Integrated inpection of sculptured surface products using machine vision and a coordinate measuring machine

In modem manufacturing technology with increasing automation of manufacturing processes and operations, the need for automated measurement has become much more apparent. Computer measuring machines are one of the essential instruments for quality control and measurement of complex products, performing measurements that were previously laborious and time consuming. Inspection of sculptured surfaces can be time consuming since, for exact specification, an almost infinite number of points would be required. Automated measurement with a significant reduction of inspected points can be attempted if prior knowledge of the part shape is available. The use of a vision system can help to identify product shape and features but, unfortunately, the accuracy required is often insufficient. In this work a vision system used with a Coordinate Measuring Machine (CMM), incorporating probing, has enabled fast and accurate measurements to be obtained. The part features have been enhanced by surface marking and a simple 2-D vision system has been utilised to identify part features. In order to accurately identify all parts of the product using the 2-D vision system, a multiple image superposition method has been developed which enables 100 per cent identification of surface features. A method has been developed to generate approximate 3-D surface position from prior knowledge of the product shape. A probing strategy has been developed which selects correct probe angle for optimum accuracy and access, together with methods and software for automated CMM code generation. This has enabled accurate measurement of product features with considerable reductions in inspection time. Several strategies for the determination and assessment of feature position errors have been investigated and a method using a 3-D least squares assessment has been found to be satisfactory. A graphical representation of the product model and errors has been developed using a 3-D solid modelling CAD system. The work has used golf balls and tooling as the product example

Greater Space Means More Service: Leveraging the innovative power of architecture and design

Organizational structures certainly are of great importance in order to determine employees’ behaviour and performance. On the other hand, physical structures also significantly influence the way staff and customers view any company and interact with it. In service based activity, such as in retailing, banking, hospitality, and so, firms and institutions are competing thanks to innovations in products/services, delivery processes, and management styles. Innovative approaches may also materialize into the design of facilities. Service providers are in a position to significantly improve convenience, productivity, and attractiveness by designing space and defining appropriate layout carefully. This pattern also has to include identification of the meanings, characterization of size and qualification of the process by which any service facility delivers messages. In the last session of the paper, we address a particular type of service facilities, namely the buildings of institutions for higher education in management. The objective is then to analyze how facilities have evolved in order to cope with the change affecting business education.Service; innovation; architecture; working place; corporate symbols

Two-Photon AMPK and ATP Imaging Reveals Metabolic Recovery in Mouse Rod Photoreceptor Cells

The title of publisher's version: Two-photon AMPK and ATP imaging reveals the bias between rods and cones in glycolysis utility.In vertebrates, retinal rod and cone photoreceptor cells rely significantly on glycolysis. Lactate released from photoreceptor cells fuels neighboring retinal pigment epithelium cells and Müller glial cells through oxidative phosphorylation. To understand this highly heterogeneous metabolic environment around photoreceptor cells, single-cell analysis is needed. Here, we visualized cellular AMP-activated protein kinase (AMPK) activity and ATP levels in the retina by two-photon microscopy. Transgenic mice expressing a hyBRET-AMPK biosensor were used for measuring the AMPK activity. GO-ATeam2 transgenic mice were used for measuring the ATP level. Temporal metabolic responses were successfully detected in the live retinal explants upon drug perfusion. A glycolysis inhibitor, 2-deoxy-d-glucose (2-DG), activated AMPK and reduced ATP. These effects were clearly stronger in rods than in cones. Notably, rod AMPK and ATP started to recover at 30 min from the onset of 2-DG perfusion. Consistent with these findings, ex vivo electroretinogram recordings showed a transient slowdown in rod dim flash responses during a 60-min 2-DG perfusion, whereas cone responses were not affected. Based on these results, we propose that cones surrounded by highly glycolytic rods become less dependent on glycolysis, and rods also become less dependent on glycolysis within 60 min upon the glycolysis inhibition

The specification of a consumer design toolkit to support personalised production via additive manufacturing

This thesis stems from the future scenario that as additive manufacturing (AM) technologies become cheaper and more readily available, consumers without formal design training will begin to customise, design and manufacture their own products. Much of this activity is likely to infringe on brands' intellectual property. The research explores the feasibility of a situation in which, rather than attempting to prohibit such activity, manufacturers engage with consumers to facilitate it, thus retaining control (albeit reduced) over their brand's image and the quality of products offered. The research begins with a literature review encompassing AM technologies and their adoption by consumers; mass customisation (MC) and the management of variation in product offering; and traditional models of industrial design (ID), including user-centred design and co-design. It finds that conventional definitions of MC and ID are unable to provide for the possibility of consumer intervention in the shape and non-modular configuration of products. Further research was then conducted in the areas of Open Design (including crowdsourcing, open sourcing and 'hardware hacking') as well as bespoke customisation, which were found to be much more accommodating of the scenario proposed. A new term, 'consumer design', is introduced and defined, together with the hypothesis that in future, the role of the industrial designer may be to design 'unfinished' products. An original classification of consumer involvement in ID is presented. Empirical research, undertaken with consumers using an iterative design software package (Genoform), demonstrated a preference for designing within pre-determined boundaries. Action research was conducted to assess consumer-oriented 3D CAD software, and compare its capabilities with that of MC toolkits. A survey of senior designers and brand managers revealed strategies for implementing and managing a brand's product design language, and a guide was created to show the relative importance of designed features. Using these findings, a prototype toolkit was created to demonstrate how a brand might facilitate consumer interaction with the shape design of a complex consumer electronics product (in this case a mobile phone). The toolkit was tested with both consumers and experienced designers to assess its viability. The research finds that it is possible to create a consumer-design toolkit which enables untrained users to change the form of a product, whilst maintaining brand equity and ensuring the product's functionality and manufacturability

3D numerical modelling and manipulation of a shoe last.

As global competition continues to increase causing market windows to shrink and product life cycles shorten, manufacturers today can no longer function without advanced design tools. These market pressures dictate that designers must embrace new, faster and better design technologies than ever before if they are to remain competitive. This is especially true in the shoe industry with the employment of up-to-date methods of design and manufacture. The development of modem CAD/CAM systems, the availability of powerful hardware at reasonable cost and vast improvements in colour graphics capabilities have made the automation of the footwear design process feasible at low cost. All of this economically justifies the creation of a system for direct shoe last design without a prototype model last. A specific onscreen methodology of a shoe last design directly from individual anthropometric data has been proposed and evaluated. A numerical methodology for onscreen visualisation with application of a new scheme of segmentation of the last surface and further manipulation of the last elements in order to create new last styles have been developed. In order to achieve this, the principles of shaping the last, the laws governing its deformation when changing the heel height and the list of possible modifications to its shape have been defined. Five global manipulation procedures have been implemented, in particular those that relate to changing the heel height. Special software has been written to visualise the results. Experimentation has proved the validity of the approach. Lasts of similar style but with different heel heights were measured and numerically modelled to compare with computer generated and modified last models. The accuracy proved to be within the limits of practical and traditional constraints