255 research outputs found

    Managing healthcare transformation towards P5 medicine (Published in Frontiers in Medicine)

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    Health and social care systems around the world are facing radical organizational, methodological and technological paradigm changes to meet the requirements for improving quality and safety of care as well as efficiency and efficacy of care processes. In this they’re trying to manage the challenges of ongoing demographic changes towards aging, multi-diseased societies, development of human resources, a health and social services consumerism, medical and biomedical progress, and exploding costs for health-related R&D as well as health services delivery. Furthermore, they intend to achieve sustainability of global health systems by transforming them towards intelligent, adaptive and proactive systems focusing on health and wellness with optimized quality and safety outcomes. The outcome is a transformed health and wellness ecosystem combining the approaches of translational medicine, 5P medicine (personalized, preventive, predictive, participative precision medicine) and digital health towards ubiquitous personalized health services realized independent of time and location. It considers individual health status, conditions, genetic and genomic dispositions in personal social, occupational, environmental and behavioural context, thus turning health and social care from reactive to proactive. This requires the advancement communication and cooperation among the business actors from different domains (disciplines) with different methodologies, terminologies/ontologies, education, skills and experiences from data level (data sharing) to concept/knowledge level (knowledge sharing). The challenge here is the understanding and the formal as well as consistent representation of the world of sciences and practices, i.e. of multidisciplinary and dynamic systems in variable context, for enabling mapping between the different disciplines, methodologies, perspectives, intentions, languages, etc. Based on a framework for dynamically, use-case-specifically and context aware representing multi-domain ecosystems including their development process, systems, models and artefacts can be consistently represented, harmonized and integrated. The response to that problem is the formal representation of health and social care ecosystems through an system-oriented, architecture-centric, ontology-based and policy-driven model and framework, addressing all domains and development process views contributing to the system and context in question. Accordingly, this Research Topic would like to address this change towards 5P medicine. Specifically, areas of interest include, but are not limited: • A multidisciplinary approach to the transformation of health and social systems • Success factors for sustainable P5 ecosystems • AI and robotics in transformed health ecosystems • Transformed health ecosystems challenges for security, privacy and trust • Modelling digital health systems • Ethical challenges of personalized digital health • Knowledge representation and management of transformed health ecosystems Table of Contents: 04 Editorial: Managing healthcare transformation towards P5 medicine Bernd Blobel and Dipak Kalra 06 Transformation of Health and Social Care Systems—An Interdisciplinary Approach Toward a Foundational Architecture Bernd Blobel, Frank Oemig, Pekka Ruotsalainen and Diego M. Lopez 26 Transformed Health Ecosystems—Challenges for Security, Privacy, and Trust Pekka Ruotsalainen and Bernd Blobel 36 Success Factors for Scaling Up the Adoption of Digital Therapeutics Towards the Realization of P5 Medicine Alexandra Prodan, Lucas Deimel, Johannes Ahlqvist, Strahil Birov, Rainer Thiel, Meeri Toivanen, Zoi Kolitsi and Dipak Kalra 49 EU-Funded Telemedicine Projects – Assessment of, and Lessons Learned From, in the Light of the SARS-CoV-2 Pandemic Laura Paleari, Virginia Malini, Gabriella Paoli, Stefano Scillieri, Claudia Bighin, Bernd Blobel and Mauro Giacomini 60 A Review of Artificial Intelligence and Robotics in Transformed Health Ecosystems Kerstin Denecke and Claude R. Baudoin 73 Modeling digital health systems to foster interoperability Frank Oemig and Bernd Blobel 89 Challenges and solutions for transforming health ecosystems in low- and middle-income countries through artificial intelligence Diego M. López, Carolina Rico-Olarte, Bernd Blobel and Carol Hullin 111 Linguistic and ontological challenges of multiple domains contributing to transformed health ecosystems Markus Kreuzthaler, Mathias Brochhausen, Cilia Zayas, Bernd Blobel and Stefan Schulz 126 The ethical challenges of personalized digital health Els Maeckelberghe, Kinga Zdunek, Sara Marceglia, Bobbie Farsides and Michael Rigb

