320,141 research outputs found
Magnetoencephalography in Stroke Recovery and Rehabilitation
Magnetoencephalography (MEG) is a non-invasive neurophysiological technique used to study the cerebral cortex. Currently, MEG is mainly used clinically to localize epileptic foci and eloquent brain areas in order to avoid damage during neurosurgery. MEG might, however, also be of help in monitoring stroke recovery and rehabilitation. This review focuses on experimental use of MEG in neurorehabilitation. MEG has been employed to detect early modifications in neuroplasticity and connectivity, but there is insufficient evidence as to whether these methods are sensitive enough to be used as a clinical diagnostic test. MEG has also been exploited to derive the relationship between brain activity and movement kinematics for a motor-based brain-computer interface. In the current body of experimental research, MEG appears to be a powerful tool in neurorehabilitation, but it is necessary to produce new data to confirm its clinical utility
Route Planning in Transportation Networks
We survey recent advances in algorithms for route planning in transportation
networks. For road networks, we show that one can compute driving directions in
milliseconds or less even at continental scale. A variety of techniques provide
different trade-offs between preprocessing effort, space requirements, and
query time. Some algorithms can answer queries in a fraction of a microsecond,
while others can deal efficiently with real-time traffic. Journey planning on
public transportation systems, although conceptually similar, is a
significantly harder problem due to its inherent time-dependent and
multicriteria nature. Although exact algorithms are fast enough for interactive
queries on metropolitan transit systems, dealing with continent-sized instances
requires simplifications or heavy preprocessing. The multimodal route planning
problem, which seeks journeys combining schedule-based transportation (buses,
trains) with unrestricted modes (walking, driving), is even harder, relying on
approximate solutions even for metropolitan inputs.Comment: This is an updated version of the technical report MSR-TR-2014-4,
previously published by Microsoft Research. This work was mostly done while
the authors Daniel Delling, Andrew Goldberg, and Renato F. Werneck were at
Microsoft Research Silicon Valle
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