and physiological processes are mediated, among others, by the action of hormones, among which also short mobile peptides were recognized to have roles as signals. Such peptide hormones (PHs) are involved in defense responses, shoot and root growth, meristem homeostasis, organ abscission, nutrient signaling, hormone crosstalk and other developmental processes and act as both short and long distant ligands. In this work, the function of CTG134, a peach gene encoding a ROOT GROWTH FACTOR/GOLVEN-like PH expressed in mesocarp at the onset of ripening, was investigated for its role in mediating an auxin-ethylene crosstalk. In peach fruit, where an auxin-ethylene crosstalk mechanism is necessary to support climacteric ethylene synthesis, CTG134 expression peaked before that of ACS1 and was induced by auxin and 1-methylcyclopropene (1-MCP) treatments, whereas it was minimally affected by ethylene. In addition, the promoter of CTG134 fused with the GUS reporter highlighted activity in plant parts in which the auxin-ethylene interplay is known to occur. Arabidopsis and tobacco plants overexpressing CTG134 showed abnormal root hair growth, similar to wild-type plants treated with a synthetic form of the sulfated peptide. Moreover, in tobacco, lateral root emergence and capsule size were also affected. In Arabidopsis overexpressing lines, molecular surveys demonstrated an impaired hormonal crosstalk, resulting in a re-modulated expression of a set of genes involved in both ethylene and auxin synthesis, transport and perception. These data support the role of pCTG134 as a mediator in an auxin-ethylene regulatory circuit and open the possibility to exploit this class of ligands for the rational design of new and environmental friendly agrochemicals able to cope with a rapidly changing environment

Comprehensive and modular stochastic modeling framework for the variability-aware assessment of Signal Integrity in high-speed links

This paper presents a comprehensive and modular modeling framework for stochastic signal integrity analysis of complex high-speed links. Such systems are typically composed of passive linear networks and nonlinear, usually active, devices. The key idea of the proposed contribution is to express the signals at the ports of each of such system elements or subnetworks as a polynomial chaos expansion. This allows one to compute, for each block, equivalent deterministic models describing the stochastic variations of the network voltages and currents. Such models are synthesized into SPICE-compatible circuit equivalents, which are readily connected together and simulated in standard circuit simulators. Only a single circuit simulation of such an equivalent network is required to compute the pertinent statistical information of the entire system, without the need of running a large number of time-consuming electromagnetic circuit co-simulations. The accuracy and efficiency of the proposed approach, which is applicable to a large class of complex circuits, are verified by performing signal integrity investigations of two interconnect examples

Monitoring of Single-Cell Responses in the Optic Tectum of Adult Zebrafish with Dextran-Coupled Calcium Dyes Delivered via Local Electroporation

Kassing V, Engelmann J, Kurtz R. Monitoring of Single-Cell Responses in the Optic Tectum of Adult Zebrafish with Dextran-Coupled Calcium Dyes Delivered via Local Electroporation. PLoS ONE. 2013;8(5): e62846.The zebrafish (Danio rerio) has become one of the major animal models for in vivo examination of sensory and neuronal computation. Similar to Xenopus tadpoles neural activity in the optic tectum, the major region controlling visually guided behavior, can be examined in zebrafish larvae by optical imaging. Prerequisites of these approaches are usually the transparency of larvae up to a certain age and the use of two-photon microscopy. This principle of fluorescence excitation was necessary to suppress crosstalk between signals from individual neurons, which is a critical issue when using membrane-permeant dyes. This makes the equipment to study neuronal processing costly and limits the approach to the study of larvae. Thus there is lack of knowledge about the properties of neurons in the optic tectum of adult animals. We established a procedure to circumvent these problems, enabling in vivo calcium imaging in the optic tectum of adult zebrafish. Following local application of dextran-coupled dyes single-neuron activity of adult zebrafish can be monitored with conventional widefield microscopy, because dye labeling remains restricted to tens of neurons or less. Among the neurons characterized with our technique we found neurons that were selective for a certain pattern orientation as well as neurons that responded in a direction-selective way to visual motion. These findings are consistent with previous studies and indicate that the functional integrity of neuronal circuits in the optic tectum of adult zebrafish is preserved with our staining technique. Overall, our protocol for in vivo calcium imaging provides a useful approach to monitor visual responses of individual neurons in the optic tectum of adult zebrafish even when only widefield microscopy is available. This approach will help to obtain valuable insight into the principles of visual computation in adult vertebrates and thus complement previous work on developing visual circuits

