Mean-Field-Type Games in Engineering

A mean-field-type game is a game in which the instantaneous payoffs and/or the state dynamics functions involve not only the state and the action profile but also the joint distributions of state-action pairs. This article presents some engineering applications of mean-field-type games including road traffic networks, multi-level building evacuation, millimeter wave wireless communications, distributed power networks, virus spread over networks, virtual machine resource management in cloud networks, synchronization of oscillators, energy-efficient buildings, online meeting and mobile crowdsensing.Comment: 84 pages, 24 figures, 183 references. to appear in AIMS 201

Decentralized Massive MIMO Processing Exploring Daisy-chain Architecture and Recursive Algorithms

Algorithms for Massive MIMO uplink detection and downlink precoding typically rely on a centralized approach, by which baseband data from all antenna modules are routed to a central node in order to be processed. In the case of Massive MIMO, where hundreds or thousands of antennas are expected in the base-station, said routing becomes a bottleneck since interconnection throughput is limited. This paper presents a fully decentralized architecture and an algorithm for Massive MIMO uplink detection and downlink precoding based on the Stochastic Gradient Descent (SGD) method, which does not require a central node for these tasks. Through a recursive approach and very low complexity operations, the proposed algorithm provides a good trade-off between performance, interconnection throughput and latency. Further, our proposed solution achieves significantly lower interconnection data-rate than other architectures, enabling future scalability.Comment: Manuscript accepted for publication in IEEE Transactions on Signal Processin

Computational structure‐based drug design: Predicting target flexibility

The role of molecular modeling in drug design has experienced a significant revamp in the last decade. The increase in computational resources and molecular models, along with software developments, is finally introducing a competitive advantage in early phases of drug discovery. Medium and small companies with strong focus on computational chemistry are being created, some of them having introduced important leads in drug design pipelines. An important source for this success is the extraordinary development of faster and more efficient techniques for describing flexibility in three‐dimensional structural molecular modeling. At different levels, from docking techniques to atomistic molecular dynamics, conformational sampling between receptor and drug results in improved predictions, such as screening enrichment, discovery of transient cavities, etc. In this review article we perform an extensive analysis of these modeling techniques, dividing them into high and low throughput, and emphasizing in their application to drug design studies. We finalize the review with a section describing our Monte Carlo method, PELE, recently highlighted as an outstanding advance in an international blind competition and industrial benchmarks.We acknowledge the BSC-CRG-IRB Joint Research Program in Computational Biology. This work was supported by a grant from the Spanish Government CTQ2016-79138-R.J.I. acknowledges support from SVP-2014-068797, awarded by the Spanish Government.Peer ReviewedPostprint (author's final draft

Massive MIMO for Next Generation Wireless Systems

Multi-user Multiple-Input Multiple-Output (MIMO) offers big advantages over conventional point-to-point MIMO: it works with cheap single-antenna terminals, a rich scattering environment is not required, and resource allocation is simplified because every active terminal utilizes all of the time-frequency bins. However, multi-user MIMO, as originally envisioned with roughly equal numbers of service-antennas and terminals and frequency division duplex operation, is not a scalable technology. Massive MIMO (also known as "Large-Scale Antenna Systems", "Very Large MIMO", "Hyper MIMO", "Full-Dimension MIMO" & "ARGOS") makes a clean break with current practice through the use of a large excess of service-antennas over active terminals and time division duplex operation. Extra antennas help by focusing energy into ever-smaller regions of space to bring huge improvements in throughput and radiated energy efficiency. Other benefits of massive MIMO include the extensive use of inexpensive low-power components, reduced latency, simplification of the media access control (MAC) layer, and robustness to intentional jamming. The anticipated throughput depend on the propagation environment providing asymptotically orthogonal channels to the terminals, but so far experiments have not disclosed any limitations in this regard. While massive MIMO renders many traditional research problems irrelevant, it uncovers entirely new problems that urgently need attention: the challenge of making many low-cost low-precision components that work effectively together, acquisition and synchronization for newly-joined terminals, the exploitation of extra degrees of freedom provided by the excess of service-antennas, reducing internal power consumption to achieve total energy efficiency reductions, and finding new deployment scenarios. This paper presents an overview of the massive MIMO concept and contemporary research.Comment: Final manuscript, to appear in IEEE Communications Magazin