Iontophoresis of the eye - a computational approach

Iontophoresis is an effective, non-invasive method of intraocular drug delivery based on electric current. However, it has many limitations that can be addressed by effective computational models based on both machine learning (a data-driven approach) and other artificial intelligence methods and techniques. To date, computational models using AI/ML are lacking, including for the iontophoresis mechanism itself. Their wider use would help facilitate the delivery of drugs to the eye, which remains a major challenge due to the multiple barriers in the eye. The aim of this paper is to explore the feasibility of developing a computational model for ocular iontophoresis using available AI methods and techniques.Jonoforeza jest skuteczną, nieinwazyjną metodą wewnątrzgałkowego podawania leków opartą na prądzie elektrycznym. Ma jednak wiele ograniczeń, które można rozwiązać za pomocą skutecznych modeli obliczeniowych opartych zarówno na uczeniu maszynowym (podejście oparte na danych), jak i innych metodach i technikach sztucznej inteligencji. Do tej pory brakuje modeli obliczeniowych wykorzystujących AI/ML, w tym dla samego mechanizmu jonoforezy. Ich szersze zastosowanie pomogłoby ułatwić dostarczanie leków do oczu, co pozostaje poważnym wyzwaniem ze względu na liczne bariery w oku. Celem artykułu jest zbadanie wykonalności opracowania modelu obliczeniowego dla jonoforezy ocznej przy użyciu dostępnych metod i technik sztucznej inteligencji

Principles of electrostimulation of the face and neck muscles - a medical and biocybernetic approach

The facial nerve has a tortuous and complex course from the parotid-cerebellar junction to various target sites, withindividually varied and complex branching patterns and connections to several other cranial nerves. This makes research-based computational models a key component of modern diagnostics and therapy, as well as patient monitoring and the design of devices to support the above-mentioned processes. To date, no good computational model has been proposed in this area and the concepts presented are in the preliminary research phase. The aim of this study is to develop guidelines for a computational model of electrostimulation of facial and neck muscles in order to improve diagnosis and therapy, but also for the future development of a virtual twin for eHealth.Nerw twarzowy ma kręty i złożony przebieg od połączenia ślinianki przyusznej i móżdżku do różnych miejsc docelowych, z indywidualnie zróżnicowanymi i złożonymi wzorcami rozgałęzień i połączeniami z kilkoma innymi nerwami czaszkowymi. Sprawia to, że modele obliczeniowe oparte na badaniach są kluczowym elementem nowoczesnej diagnostyki i terapii, a także monitorowania pacjentów i projektowania urządzeń wspierających wyżej wymienione procesy. Do tej pory nie zaproponowano dobrego modelu obliczeniowego w tym obszarze, a przedstawione koncepcje znajdują się we wstępnej fazie badań. Celem niniejszego badania jest opracowanie wytycznych dla modelu obliczeniowego elektrostymulacji mięśni twarzy i szyi w celu poprawy diagnostyki i terapii, ale także dla przyszłego rozwoju wirtualnego bliźniaka dla eZdrowi

Computational Intelligence in Healthcare

This book is a printed edition of the Special Issue Computational Intelligence in Healthcare that was published in Electronic

Computational Intelligence in Healthcare

The number of patient health data has been estimated to have reached 2314 exabytes by 2020. Traditional data analysis techniques are unsuitable to extract useful information from such a vast quantity of data. Thus, intelligent data analysis methods combining human expertise and computational models for accurate and in-depth data analysis are necessary. The technological revolution and medical advances made by combining vast quantities of available data, cloud computing services, and AI-based solutions can provide expert insight and analysis on a mass scale and at a relatively low cost. Computational intelligence (CI) methods, such as fuzzy models, artificial neural networks, evolutionary algorithms, and probabilistic methods, have recently emerged as promising tools for the development and application of intelligent systems in healthcare practice. CI-based systems can learn from data and evolve according to changes in the environments by taking into account the uncertainty characterizing health data, including omics data, clinical data, sensor, and imaging data. The use of CI in healthcare can improve the processing of such data to develop intelligent solutions for prevention, diagnosis, treatment, and follow-up, as well as for the analysis of administrative processes. The present Special Issue on computational intelligence for healthcare is intended to show the potential and the practical impacts of CI techniques in challenging healthcare applications

Application of fuzzy sets in data-to-text system

This PhD dissertation addresses the convergence of two distinct paradigms: fuzzy sets and natural language generation. The object of study is the integration of fuzzy set-derived techniques that model imprecision and uncertainty in human language into systems that generate textual information from numeric data, commonly known as data-to-text systems. This dissertation covers an extensive state of the art review, potential convergence points, two real data-to-text applications that integrate fuzzy sets (in the meteorology and learning analytics domains), and a model that encompasses the most relevant elements in the linguistic description of data discipline and provides a framework for building and integrating fuzzy set-based approaches into natural language generation/data-to-ext systems