    Facilitating Information Access for Heterogeneous Data Across Many Languages

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    Information access, which enables people to identify, retrieve, and use information freely and effectively, has attracted interest from academia and industry. Systems for document retrieval and question answering have helped people access information in powerful and useful ways. Recently, natural language technologies based on neural network have been applied to various tasks for information access. Specifically, transformer-based pre-trained models have pushed tasks such as document and passage retrieval to new state-of-the-art effectiveness. (1) Most of the research has focused on helping people access passages and documents on the web. However, there is abundant information stored in other formats such as semi-structured tables and domain-specific relational databases in companies. Development of the models and frameworks that support access information from these data formats is also essential. (2) Moreover, most of the advances in information access research are based on English, leaving other languages less explored. It is insufficient and inequitable in our globalized and connected world to serve only speakers of English. In this thesis, we explore and develop models and frameworks that could alleviate the aforementioned challenges. This dissertation consists of three parts. We begin with a discussion on developing models designed for accessing data in formats other than passages and documents. We mainly focus on two data formats, namely semi-structured tables and relational databases. In the second part, we discuss methods that can enhance the user experience for non-English speakers when using information access systems. Specifically, we first introduce model development for multilingual knowledge graph integration, which can benefit many information access applications such as cross-lingual question answering systems and other knowledge-driven cross-lingual NLP applications. We further focus on multilingual document dense retrieval and reranking that boost the effectiveness of search engines for non-English information access. Last but not least, we take a step further based on the aforementioned two parts by investigating models and frameworks that can facilitate non-English speakers to access structured data. In detail, we present cross-lingual Text-to-SQL semantic parsing systems that enable non-English speakers to query relational databases with queries in their languages

    Semantic wikis as flexible database interfaces for biomedical applications

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    Several challenges prevent extracting knowledge from biomedical resources, including data heterogeneity and the difficulty to obtain and collaborate on data and annotations by medical doctors. Therefore, flexibility in their representation and interconnection is required; it is also essential to be able to interact easily with such data. In recent years, semantic tools have been developed: semantic wikis are collections of wiki pages that can be annotated with properties and so combine flexibility and expressiveness, two desirable aspects when modeling databases, especially in the dynamic biomedical domain. However, semantics and collaborative analysis of biomedical data is still an unsolved challenge. The aim of this work is to create a tool for easing the design and the setup of semantic databases and to give the possibility to enrich them with biostatistical applications. As a side effect, this will also make them reproducible, fostering their application by other research groups. A command-line software has been developed for creating all structures required by Semantic MediaWiki. Besides, a way to expose statistical analyses as R Shiny applications in the interface is provided, along with a facility to export Prolog predicates for reasoning with external tools. The developed software allowed to create a set of biomedical databases for the Neuroscience Department of the University of Padova in a more automated way. They can be extended with additional qualitative and statistical analyses of data, including for instance regressions, geographical distribution of diseases, and clustering. The software is released as open source-code and published under the GPL-3 license at https://github.com/mfalda/tsv2swm

    WiFi-Based Human Activity Recognition Using Attention-Based BiLSTM

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    Recently, significant efforts have been made to explore human activity recognition (HAR) techniques that use information gathered by existing indoor wireless infrastructures through WiFi signals without demanding the monitored subject to carry a dedicated device. The key intuition is that different activities introduce different multi-paths in WiFi signals and generate different patterns in the time series of channel state information (CSI). In this paper, we propose and evaluate a full pipeline for a CSI-based human activity recognition framework for 12 activities in three different spatial environments using two deep learning models: ABiLSTM and CNN-ABiLSTM. Evaluation experiments have demonstrated that the proposed models outperform state-of-the-art models. Also, the experiments show that the proposed models can be applied to other environments with different configurations, albeit with some caveats. The proposed ABiLSTM model achieves an overall accuracy of 94.03%, 91.96%, and 92.59% across the 3 target environments. While the proposed CNN-ABiLSTM model reaches an accuracy of 98.54%, 94.25% and 95.09% across those same environments

    Development of linguistic linked open data resources for collaborative data-intensive research in the language sciences

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    Making diverse data in linguistics and the language sciences open, distributed, and accessible: perspectives from language/language acquistiion researchers and technical LOD (linked open data) researchers. This volume examines the challenges inherent in making diverse data in linguistics and the language sciences open, distributed, integrated, and accessible, thus fostering wide data sharing and collaboration. It is unique in integrating the perspectives of language researchers and technical LOD (linked open data) researchers. Reporting on both active research needs in the field of language acquisition and technical advances in the development of data interoperability, the book demonstrates the advantages of an international infrastructure for scholarship in the field of language sciences. With contributions by researchers who produce complex data content and scholars involved in both the technology and the conceptual foundations of LLOD (linguistics linked open data), the book focuses on the area of language acquisition because it involves complex and diverse data sets, cross-linguistic analyses, and urgent collaborative research. The contributors discuss a variety of research methods, resources, and infrastructures. Contributors Isabelle Barrière, Nan Bernstein Ratner, Steven Bird, Maria Blume, Ted Caldwell, Christian Chiarcos, Cristina Dye, Suzanne Flynn, Claire Foley, Nancy Ide, Carissa Kang, D. Terence Langendoen, Barbara Lust, Brian MacWhinney, Jonathan Masci, Steven Moran, Antonio Pareja-Lora, Jim Reidy, Oya Y. Rieger, Gary F. Simons, Thorsten Trippel, Kara Warburton, Sue Ellen Wright, Claus Zin

