Retinal vessel segmentation using textons

Segmenting vessels from retinal images, like segmentation in many other medical image domains, is a challenging task, as there is no unified way that can be adopted to extract the vessels accurately. However, it is the most critical stage in automatic assessment of various forms of diseases (e.g. Glaucoma, Age-related macular degeneration, diabetic retinopathy and cardiovascular diseases etc.). Our research aims to investigate retinal image segmentation approaches based on textons as they provide a compact description of texture that can be learnt from a training set. This thesis presents a brief review of those diseases and also includes their current situations, future trends and techniques used for their automatic diagnosis in routine clinical applications. The importance of retinal vessel segmentation is particularly emphasized in such applications. An extensive review of previous work on retinal vessel segmentation and salient texture analysis methods is presented. Five automatic retinal vessel segmentation methods are proposed in this thesis. The first method focuses on addressing the problem of removing pathological anomalies (Drusen, exudates) for retinal vessel segmentation, which have been identified by other researchers as a problem and a common source of error. The results show that the modified method shows some improvement compared to a previously published method. The second novel supervised segmentation method employs textons. We propose a new filter bank (MR11) that includes bar detectors for vascular feature extraction and other kernels to detect edges and photometric variations in the image. The k-means clustering algorithm is adopted for texton generation based on the vessel and non-vessel elements which are identified by ground truth. The third improved supervised method is developed based on the second one, in which textons are generated by k-means clustering and texton maps representing vessels are derived by back projecting pixel clusters onto hand labelled ground truth. A further step is implemented to ensure that the best combinations of textons are represented in the map and subsequently used to identify vessels in the test set. The experimental results on two benchmark datasets show that our proposed method performs well compared to other published work and the results of human experts. A further test of our system on an independent set of optical fundus images verified its consistent performance. The statistical analysis on experimental results also reveals that it is possible to train unified textons for retinal vessel segmentation. In the fourth method a novel scheme using Gabor filter bank for vessel feature extraction is proposed. The ii method is inspired by the human visual system. Machine learning is used to optimize the Gabor filter parameters. The experimental results demonstrate that our method significantly enhances the true positive rate while maintaining a level of specificity that is comparable with other approaches. Finally, we proposed a new unsupervised texton based retinal vessel segmentation method using derivative of SIFT and multi-scale Gabor filers. The lack of sufficient quantities of hand labelled ground truth and the high level of variability in ground truth labels amongst experts provides the motivation for this approach. The evaluation results reveal that our unsupervised segmentation method is comparable with the best other supervised methods and other best state of the art methods

Local and deep texture features for classification of natural and biomedical images

Developing efficient feature descriptors is very important in many computer vision applications including biomedical image analysis. In the past two decades and before the popularity of deep learning approaches in image classification, texture features proved to be very effective to capture the gradient variation in the image. Following the success of the Local Binary Pattern (LBP) descriptor, many variations of this descriptor were introduced to further improve the ability of obtaining good classification results. However, the problem of image classification gets more complicated when the number of images increases as well as the number of classes. In this case, more robust approaches must be used to address this problem. In this thesis, we address the problem of analyzing biomedical images by using a combination of local and deep features. First, we propose a novel descriptor that is based on the motif Peano scan concept called Joint Motif Labels (JML). After that, we combine the features extracted from the JML descriptor with two other descriptors called Rotation Invariant Co-occurrence among Local Binary Patterns (RIC-LBP) and Joint Adaptive Medina Binary Patterns (JAMBP). In addition, we construct another descriptor called Motif Patterns encoded by RIC-LBP and use it in our classification framework. We enrich the performance of our framework by combining these local descriptors with features extracted from a pre-trained deep network called VGG-19. Hence, the 4096 features of the Fully Connected 'fc7' layer are extracted and combined with the proposed local descriptors. Finally, we show that Random Forests (RF) classifier can be used to obtain superior performance in the field of biomedical image analysis. Testing was performed on two standard biomedical datasets and another three standard texture datasets. Results show that our framework can beat state-of-the-art accuracy on the biomedical image analysis and the combination of local features produce promising results on the standard texture datasets.Includes bibliographical reference

Contour and texture for visual recognition of object categories

The recognition of categories of objects in images has become a central topic in computer vision. Automatic visual recognition systems are rapidly becoming central to applications such as image search, robotics, vehicle safety systems, and image editing. This work addresses three sub-problems of recognition: image classification, object detection, and semantic segmentation. The task of classification is to determine whether an object of a particular category is present or not. Object detection aims to localize any objects of the category. Semantic segmentation is a more complete image understanding, whereby an image is partitioned into coherent regions that are assigned meaningful class labels. This thesis proposes novel discriminative learning approaches to these problems. Our primary contributions are threefold. Firstly, we demonstrate that the contours (the outline and interior edges) of an object are, alone, sufficient for accurate visual recognition. Secondly, we propose two powerful new feature types: (i) a learned codebook of contour fragments matched with an improved oriented chamfer distance, and (ii) a set of texture-based features that simultaneously exploit local appearance, approximate shape, and appearance context. The efficacy of these new features types is evaluated on a wide variety of datasets. Thirdly, we show how, in combination, these two largely orthogonal feature types can substantially improve recognition performance above that achieved by either alone

Local Features and Kernels for Classification of Texture and Object Categories: An In-Depth Study

Recently, methods based on local image features have shown promise for texture and object recognition tasks. This paper presents a large-scale evaluation of an approach that represents images as distributions (signatures or histograms) of features extracted from a sparse set of keypoint locations and learns a Support Vector Machine classifier with kernels based on two effective measures for comparing distributions, the Earth Mover's Distance and the chi-square distance. We first evaluate the performance of our approach with different keypoint detectors and descriptors, as well as different kernels and classifiers. We then conduct a comparative evaluation with several state-of-the-art recognition methods on four texture and five object databases. On most of these databases, our implementation exceeds the best reported results and achieves comparable performance on the rest. Finally, we investigate the influence of background correlations on recognition performance via extensive tests on the PASCAL database, for which ground-truth object localization information is available. Our experiments demonstrate that image representations based on distributions of local features are surprisingly effective for classification of texture and object images under challenging real-world conditions, including significant intra-class variations and substantial background clutter.Les méthodes basées sur des descripteurs d'images locaux ont récemment donné de bons résultats en reconnaissance d'objets et de textures. Cet article évalue la pertinence d'une représentation d'image par une distribution (signature, histogramme) de descripteurs calculés en des points d'intérêt, et d'une classification par Machine à Vecteur Support dont les noyaux utilisent des mesures adaptées à la comparaison de distributions (Earth Mover Distance, chi-square). Dans un premier temps nous évaluons la performance de notre approche avec différentes combinaisons de détecteurs de points d'intérêt, de descripteurs, de noyaux et de classifieurs. Puis nous comparons nos résultats avec des méthodes de l'état de l'art sur quatre bases de textures et cinq bases d'objets. Sur la plupart de ces bases, nos performances sont meilleures que celles de l'état de l'art et comparables pour le reste. Enfin, nous mesurons l'influence de la corrélation des fonds sur les performances de reconnaissance sur la base PASCAL, pour laquelle on dispose de la localisation exacte des objets. Nos expérimentations démontrent que la représentation d'images à base de distribution de descripteurs locaux est très efficace pour la classification d'objets et de textures, dans des conditions réelles telles que de fortes variations intra-classes et un fond complexe