1,159 research outputs found

    Undergraduate Catalog of Studies, 2023-2024

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    Computational techniques to interpret the neural code underlying complex cognitive processes

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    Advances in large-scale neural recording technology have significantly improved the capacity to further elucidate the neural code underlying complex cognitive processes. This thesis aimed to investigate two research questions in rodent models. First, what is the role of the hippocampus in memory and specifically what is the underlying neural code that contributes to spatial memory and navigational decision-making. Second, how is social cognition represented in the medial prefrontal cortex at the level of individual neurons. To start, the thesis begins by investigating memory and social cognition in the context of healthy and diseased states that use non-invasive methods (i.e. fMRI and animal behavioural studies). The main body of the thesis then shifts to developing our fundamental understanding of the neural mechanisms underpinning these cognitive processes by applying computational techniques to ana lyse stable large-scale neural recordings. To achieve this, tailored calcium imaging and behaviour preprocessing computational pipelines were developed and optimised for use in social interaction and spatial navigation experimental analysis. In parallel, a review was conducted on methods for multivariate/neural population analysis. A comparison of multiple neural manifold learning (NML) algorithms identified that non linear algorithms such as UMAP are more adaptable across datasets of varying noise and behavioural complexity. Furthermore, the review visualises how NML can be applied to disease states in the brain and introduces the secondary analyses that can be used to enhance or characterise a neural manifold. Lastly, the preprocessing and analytical pipelines were combined to investigate the neural mechanisms in volved in social cognition and spatial memory. The social cognition study explored how neural firing in the medial Prefrontal cortex changed as a function of the social dominance paradigm, the "Tube Test". The univariate analysis identified an ensemble of behavioural-tuned neurons that fire preferentially during specific behaviours such as "pushing" or "retreating" for the animal’s own behaviour and/or the competitor’s behaviour. Furthermore, in dominant animals, the neural population exhibited greater average firing than that of subordinate animals. Next, to investigate spatial memory, a spatial recency task was used, where rats learnt to navigate towards one of three reward locations and then recall the rewarded location of the session. During the task, over 1000 neurons were recorded from the hippocampal CA1 region for five rats over multiple sessions. Multivariate analysis revealed that the sequence of neurons encoding an animal’s spatial position leading up to a rewarded location was also active in the decision period before the animal navigates to the rewarded location. The result posits that prospective replay of neural sequences in the hippocampal CA1 region could provide a mechanism by which decision-making is supported

    Graduate Catalog of Studies, 2023-2024

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    Undergraduate Catalog of Studies, 2023-2024

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    UMSL Bulletin 2023-2024

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    The 2023-2024 Bulletin and Course Catalog for the University of Missouri St. Louis.https://irl.umsl.edu/bulletin/1088/thumbnail.jp

    Graduate Catalog of Studies, 2023-2024

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    UMSL Bulletin 2022-2023

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    The 2022-2023 Bulletin and Course Catalog for the University of Missouri St. Louis.https://irl.umsl.edu/bulletin/1087/thumbnail.jp

    2023-2024 Catalog

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    The 2023-2024 Governors State University Undergraduate and Graduate Catalog is a comprehensive listing of current information regarding:Degree RequirementsCourse OfferingsUndergraduate and Graduate Rules and Regulation

    Video Summarization Using Unsupervised Deep Learning

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    In this thesis, we address the task of video summarization using unsupervised deep-learning architectures. Video summarization aims to generate a short summary by selecting the most informative and important frames (key-frames) or fragments (key-fragments) of the full-length video, and presenting them in temporally-ordered fashion. Our objective is to overcome observed weaknesses of existing video summarization approaches that utilize RNNs for modeling the temporal dependence of frames, related to: i) the small influence of the estimated frame-level importance scores in the created video summary, ii) the insufficiency of RNNs to model long-range frames' dependence, and iii) the small amount of parallelizable operations during the training of RNNs. To address the first weakness, we propose a new unsupervised network architecture, called AC-SUM-GAN, which formulates the selection of important video fragments as a sequence generation task and learns this task by embedding an Actor-Critic model in a Generative Adversarial Network. The feedback of a trainable Discriminator is used as a reward by the Actor-Critic model in order to explore a space of actions and learn a value function (Critic) and a policy (Actor) for video fragment selection. To tackle the remaining weaknesses, we investigate the use of attention mechanisms for video summarization and propose a new supervised network architecture, called PGL-SUM, that combines global and local multi-head attention mechanisms which take into account the temporal position of the video frames, in order to discover different modelings of the frames' dependencies at different levels of granularity. Based on the acquired experience, we then propose a new unsupervised network architecture, called CA-SUM, which estimates the frames' importance using a novel concentrated attention mechanism that focuses on non-overlapping blocks in the main diagonal of the attention matrix and takes into account the attentive uniqueness and diversity of the associated frames of the video. All the proposed architectures have been extensively evaluated on the most commonly-used benchmark datasets, demonstrating their competitiveness against other approaches and documenting the contribution of our proposals on advancing the current state-of-the-art on video summarization. Finally, we make a first attempt on producing explanations for the video summarization results. Inspired by relevant works in the Natural Language Processing domain, we propose an attention-based method for explainable video summarization and we evaluate the performance of various explanation signals using our CA-SUM architecture and two benchmark datasets for video summarization. The experimental results indicate the advanced performance of explanation signals formed using the inherent attention weights, and demonstrate the ability of the proposed method to explain the video summarization results using clues about the focus of the attention mechanism

    Undergraduate Catalog of Studies, 2022-2023

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