A multiple scattering method to study the cable harness inside a vehicle shell

This dissertation contains three major parts. In the first part, a generalized multi-conductor transmission line (GMTL) method is proposed to model a cable harness. In the GMTL method, all wires of the cable harness take the infinity as the reference. In such a way, the GMTL method takes into account not only the transmission-line mode but also the antenna-mode current on the cable harness. Further, by employing the GMTL method and the mixed-potential integral equations (MPIE) method in a multiple scattering (MS) procedure, it enables an efficient and accurate approach to evaluate the current distribution on a cable harness with a nearby metal surface. Notice that the cable harness is not grounded to the metal surface in this part. In the second part, a hybrid algorithm called the generalized multiple scattering (GMS) method is proposed to efficiently and accurately calculate the current distribution on a cable harness which has several ground connections to a nearby metal surface. This is a simplified case to mimic a cable harness routed inside a vehicle shell. The GMS method uses the GMTL method for the cable harness part and the MPIE method for the rest of the structure including the metal surface and the grounding wires. Neither the GMTL nor the MPIE method alone takes into account the mutual interactions between the cable harness and the rest of the structure. Therefore, an iterative scheme is arranged in the GMS method to compensate the abovementioned interactions. These interactions occur via not only field couplings, but also current conducting through the grounding points on the cable harness. In the third part, the GMTL method is reformulated to cover both straight and bent cable harnesses. The extraction of the per-unit-length inductance and capacitance is also simplified compared to the extraction method described in the first part. Besides, the steepest descent method is utilized to compute the radiation of a cable harness based on the obtained current through the GMTL method. The capability and limitations of the GMTL method are also carefully examined --Abstract, page iv

Adaptive transient solution of nonuniform multiconductor transmission lines using wavelets

Abstract—This paper presents a highly adaptive algorithm for the transient simulation of nonuniform interconnects loaded with arbitrary nonlinear and dynamic terminations. The discretization of the governing equations is obtained through a weak formula-tion using biorthogonal wavelet bases as trial and test functions. It is shown how the multiresolution properties of wavelets lead to very sparse approximations of the voltages and currents in typical transient analyzes. A simple yet effective time–space adaptive al-gorithm capable of selecting the minimal number of unknowns at each time iteration is described. Numerical results show the high degree of adaptivity of the proposed scheme. Index Terms—Electromagnetic (EM) transient analysis, multi-conductor transmission lines (TLs), wavelet transforms. I

Common-mode noise reduction schemes for weakly coupled differential serpentine delay microstrip lines

This paper proposes design schemes to reduce the common mode noise from weakly coupled differential serpentine delay microstrip lines (DSDMLs). The proposed approach is twofold: we leverage strongly coupled vertical-turn-coupled traces (VTCTs) instead of weakly coupled VTCTs (conventional pattern) and add guard traces. Time- and frequency-domain analyses of the proposed schemes for reducing the common-mode noise are performed by studying the transmission waveform and the differential-to-common mode conversion using the circuit solver HSPICE and the 3-D full-wave simulator HFSS, respectively. Compared to the conventional design of the weakly coupled DSDMLs, the proposed solutions yield a reduction of about 54% of the peak-to-peak amplitude of the common-mode noise, while the differential impedance remains matched along the complete length of the DSDML. Moreover, the range of frequencies, over which the magnitude of the differential-to-common mode conversion is now significantly reduced, is very wide, i.e. about 0.3-10 GHz. Furthermore, the differential insertion and reflection loss introduced by the newly proposed designs are almost the same as the ones achieved by using the conventional design. Finally, a favorable comparison between simulated and measured results confirms the excellent common-mode noise reduction performance of the proposed schemes

Ring-resonator-based wavelength filters

Microring resonators (MR) represent a class of filters with characteristics very similar to those of Fabry–Perot filters. However, they offer the advantage that the injected and reflected signals are separated in individual waveguides, and in addition, their design does not require any facets or gratings and is thus particularly simple. MRs evolved from the fields of fibre optic ring resonators and micron scale droplets. Their inherently small size (with typical diameters in the range between several to tens of micrometres), their filter characteristics and their potential for being used in complex and flexible configurations make these devices particularly attractive for integrated optics or VLSI photonics applications.\ud MRs for filter applications, delay lines, as add/drop multiplexers, and modulators will be covered in detail in this chapter, while other applications such as in optical sensing, in spectroscopy or for coherent light generation (MR lasers) are outside the scope of this chapter.\ud This chapter focuses primarily on 4-port microrings, while 2-port devices will play a minor role here and are covered in more detail in Chap. 9. The present chapter starts with design considerations, the functional behaviour, and key characteristics of a single microring resonator and continues with the design of cascaded MRs allowing the implementation of higher order filters. Finally, complex devices like add-drop filters, tuneable dispersion compensators, all-optical wavelength converters, and tuneable cross-connects are treated.\u

Engineering evaluations and studies. Volume 3: Exhibit C

High rate multiplexes asymmetry and jitter, data-dependent amplitude variations, and transition density are discussed