Feasibility of automated 3-dimensional magnetic resonance imaging pancreas segmentation.

PurposeWith the advent of MR guided radiotherapy, internal organ motion can be imaged simultaneously during treatment. In this study, we evaluate the feasibility of pancreas MRI segmentation using state-of-the-art segmentation methods.Methods and materialT2 weighted HASTE and T1 weighted VIBE images were acquired on 3 patients and 2 healthy volunteers for a total of 12 imaging volumes. A novel dictionary learning (DL) method was used to segment the pancreas and compared to t mean-shift merging (MSM), distance regularized level set (DRLS), graph cuts (GC) and the segmentation results were compared to manual contours using Dice's index (DI), Hausdorff distance and shift of the-center-of-the-organ (SHIFT).ResultsAll VIBE images were successfully segmented by at least one of the auto-segmentation method with DI >0.83 and SHIFT ≤2 mm using the best automated segmentation method. The automated segmentation error of HASTE images was significantly greater. DL is statistically superior to the other methods in Dice's overlapping index. For the Hausdorff distance and SHIFT measurement, DRLS and DL performed slightly superior to the GC method, and substantially superior to MSM. DL required least human supervision and was faster to compute.ConclusionOur study demonstrated potential feasibility of automated segmentation of the pancreas on MRI images with minimal human supervision at the beginning of imaging acquisition. The achieved accuracy is promising for organ localization

Machine learning : techniques and foundations

The field of machine learning studies computational methods for acquiring new knowledge, new skills, and new ways to organize existing knowledge. In this paper we present some of the basic techniques and principles that underlie AI research on learning, including methods for learning from examples, learning in problem solving, learning by analogy, grammar acquisition, and machine discovery. In each case, we illustrate the techniques with paradigmatic examples

Minimally supervised induction of morphology through bitexts

textA knowledge of morphology can be useful for many natural language processing systems. Thus, much effort has been expended in developing accurate computational tools for morphology that lemmatize, segment and generate new forms. The most powerful and accurate of these have been manually encoded, such endeavors being without exception expensive and time-consuming. There have been consequently many attempts to reduce this cost in the development of morphological systems through the development of unsupervised or minimally supervised algorithms and learning methods for acquisition of morphology. These efforts have yet to produce a tool that approaches the performance of manually encoded systems. Here, I present a strategy for dealing with morphological clustering and segmentation in a minimally supervised manner but one that will be more linguistically informed than previous unsupervised approaches. That is, this study will attempt to induce clusters of words from an unannotated text that are inflectional variants of each other. Then a set of inflectional suffixes by part-of-speech will be induced from these clusters. This level of detail is made possible by a method known as alignment and transfer (AT), among other names, an approach that uses aligned bitexts to transfer linguistic resources developed for one language–the source language–to another language–the target. This approach has a further advantage in that it allows a reduction in the amount of training data without a significant degradation in performance making it useful in applications targeted at data collected from endangered languages. In the current study, however, I use English as the source and German as the target for ease of evaluation and for certain typlogical properties of German. The two main tasks, that of clustering and segmentation, are approached as sequential tasks with the clustering informing the segmentation to allow for greater accuracy in morphological analysis. While the performance of these methods does not exceed the current roster of unsupervised or minimally supervised approaches to morphology acquisition, it attempts to integrate more learning methods than previous studies. Furthermore, it attempts to learn inflectional morphology as opposed to derivational morphology, which is a crucial distinction in linguistics.Linguistic

Language acquisition and machine learning

In this paper, we review recent progress in the field of machine learning and examine its implications for computational models of language acquisition. As a framework for understanding this research, we propose four component tasks involved in learning from experience - aggregation, clustering, characterization, and storage. We then consider four common problems studied by machine learning researchers - learning from examples, heuristics learning, conceptual clustering, and learning macro-operators - describing each in terms of our framework. After this, we turn to the problem of grammar acquisition, relating this problem to other learning tasks and reviewing four AI systems that have addressed the problem. Finally, we note some limitations of the earlier work and propose an alternative approach to modeling the mechanisms underlying language acquisition

A foundation for machine learning in design

This paper presents a formalism for considering the issues of learning in design. A foundation for machine learning in design (MLinD) is defined so as to provide answers to basic questions on learning in design, such as, "What types of knowledge can be learnt?", "How does learning occur?", and "When does learning occur?". Five main elements of MLinD are presented as the input knowledge, knowledge transformers, output knowledge, goals/reasons for learning, and learning triggers. Using this foundation, published systems in MLinD were reviewed. The systematic review presents a basis for validating the presented foundation. The paper concludes that there is considerable work to be carried out in order to fully formalize the foundation of MLinD