670 research outputs found

    Wearable Sensors Applied in Movement Analysis

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    Recent advances in electronics have led to sensors whose sizes and weights are such that they can be placed on living systems without impairing their natural motion and habits. They may be worn on the body as accessories or as part of the clothing and enable personalized mobile information processing. Wearable sensors open the way for a nonintrusive and continuous monitoring of body orientation, movements, and various physiological parameters during motor activities in real-life settings. Thus, they may become crucial tools not only for researchers, but also for clinicians, as they have the potential to improve diagnosis, better monitor disease development and thereby individualize treatment. Wearable sensors should obviously go unnoticed for the people wearing them and be intuitive in their installation. They should come with wireless connectivity and low-power consumption. Moreover, the electronics system should be self-calibrating and deliver correct information that is easy to interpret. Cross-platform interfaces that provide secure data storage and easy data analysis and visualization are needed.This book contains a selection of research papers presenting new results addressing the above challenges

    Machine Learning and Similarity Network Approaches to Support Automatic Classification of Parkinson’s Diseases Using Accelerometer-based Gait Analysis

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    Parkinson’s Disease is a worldwide health problem, causing movement disorder and gait deficiencies. Automatic noninvasive techniques for Parkinson\u27s disease diagnosis is appreciated by patients, clinicians and neuroscientists. Gait offers many advantages compared to other biometrics specifically when data is collected using wearable devices; data collection can be performed through inexpensive technologies, remotely, and continuously. In this study, a new set of gait features associated with Parkinson’s Disease are introduced and extracted from accelerometer data. Then, we used a feature selection technique called maximum information gain minimum correlation (MIGMC). Using MIGMC, features are first reduced based on Information Gain method and then through Pearson correlation analysis and Tukey post-hoc multiple comparison test. The ability of several machine learning methods, including Support Vector Machine, Random Forest, AdaBoost, Bagging, and Naïve Bayes are investigated across different feature sets. Similarity Network analysis is also performed to validate our optimal feature set obtained using MIGMC technique. The effect of feature standardization is also investigated. Results indicates that standardization could improve all classifiers’ performance. In addition, the feature set obtained using MIGMC provided the highest classification performance. It is shown that our results from Similarity Network analysis are consistent with our results from the classification task, emphasizing on the importance of choosing an optimal set of gait features to help objective assessment and automatic diagnosis of Parkinson’s disease. Results illustrate that ensemble methods and specifically boosting classifiers had better performances than other classifiers. In summary, our preliminary results support the potential benefit of accelerometers as an objective tool for diagnostic purposes in PD

    High-Resolution Motor State Detection in Parkinson's Disease Using Convolutional Neural Networks

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    Patients with advanced Parkinson's disease regularly experience unstable motor states. Objective and reliable monitoring of these fluctuations is an unmet need. We used deep learning to classify motion data from a single wrist-worn IMU sensor recording in unscripted environments. For validation purposes, patients were accompanied by a movement disorder expert, and their motor state was passively evaluated every minute. We acquired a dataset of 8,661 minutes of IMU data from 30 patients, with annotations about the motor state (OFF,ON, DYSKINETIC) based on MDS-UPDRS global bradykinesia item and the AIMS upper limb dyskinesia item. Using a 1-minute window size as an input for a convolutional neural network trained on data from a subset of patients, we achieved a three-class balanced accuracy of 0.654 on data from previously unseen subjects. This corresponds to detecting the OFF, ON, or DYSKINETIC motor state at a sensitivity/specificity of 0.64/0.89, 0.67/0.67 and 0.64/0.89, respectively. On average, the model outputs were highly correlated with the annotation on a per subject scale (r = 0.83/0.84;p < 0.0001), and sustained so for the highly resolved time windows of 1 minute (r = 0.64/0.70;p < 0.0001). Thus, we demonstrate the feasibility of long-term motor-state detection in a free-living setting with deep learning using motion data from a single IMU

    Prediction of Fall Risk Among Community-Dwelling Older Adults Using a Wearable System

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    Falls are among the most common cause of decreased mobility and independence in older adults and rank as one of the most severe public health problems with frequent fatal consequences. In the present study, gait characteristics from 171 community-dwelling older adults were evaluated to determine their predictive ability for future falls using a wearable system. Participants wore a wearable sensor (inertial measurement unit, IMU) affixed to the sternum and performed a 10-m walking test. Measures of gait variability, complexity, and smoothness were extracted from each participant, and prospective fall incidence was evaluated over the following 6-months. Gait parameters were refined to better represent features for a random forest classifier for the fall-risk classification utilizing three experiments. The results show that the best-trained model for faller classification used both linear and nonlinear gait parameters and achieved an overall 81.6 ± 0.7% accuracy, 86.7 ± 0.5% sensitivity, 80.3 ± 0.2% specificity in the blind test. These findings augment the wearable sensor\u27s potential as an ambulatory fall risk identification tool in community-dwelling settings. Furthermore, they highlight the importance of gait features that rely less on event detection methods, and more on time series analysis techniques. Fall prevention is a critical component in older individuals’ healthcare, and simple models based on gait-related tasks and a wearable IMU sensor can determine the risk of future falls
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