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Rapid (<5 min) identification of pathogen in human blood by electrokinetic concentration and surface-enhanced Raman spectroscopy.
This study reports a novel microfluidic platform for rapid and long-ranged concentration of rare-pathogen from human blood for subsequent on-chip surface-enhanced Raman spectroscopy (SERS) identification/discrimination of bacteria based on their detected fingerprints. Using a hybrid electrokinetic mechanism, bacteria can be concentrated at the stagnation area on the SERS-active roughened electrode, while blood cells were excluded away from this region at the center of concentric circular electrodes. This electrokinetic approach performs isolation and concentration of bacteria in about three minutes; the density factor is increased approximately a thousand fold in a local area of ~5000 Ī¼m(2) from a low bacteria concentration of 5 Ć 10(3)ā
CFU/ml. Besides, three genera of bacteria, S. aureus, E. coli, and P. aeruginosa that are found in most of the isolated infections in bacteremia were successfully identified in less than one minute on-chip without the use of any antibody/chemical immobilization and reaction processes
Spontaneous rotating vortex rings in a parametrically driven polariton fluid
We present the theoretical prediction of spontaneous rotating vortex rings in
a parametrically driven quantum fluid of polaritons -- coherent superpositions
of coupled quantum well excitons and microcavity photons. These rings arise not
only in the absence of any rotating drive, but also in the absence of a
trapping potential, in a model known to map quantitatively to experiments. We
begin by proposing a novel parametric pumping scheme for polaritons, with
circular symmetry and radial currents, and characterize the resulting
nonequilibrium condensate. We show that the system is unstable to spontaneous
breaking of circular symmetry via a modulational instability, following which a
vortex ring with large net angular momentum emerges, rotating in one of two
topologically distinct states. Such rings are robust and carry distinctive
experimental signatures, and so they could find applications in the new
generation of polaritonic devices.Comment: 6 pages, 4 figure
Pick matrix conditions for sign-definite solutions of the algebraic Riccati equation
We study the existence of positive and negative semidefinite solutions of algebraic Riccati equations (ARE) corresponding to linear quadratic problems with an indefinite cost functional. The problem to formulate reasonable necessary and sufficient conditions for the existence of such solutions is a long-standing open problem. A central role is played by certain two-variable polynomial matrices associated with the ARE. Our main result characterizes all unmixed solutions of the ARE in terms of the Pick matrices associated with these two-variable polynomial matrices. As a corollary of this result we obtain that the signatures of the extremal solutions of the ARE are determined by the signatures of particular Pick matrices
Spin interference effects in ring conductors subject to Rashba coupling
Quantum interference effects in rings provide suitable means for controlling
spin at mesoscopic scales. Here we apply such control mechanisms to coherent
spin-dependent transport in one- and two-dimensional rings subject to Rashba
spin-orbit coupling. We first study the spin-induced modulation of unpolarized
currents as a function of the Rashba coupling strength. The results suggest the
possibility of all-electrical spintronic devices. Moreover, we find signatures
of Berry phases in the conductance previously unnoticed. Second, we show that
the polarization direction of initially polarized, transmitted spins can be
tuned via an additional small magnetic control flux. In particular, this
enables to precisely reverse the polarization direction at half a flux quantum.
We present full numerical calculations for realistic two-dimensional ballistic
microstructures and explain our findings in a simple analytical model for
one-dimensional rings.Comment: 8 pages, 5 figures. Submitted to Phys. Rev. B, final versio
Neutrino Physics at a Muon Collider
An overview is given of the neutrino physics potential of future muon storage
rings that use muon collider technology to produce, accelerate and store large
currents of muons.Comment: 15 pages. 1 figur
Quantum Transport in Nonuniform Magnetic Fields: Aharonov-Bohm Ring as a Spin Switch
We study the spin-dependent magneto conductance in mesoscopic rings subject
to an inhomogeneous in-plane magnetic field. We show that the polarization
direction of transmitted spin-polarized electrons can be controlled via an
additional magnetic flux such that spin flips are induced at half a flux
quantum. This quantum interference effect is independent of the strength of the
nonuniform field applied. We give an analytical explanation for one-dimensional
rings and numerical results for corresponding ballistic microstructures.Comment: 5 pages, 3 figures. To be published in Physical Review Letter
Non-stationary coherent quantum many-body dynamics through dissipation
The assumption that quantum systems relax to a stationary state in the
long-time limit underpins statistical physics and much of our intuitive
understanding of scientific phenomena. For isolated systems this follows from
the eigenstate thermalization hypothesis. When an environment is present the
expectation is that all of phase space is explored, eventually leading to
stationarity. Notable exceptions are decoherence-free subspaces that have
important implications for quantum technologies and have so far only been
studied for systems with a few degrees of freedom. Here we identify simple and
generic conditions for dissipation to prevent a quantum many-body system from
ever reaching a stationary state. We go beyond dissipative quantum state
engineering approaches towards controllable long-time non-stationarity
typically associated with macroscopic complex systems. This coherent and
oscillatory evolution constitutes a dissipative version of a quantum
time-crystal. We discuss the possibility of engineering such complex dynamics
with fermionic ultracold atoms in optical lattices.Comment: Main text in MS Word (10 pages, 4 figures) and Supplementary material
in TeX (10 pages, 2 figures). Main text PDF embedded in TeX. Version as
accepted by Nature Communication
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