30,736 research outputs found
An Adversarial Super-Resolution Remedy for Radar Design Trade-offs
Radar is of vital importance in many fields, such as autonomous driving,
safety and surveillance applications. However, it suffers from stringent
constraints on its design parametrization leading to multiple trade-offs. For
example, the bandwidth in FMCW radars is inversely proportional with both the
maximum unambiguous range and range resolution. In this work, we introduce a
new method for circumventing radar design trade-offs. We propose the use of
recent advances in computer vision, more specifically generative adversarial
networks (GANs), to enhance low-resolution radar acquisitions into higher
resolution counterparts while maintaining the advantages of the low-resolution
parametrization. The capability of the proposed method was evaluated on the
velocity resolution and range-azimuth trade-offs in micro-Doppler signatures
and FMCW uniform linear array (ULA) radars, respectively.Comment: Accepted in EUSIPCO 2019, 5 page
Collaborative sparse regression using spatially correlated supports - Application to hyperspectral unmixing
This paper presents a new Bayesian collaborative sparse regression method for
linear unmixing of hyperspectral images. Our contribution is twofold; first, we
propose a new Bayesian model for structured sparse regression in which the
supports of the sparse abundance vectors are a priori spatially correlated
across pixels (i.e., materials are spatially organised rather than randomly
distributed at a pixel level). This prior information is encoded in the model
through a truncated multivariate Ising Markov random field, which also takes
into consideration the facts that pixels cannot be empty (i.e, there is at
least one material present in each pixel), and that different materials may
exhibit different degrees of spatial regularity. Secondly, we propose an
advanced Markov chain Monte Carlo algorithm to estimate the posterior
probabilities that materials are present or absent in each pixel, and,
conditionally to the maximum marginal a posteriori configuration of the
support, compute the MMSE estimates of the abundance vectors. A remarkable
property of this algorithm is that it self-adjusts the values of the parameters
of the Markov random field, thus relieving practitioners from setting
regularisation parameters by cross-validation. The performance of the proposed
methodology is finally demonstrated through a series of experiments with
synthetic and real data and comparisons with other algorithms from the
literature
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The Landscape of Long Non-Coding RNA Dysregulation and Clinical Relevance in Muscle Invasive Bladder Urothelial Carcinoma.
Bladder cancer is one of the most common cancers in the United States, but few advancements in treatment options have occurred in the past few decades. This study aims to identify the most clinically relevant long non-coding RNAs (lncRNAs) to serve as potential biomarkers and treatment targets for muscle invasive bladder cancer (MIBC). Using RNA-sequencing data from 406 patients in The Cancer Genome Atlas (TCGA) database, we identified differentially expressed lncRNAs in MIBC vs. normal tissues. We then associated lncRNA expression with patient survival, clinical variables, oncogenic signatures, cancer- and immune-associated pathways, and genomic alterations. We identified a panel of 20 key lncRNAs that were most implicated in MIBC prognosis after differential expression analysis and prognostic correlations. Almost all lncRNAs we identified are correlated significantly with oncogenic processes. In conclusion, we discovered previously undescribed lncRNAs strongly implicated in the MIBC disease course that may be leveraged for diagnostic and treatment purposes in the future. Functional analysis of these lncRNAs may also reveal distinct mechanisms of bladder cancer carcinogenesis
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