18,270 research outputs found

    Keywords given by authors of scientific articles in database descriptors

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    This paper analyses the keywords given by authors of scientific articles and the descriptors assigned to the articles in order to ascertain the presence of the keywords in the descriptors. 640 INSPEC, CAB abstracts, ISTA and LISA database records were consulted. After detailed comparisons it was found that keywords provided by authors have an important presence in the database descriptors studied, since nearly 25% of all the keywords appeared in exactly the same form as descriptors, with another 21% while normalized, are still detected in the descriptors. This means that almost 46% of keywords appear in the descriptors, either as such or after normalization. Elsewhere, three distinct indexing policies appear, one represented by INSPEC and LISA (indexers seem to have freedom to assign the descriptors they deem necessary); another is represented by CAB (no record has fewer than four descriptors and, in general, a large number of descriptors is employed; in contrast, in ISTA, a certain institutional code towards economy in indexing, since 84% of records contain only four descriptors

    Detection of Hard Exudates in Retinal Fundus Images using Deep Learning

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    Diabetic Retinopathy (DR) is a retinal disorder that affects the people having diabetes mellitus for a long time (20 years). DR is one of the main reasons for the preventable blindness all over the world. If not detected early the patient may progress to severe stages of irreversible blindness. Lack of Ophthalmologists poses a serious problem for the growing diabetes patients. It is advised to develop an automated DR screening system to assist the Ophthalmologist in decision making. Hard exudates develop when DR is present. It is important to detect hard exudates in order to detect DR in an early stage. Research has been done to detect hard exudates using regular image processing techniques and Machine Learning techniques. Here, a deep learning algorithm has been presented in this paper that detects hard exudates in fundus images of the retina.Comment: 5 Pages, 3 figures, 2 tables, International Conference on Systems, Computation, Automation and Networking http://icscan.in

    Structural identifiability analyses of candidate models for in vitro Pitavastatin hepatic uptake

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    In this paper a review of the application of four different techniques (a version of the similarity transformation approach for autonomous uncontrolled systems, a non-differential input/output observable normal form approach, the characteristic set differential algebra and a recent algebraic input/output relationship approach) to determine the structural identifiability of certain in vitro nonlinear pharmacokinetic models is provided. The Organic Anion Transporting Polypeptide (OATP) substrate, Pitavastatin, is used as a probe on freshly isolated animal and human hepatocytes. Candidate pharmacokinetic non-linear compartmental models have been derived to characterise the uptake process of Pitavastatin. As a prerequisite to parameter estimation, structural identifiability analyses are performed to establish that all unknown parameters can be identified from the experimental observations available

    A Study of Speed of the Boundary Element Method as applied to the Realtime Computational Simulation of Biological Organs

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    In this work, possibility of simulating biological organs in realtime using the Boundary Element Method (BEM) is investigated. Biological organs are assumed to follow linear elastostatic material behavior, and constant boundary element is the element type used. First, a Graphics Processing Unit (GPU) is used to speed up the BEM computations to achieve the realtime performance. Next, instead of the GPU, a computer cluster is used. Results indicate that BEM is fast enough to provide for realtime graphics if biological organs are assumed to follow linear elastostatic material behavior. Although the present work does not conduct any simulation using nonlinear material models, results from using the linear elastostatic material model imply that it would be difficult to obtain realtime performance if highly nonlinear material models that properly characterize biological organs are used. Although the use of BEM for the simulation of biological organs is not new, the results presented in the present study are not found elsewhere in the literature.Comment: preprint, draft, 2 tables, 47 references, 7 files, Codes that can solve three dimensional linear elastostatic problems using constant boundary elements (of triangular shape) while ignoring body forces are provided as supplementary files; codes are distributed under the MIT License in three versions: i) MATLAB version ii) Fortran 90 version (sequential code) iii) Fortran 90 version (parallel code
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