The head-modifier principle and multilingual term extraction

Advances in Language Engineering may be dependent on theoretical principles originating from linguistics since both share a common object of enquiry, natural language structures. We outline an approach to term extraction that rests on theoretical claims about the structure of words. We use the structural properties of compound words to specifically elicit the sets of terms defined by type hierarchies such as hyponymy and meronymy. The theoretical claims revolve around the head-modifier principle which determines the formation of a major class of compounds. Significantly it has been suggested that the principle operates in languages other than English. To demonstrate the extendibility of our approach beyond English, we present a case study of term extraction in Chinese, a language whose written form is the vehicle of communication for over 1.3 billion language users, and therefore has great significance for the development of language engineering technologies

An evaluation of thermodynamic models for the prediction of drug and drug-like molecule solubility in organic solvents

Prediction of solubility of active pharmaceutical ingredients (API) in different solvents is one of the main issue for crystallization process design. Experimental determination is not always possible because of the small amount of product available in the early stages of a drug development. Thus, one interesting perspective is the use of thermodynamic models, which are usually employed for predicting the activity coefficients in case of Vapour–Liquid equilibria or Liquid–Liquid equilibria (VLE or LLE). The choice of the best thermodynamic model for Solid–Liquid equilibria (SLE) is not an easy task as most of them are not meant particularly for this. In this paper, several models are tested for the solubility prediction of five drugs or drug-like molecules: Ibuprofen, Acetaminophen, Benzoic acid, Salicylic acid and 4-aminobenzoic acid, and another molecule, anthracene, a rather simple molecule. The performance of predictive (UNIFAC, UNIFAC mod., COSMO-SAC) and semi-predictive (NRTL-SAC) models are compared and discussed according to the functional groups of the molecules and the selected solvents. Moreover, the model errors caused by solid state property uncertainties are taken into account. These errors are indeed not negligible when accurate quantitative predictions want to be performed. It was found that UNIFAC models give the best results and could be an useful method for rapid solubility estimations of an API in various solvents. This model achieves the order of magnitude of the experimental solubility and can predict in which solvents the drug will be very soluble, soluble or not soluble. In addition, predictions obtained with NRTL-SAC model are also in good agreement with the experiments, but in that case the relevance of the results is strongly dependent on the model parameters regressed from solubility data in single and mixed solvents. However, this is a very interesting model for quick estimations like UNIFAC models. Finally, COSMO-SAC needs more developments to increase its accuracy especially when hydrogen bonding is involved. In that case, the predicted solubility is always overestimated from two to three orders of magnitude. Considering the use of the most accurate equilibrium equation involving the ΔCp term, no benefits were found for drug predictions as the models are still too inaccurate. However, in function of the molecules and their solid thermodynamic properties, the ΔCp term can be neglected and will not have a great impact on the results

Commented Translation of Technical Text

Tato bakalářská práce se zaměřuje na překlad učebního textu z oblasti elektrotechniky. Práce má za cíl přeložit a analyzovat odborný učební text a je rozdělena na tři hlavní části. V teoretické části je uvedena zejména charakteristika odborného a učebního stylu, typy překladatelských postupů, překladatelské transformace a funkční perspektiva větná. Praktická část předkládá anglický překlad úryvku ze skript a analytická část má za cíl analyzovat problémy, které se vyskytly při překladu a zhodnotit charakteristické znaky odborného učebního stylu založené na analýze tohoto překladu.This bachelor thesis deals with the translation of a didactic text from the electrical engineering field. The work aims to translate and analyze a didactic technical text and is divided into three main parts. The theoretical part introduces namely the characteristics of technical style and didactic style, types of translation procedures, translation transformation and the functional sentence perspective. The practical part presents an English translation of an excerpt taken from a university textbook and the analytic part aims presenting the problems that occurred during the translation process and the assessment of the characteristics of technical didactic style based on this translation analysis.

Ultrafast harmonic mode-locking of monolithic compound-cavity laser diodes incorporating photonic-bandgap reflectors

We present the first demonstration of reproducible harmonic mode-locked operation from a novel design of monolithic semiconductor laser comprising a compound cavity formed by a 1-D photonic-bandgap (PBG) mirror. Mode-locking (ML) is achieved at a harmonic of the fundamental round-trip frequency with pulse repetition rates from 131 GHz up to a record high frequency of 2.1 THz. The devices are fabricated from GaAs-Al-GaAs material emitting at a wavelength of 860 nm and incorporate two gain sections with an etched PBG reflector between them, and a saturable absorber section. Autocorrelation studies are reported which allow the device behavior for different ML frequencies, compound cavity ratios, and type and number of intra-cavity reflectors to be analyzed. The highly reflective PBG microstructures are shown to be essential for subharmonic-free ML operation of the high-frequency devices. We have also demonstrated that the single PBG reflector can be replaced by two separate features with lower optical loss. These lasers may find applications in terahertz; imaging, medicine, ultrafast optical links, and atmospheric sensing