    When Children Draw Gods

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    This open access book explores how children draw god. It looks at children’s drawings collected in a large variety of cultural and religious traditions. Coverage demonstrates the richness of drawing as a method for studying representations of the divine. In the process, it also contributes to our understanding of this concept, its origins, and its development. This intercultural work brings together scholars from different disciplines and countries, including Switzerland, Japan, Russia, Iran, Brazil, and the Netherlands. It does more than share the results of their research and analysis. The volume also critically examines the contributions and limitations of this methodology. In addition, it also reflects on the new empirical and theoretical perspectives within the broader framework of the study of this concept. The concept of god is one of the most difficult to grasp. This volume offers new insights by focusing on the many different ways children depict god throughout the world. Readers will discover the importance of spatial imagery and color choices in drawings of god. They will also learn about how the divine's emotional expression correlates to age, gender, and religiosity as well as strategies used by children who are prohibited from representing their god

    AN EMPIRICAL COMPARISON OF NEO4J AND TIGERGRAPH DATABASES FOR NETWORK CENTRALITY

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    Graph databases have recently gained a lot of attention in areas where the relationships between data and the data itself are equally important, like the semantic web, social networks, and biological networks. A graph database is simply a database designed to store, query, and modify graphs. Recently, several graph database models have been developed. The goal of this research is to evaluate the performance of the two most popular graph databases, Neo4j and TigerGraph, for network centrality metrics including degree centrality, betweenness centrality, closeness centrality, eigenvector centrality, and PageRank. We applied those metrics to a set of real-world networks in both graph databases to see their performance. Experimental results show Neo4j outperforms TigerGraph for computing the centrality metrics used in this study, but TigerGraph performs better during the data loading phase

    Systematic Approaches for Telemedicine and Data Coordination for COVID-19 in Baja California, Mexico

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    Conference proceedings info: ICICT 2023: 2023 The 6th International Conference on Information and Computer Technologies Raleigh, HI, United States, March 24-26, 2023 Pages 529-542We provide a model for systematic implementation of telemedicine within a large evaluation center for COVID-19 in the area of Baja California, Mexico. Our model is based on human-centric design factors and cross disciplinary collaborations for scalable data-driven enablement of smartphone, cellular, and video Teleconsul-tation technologies to link hospitals, clinics, and emergency medical services for point-of-care assessments of COVID testing, and for subsequent treatment and quar-antine decisions. A multidisciplinary team was rapidly created, in cooperation with different institutions, including: the Autonomous University of Baja California, the Ministry of Health, the Command, Communication and Computer Control Center of the Ministry of the State of Baja California (C4), Colleges of Medicine, and the College of Psychologists. Our objective is to provide information to the public and to evaluate COVID-19 in real time and to track, regional, municipal, and state-wide data in real time that informs supply chains and resource allocation with the anticipation of a surge in COVID-19 cases. RESUMEN Proporcionamos un modelo para la implementación sistemática de la telemedicina dentro de un gran centro de evaluación de COVID-19 en el área de Baja California, México. Nuestro modelo se basa en factores de diseño centrados en el ser humano y colaboraciones interdisciplinarias para la habilitación escalable basada en datos de tecnologías de teleconsulta de teléfonos inteligentes, celulares y video para vincular hospitales, clínicas y servicios médicos de emergencia para evaluaciones de COVID en el punto de atención. pruebas, y para el tratamiento posterior y decisiones de cuarentena. Rápidamente se creó un equipo multidisciplinario, en cooperación con diferentes instituciones, entre ellas: la Universidad Autónoma de Baja California, la Secretaría de Salud, el Centro de Comando, Comunicaciones y Control Informático. de la Secretaría del Estado de Baja California (C4), Facultades de Medicina y Colegio de Psicólogos. Nuestro objetivo es proporcionar información al público y evaluar COVID-19 en tiempo real y rastrear datos regionales, municipales y estatales en tiempo real que informan las cadenas de suministro y la asignación de recursos con la anticipación de un aumento de COVID-19. 19 casos.ICICT 2023: 2023 The 6th International Conference on Information and Computer Technologieshttps://doi.org/10.1007/978-981-99-3236-

    Structural Summarization of Semantic Graphs Using Quotients

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    Graph summarization is the process of computing a compact version of an input graph while preserving chosen features of its structure. We consider semantic graphs where the features include edge labels and label sets associated with a vertex. Graph summaries are typically much smaller than the original graph. Applications that depend on the preserved features can perform their tasks on the summary, but much faster or with less memory overhead, while producing the same outcome as if they were applied on the original graph. In this survey, we focus on structural summaries based on quotients that organize vertices in equivalence classes of shared features. Structural summaries are particularly popular for semantic graphs and have the advantage of defining a precise graph-based output. We consider approaches and algorithms for both static and temporal graphs. A common example of quotient-based structural summaries is bisimulation, and we discuss this in detail. While there exist other surveys on graph summarization, to the best of our knowledge, we are the first to bring in a focused discussion on quotients, bisimulation, and their relation. Furthermore, structural summarization naturally connects well with formal logic due to the discrete structures considered. We complete the survey with a brief description of approaches beyond structural summaries
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