15,219 research outputs found
Globally Optimal Cell Tracking using Integer Programming
We propose a novel approach to automatically tracking cell populations in
time-lapse images. To account for cell occlusions and overlaps, we introduce a
robust method that generates an over-complete set of competing detection
hypotheses. We then perform detection and tracking simultaneously on these
hypotheses by solving to optimality an integer program with only one type of
flow variables. This eliminates the need for heuristics to handle missed
detections due to occlusions and complex morphology. We demonstrate the
effectiveness of our approach on a range of challenging sequences consisting of
clumped cells and show that it outperforms state-of-the-art techniques.Comment: Engin T\"uretken and Xinchao Wang contributed equally to this wor
An Automatic Level Set Based Liver Segmentation from MRI Data Sets
A fast and accurate liver segmentation method is a challenging work in medical image analysis area. Liver segmentation is an important process for computer-assisted diagnosis, pre-evaluation of liver transplantation and therapy planning of liver tumors. There are several advantages of magnetic resonance imaging such as free form ionizing radiation and good contrast visualization of soft tissue. Also, innovations in recent technology and image acquisition techniques have made magnetic resonance imaging a major tool in modern medicine. However, the use of magnetic resonance images for liver segmentation has been slow when we compare applications with the central nervous systems and musculoskeletal. The reasons are irregular shape, size and position of the liver, contrast agent effects and similarities of the gray values of neighbor organs. Therefore, in this study, we present a fully automatic liver segmentation method by using an approximation of the level set based contour evolution from T2 weighted magnetic resonance data sets. The method avoids solving partial differential equations and applies only integer operations with a two-cycle segmentation algorithm. The efficiency of the proposed approach is achieved by applying the algorithm to all slices with a constant number of iteration and performing the contour evolution without any user defined initial contour. The obtained results are evaluated with four different similarity measures and they show that the automatic segmentation approach gives successful results
Visual Quality Enhancement in Optoacoustic Tomography using Active Contour Segmentation Priors
Segmentation of biomedical images is essential for studying and
characterizing anatomical structures, detection and evaluation of pathological
tissues. Segmentation has been further shown to enhance the reconstruction
performance in many tomographic imaging modalities by accounting for
heterogeneities of the excitation field and tissue properties in the imaged
region. This is particularly relevant in optoacoustic tomography, where
discontinuities in the optical and acoustic tissue properties, if not properly
accounted for, may result in deterioration of the imaging performance.
Efficient segmentation of optoacoustic images is often hampered by the
relatively low intrinsic contrast of large anatomical structures, which is
further impaired by the limited angular coverage of some commonly employed
tomographic imaging configurations. Herein, we analyze the performance of
active contour models for boundary segmentation in cross-sectional optoacoustic
tomography. The segmented mask is employed to construct a two compartment model
for the acoustic and optical parameters of the imaged tissues, which is
subsequently used to improve accuracy of the image reconstruction routines. The
performance of the suggested segmentation and modeling approach are showcased
in tissue-mimicking phantoms and small animal imaging experiments.Comment: Accepted for publication in IEEE Transactions on Medical Imagin
Hierarchical Object Parsing from Structured Noisy Point Clouds
Object parsing and segmentation from point clouds are challenging tasks
because the relevant data is available only as thin structures along object
boundaries or other features, and is corrupted by large amounts of noise. To
handle this kind of data, flexible shape models are desired that can accurately
follow the object boundaries. Popular models such as Active Shape and Active
Appearance models lack the necessary flexibility for this task, while recent
approaches such as the Recursive Compositional Models make model
simplifications in order to obtain computational guarantees. This paper
investigates a hierarchical Bayesian model of shape and appearance in a
generative setting. The input data is explained by an object parsing layer,
which is a deformation of a hidden PCA shape model with Gaussian prior. The
paper also introduces a novel efficient inference algorithm that uses informed
data-driven proposals to initialize local searches for the hidden variables.
Applied to the problem of object parsing from structured point clouds such as
edge detection images, the proposed approach obtains state of the art parsing
errors on two standard datasets without using any intensity information.Comment: 13 pages, 16 figure
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