54,884 research outputs found

    The learning technologies of the future: technologies that learn?

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    Higher Education Institutions (HEIs) operate in a borderless and complex environment, abundant in potentially useful information. The Creating Academic Learning Futures (CALF) research project, carried out in partnership by the University of Leicester and University College Falmouth in the UK, involves the development of approaches and tools for structuring and filtering information, in order to facilitate institutional decision-making in participative and creative ways. One of the aims of the CALF project is to involve students in creating and exploring a variety of plausible ‘alternative futures’ for learning and teaching technologies in higher education. This paper discusses some of the issues that are emerging in the course of the research process and presents ideas for the future, grounded in and emergent from ‘student voices’ from the CALF research project. Students expected the technologies of the near future to enable them to become co-creators in their own education processes. The future scenarios imagined the rise of learning technologies which instead of becoming outdated with use, become more valuable as more user-generated content is invested, technologies which are truly learning in that they learn about their users and constantly morph/adapt to their users’ needs. Finally, increasing virtualisation was a recurrent theme across most student-generated scenarios. The paper concludes with a discussion of some of the strengths and limitations of using technologies for involving students in creative activities for generating future scenarios for higher education. The technologies used by the project enabled collaborative creative thinking across a broader spectrum of possibilities about the relationship between the present and the future of higher education

    Extraction of Transcript Diversity from Scientific Literature

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    Transcript diversity generated by alternative splicing and associated mechanisms contributes heavily to the functional complexity of biological systems. The numerous examples of the mechanisms and functional implications of these events are scattered throughout the scientific literature. Thus, it is crucial to have a tool that can automatically extract the relevant facts and collect them in a knowledge base that can aid the interpretation of data from high-throughput methods. We have developed and applied a composite text-mining method for extracting information on transcript diversity from the entire MEDLINE database in order to create a database of genes with alternative transcripts. It contains information on tissue specificity, number of isoforms, causative mechanisms, functional implications, and experimental methods used for detection. We have mined this resource to identify 959 instances of tissue-specific splicing. Our results in combination with those from EST-based methods suggest that alternative splicing is the preferred mechanism for generating transcript diversity in the nervous system. We provide new annotations for 1,860 genes with the potential for generating transcript diversity. We assign the MeSH term “alternative splicing” to 1,536 additional abstracts in the MEDLINE database and suggest new MeSH terms for other events. We have successfully extracted information about transcript diversity and semiautomatically generated a database, LSAT, that can provide a quantitative understanding of the mechanisms behind tissue-specific gene expression. LSAT (Literature Support for Alternative Transcripts) is publicly available at http://www.bork.embl.de/LSAT/

    A Conflict-Resilient Lock-Free Calendar Queue for Scalable Share-Everything PDES Platforms

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    Emerging share-everything Parallel Discrete Event Simulation (PDES) platforms rely on worker threads fully sharing the workload of events to be processed. These platforms require efficient event pool data structures enabling high concurrency of extraction/insertion operations. Non-blocking event pool algorithms are raising as promising solutions for this problem. However, the classical non-blocking paradigm leads concurrent conflicting operations, acting on a same portion of the event pool data structure, to abort and then retry. In this article we present a conflict-resilient non-blocking calendar queue that enables conflicting dequeue operations, concurrently attempting to extract the minimum element, to survive, thus improving the level of scalability of accesses to the hot portion of the data structure---namely the bucket to which the current locality of the events to be processed is bound. We have integrated our solution within an open source share-everything PDES platform and report the results of an experimental analysis of the proposed concurrent data structure compared to some literature solutions

    Towards joint decoding of binary Tardos fingerprinting codes

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    The class of joint decoder of probabilistic fingerprinting codes is of utmost importance in theoretical papers to establish the concept of fingerprint capacity. However, no implementation supporting a large user base is known to date. This article presents an iterative decoder which is, as far as we are aware of, the first practical attempt towards joint decoding. The discriminative feature of the scores benefits on one hand from the side-information of previously accused users, and on the other hand, from recently introduced universal linear decoders for compound channels. Neither the code construction nor the decoder make precise assumptions about the collusion (size or strategy). The extension to incorporate soft outputs from the watermarking layer is straightforward. An extensive experimental work benchmarks the very good performance and offers a clear comparison with previous state-of-the-art decoders.Comment: submitted to IEEE Trans. on Information Forensics and Security. - typos corrected, one new plot, references added about ECC based fingerprinting code

    The integrated use of enterprise and system dynamics modelling techniques in support of business decisions

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    Enterprise modelling techniques support business process re-engineering by capturing existing processes and based on perceived outputs, support the design of future process models capable of meeting enterprise requirements. System dynamics modelling tools on the other hand are used extensively for policy analysis and modelling aspects of dynamics which impact on businesses. In this paper, the use of enterprise and system dynamics modelling techniques has been integrated to facilitate qualitative and quantitative reasoning about the structures and behaviours of processes and resource systems used by a Manufacturing Enterprise during the production of composite bearings. The case study testing reported has led to the specification of a new modelling methodology for analysing and managing dynamics and complexities in production systems. This methodology is based on a systematic transformation process, which synergises the use of a selection of public domain enterprise modelling, causal loop and continuous simulationmodelling techniques. The success of the modelling process defined relies on the creation of useful CIMOSA process models which are then converted to causal loops. The causal loop models are then structured and translated to equivalent dynamic simulation models using the proprietary continuous simulation modelling tool iThink

    A Non-Blocking Priority Queue for the Pending Event Set

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    The large diffusion of shared-memory multi-core machines has impacted the way Parallel Discrete Event Simulation (PDES) engines are built. While they were originally conceived as data-partitioned platforms, where each thread is in charge of managing a subset of simulation objects, nowadays the trend is to shift towards share-everything settings. In this scenario, any thread can (in principle) take care of CPU-dispatching pending events bound to whichever simulation object, which helps to fully share the load across the available CPU-cores. Hence, a fundamental aspect to be tackled is to provide an efficient globally-shared pending events’ set from which multiple worker threads can concurrently extract events to be processed, and into which they can concurrently insert new produced events to be processed in the future. To cope with this aspect, we present the design and implementation of a concurrent non-blocking pending events’ set data structure, which can be seen as a variant of a classical calendar queue. Early experimental data collected with a synthetic stress test are reported, showing excellent scalability of our proposal on a machine equipped with 32 CPU-cores
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