75,548 research outputs found

    Degeneracy: a link between evolvability, robustness and complexity in biological systems

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    A full accounting of biological robustness remains elusive; both in terms of the mechanisms by which robustness is achieved and the forces that have caused robustness to grow over evolutionary time. Although its importance to topics such as ecosystem services and resilience is well recognized, the broader relationship between robustness and evolution is only starting to be fully appreciated. A renewed interest in this relationship has been prompted by evidence that mutational robustness can play a positive role in the discovery of adaptive innovations (evolvability) and evidence of an intimate relationship between robustness and complexity in biology. This paper offers a new perspective on the mechanics of evolution and the origins of complexity, robustness, and evolvability. Here we explore the hypothesis that degeneracy, a partial overlap in the functioning of multi-functional components, plays a central role in the evolution and robustness of complex forms. In support of this hypothesis, we present evidence that degeneracy is a fundamental source of robustness, it is intimately tied to multi-scaled complexity, and it establishes conditions that are necessary for system evolvability

    The Hollow Promise of an Accounting Standard Setter

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    Purpose – This paper applies a power framework to critically analyse the international accounting standard setting process for the extractive industries. Design/methodology/approach – Publicly available data, including comment letters, annual reports, company websites, and IASC/IASB pronouncements, is used to make connections between the key plays involved in the international accounting standard setting process for the extractive industries. Findings – Lukes’ (1974) conception of power is used to explain the community of interests that developed between the IASC/IASB and extractive industries constituents. This community of interests is shown to have enabled the extractive industries to mobilise its power to paralyse the standard setting body and secure favourable regulation. While the politicisation of accounting standard setting is widely acknowledged, the revelation that economically dominant groups can covertly wield such power is a sobering one in the light of the worldwide promotion and adoption of International Financial Reporting Standards. Originality/value – This paper contributes to understanding of the presence of power in the international accounting standard setting process and how it is mobilised by key constituents

    Magnetoencephalography in Stroke Recovery and Rehabilitation

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    Magnetoencephalography (MEG) is a non-invasive neurophysiological technique used to study the cerebral cortex. Currently, MEG is mainly used clinically to localize epileptic foci and eloquent brain areas in order to avoid damage during neurosurgery. MEG might, however, also be of help in monitoring stroke recovery and rehabilitation. This review focuses on experimental use of MEG in neurorehabilitation. MEG has been employed to detect early modifications in neuroplasticity and connectivity, but there is insufficient evidence as to whether these methods are sensitive enough to be used as a clinical diagnostic test. MEG has also been exploited to derive the relationship between brain activity and movement kinematics for a motor-based brain-computer interface. In the current body of experimental research, MEG appears to be a powerful tool in neurorehabilitation, but it is necessary to produce new data to confirm its clinical utility

    Depicting urban boundaries from a mobility network of spatial interactions: A case study of Great Britain with geo-located Twitter data

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    Existing urban boundaries are usually defined by government agencies for administrative, economic, and political purposes. Defining urban boundaries that consider socio-economic relationships and citizen commute patterns is important for many aspects of urban and regional planning. In this paper, we describe a method to delineate urban boundaries based upon human interactions with physical space inferred from social media. Specifically, we depicted the urban boundaries of Great Britain using a mobility network of Twitter user spatial interactions, which was inferred from over 69 million geo-located tweets. We define the non-administrative anthropographic boundaries in a hierarchical fashion based on different physical movement ranges of users derived from the collective mobility patterns of Twitter users in Great Britain. The results of strongly connected urban regions in the form of communities in the network space yield geographically cohesive, non-overlapping urban areas, which provide a clear delineation of the non-administrative anthropographic urban boundaries of Great Britain. The method was applied to both national (Great Britain) and municipal scales (the London metropolis). While our results corresponded well with the administrative boundaries, many unexpected and interesting boundaries were identified. Importantly, as the depicted urban boundaries exhibited a strong instance of spatial proximity, we employed a gravity model to understand the distance decay effects in shaping the delineated urban boundaries. The model explains how geographical distances found in the mobility patterns affect the interaction intensity among different non-administrative anthropographic urban areas, which provides new insights into human spatial interactions with urban space.Comment: 32 pages, 7 figures, International Journal of Geographic Information Scienc
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