Intelligent Sensors for Human Motion Analysis

The book, "Intelligent Sensors for Human Motion Analysis," contains 17 articles published in the Special Issue of the Sensors journal. These articles deal with many aspects related to the analysis of human movement. New techniques and methods for pose estimation, gait recognition, and fall detection have been proposed and verified. Some of them will trigger further research, and some may become the backbone of commercial systems

Computational Intelligence in Electromyography Analysis

Electromyography (EMG) is a technique for evaluating and recording the electrical activity produced by skeletal muscles. EMG may be used clinically for the diagnosis of neuromuscular problems and for assessing biomechanical and motor control deficits and other functional disorders. Furthermore, it can be used as a control signal for interfacing with orthotic and/or prosthetic devices or other rehabilitation assists. This book presents an updated overview of signal processing applications and recent developments in EMG from a number of diverse aspects and various applications in clinical and experimental research. It will provide readers with a detailed introduction to EMG signal processing techniques and applications, while presenting several new results and explanation of existing algorithms. This book is organized into 18 chapters, covering the current theoretical and practical approaches of EMG research

Biomechatronics: Harmonizing Mechatronic Systems with Human Beings

This eBook provides a comprehensive treatise on modern biomechatronic systems centred around human applications. A particular emphasis is given to exoskeleton designs for assistance and training with advanced interfaces in human-machine interaction. Some of these designs are validated with experimental results which the reader will find very informative as building-blocks for designing such systems. This eBook will be ideally suited to those researching in biomechatronic area with bio-feedback applications or those who are involved in high-end research on manmachine interfaces. This may also serve as a textbook for biomechatronic design at post-graduate level

Proceedings of the 1st Doctoral Consortium at the European Conference on Artificial Intelligence (DC-ECAI 2020)

1st Doctoral Consortium at the European Conference on Artificial Intelligence (DC-ECAI 2020), 29-30 August, 2020 Santiago de Compostela, SpainThe DC-ECAI 2020 provides a unique opportunity for PhD students, who are close to finishing their doctorate research, to interact with experienced researchers in the field. Senior members of the community are assigned as mentors for each group of students based on the student’s research or similarity of research interests. The DC-ECAI 2020, which is held virtually this year, allows students from all over the world to present their research and discuss their ongoing research and career plans with their mentor, to do networking with other participants, and to receive training and mentoring about career planning and career option

Affective Computing for Emotion Detection using Vision and Wearable Sensors

The research explores the opportunities, challenges, limitations, and presents advancements in computing that relates to, arises from, or deliberately influences emotions (Picard, 1997). The field is referred to as Affective Computing (AC) and is expected to play a major role in the engineering and development of computationally and cognitively intelligent systems, processors and applications in the future. Today the field of AC is bolstered by the emergence of multiple sources of affective data and is fuelled on by developments under various Internet of Things (IoTs) projects and the fusion potential of multiple sensory affective data streams. The core focus of this thesis involves investigation into whether the sensitivity and specificity (predictive performance) of AC, based on the fusion of multi-sensor data streams, is fit for purpose? Can such AC powered technologies and techniques truly deliver increasingly accurate emotion predictions of subjects in the real world? The thesis begins by presenting a number of research justifications and AC research questions that are used to formulate the original thesis hypothesis and thesis objectives. As part of the research conducted, a detailed state of the art investigations explored many aspects of AC from both a scientific and technological perspective. The complexity of AC as a multi-sensor, multi-modality, data fusion problem unfolded during the state of the art research and this ultimately led to novel thinking and origination in the form of the creation of an AC conceptualised architecture that will act as a practical and theoretical foundation for the engineering of future AC platforms and solutions. The AC conceptual architecture developed as a result of this research, was applied to the engineering of a series of software artifacts that were combined to create a prototypical AC multi-sensor platform known as the Emotion Fusion Server (EFS) to be used in the thesis hypothesis AC experimentation phases of the research. The thesis research used the EFS platform to conduct a detailed series of AC experiments to investigate if the fusion of multiple sensory sources of affective data from sensory devices can significantly increase the accuracy of emotion prediction by computationally intelligent means. The research involved conducting numerous controlled experiments along with the statistical analysis of the performance of sensors for the purposes of AC, the findings of which serve to assess the feasibility of AC in various domains and points to future directions for the AC field. The AC experiments data investigations conducted in relation to the thesis hypothesis used applied statistical methods and techniques, and the results, analytics and evaluations are presented throughout the two thesis research volumes. The thesis concludes by providing a detailed set of formal findings, conclusions and decisions in relation to the overarching research hypothesis on the sensitivity and specificity of the fusion of vision and wearables sensor modalities and offers foresights and guidance into the many problems, challenges and projections for the AC field into the future