A Predictive Model for Assessment of Successful Outcome in Posterior Spinal Fusion Surgery

Background: Low back pain is a common problem in many people. Neurosurgeons recommend posterior spinal fusion (PSF) surgery as one of the therapeutic strategies to the patients with low back pain. Due to the high risk of this type of surgery and the critical importance of making the right decision, accurate prediction of the surgical outcome is one of the main concerns for the neurosurgeons.Methods: In this study, 12 types of multi-layer perceptron (MLP) networks and 66 radial basis function (RBF) networks as the types of artificial neural network methods and a logistic regression (LR) model created and compared to predict the satisfaction with PSF surgery as one of the most well-known spinal surgeries.Results: The most important clinical and radiologic features as twenty-seven factors for 480 patients (150 males, 330 females; mean age 52.32 ± 8.39 years) were considered as the model inputs that included: age, sex, type of disorder, duration of symptoms, job, walking distance without pain (WDP), walking distance without sensory (WDS) disorders, visual analog scale (VAS) scores, Japanese Orthopaedic Association (JOA) score, diabetes, smoking, knee pain (KP), pelvic pain (PP), osteoporosis, spinal deformity and etc. The indexes such as receiver operating characteristic–area under curve (ROC-AUC), positive predictive value, negative predictive value and accuracy calculated to determine the best model. Postsurgical satisfaction was 77.5% at 6 months follow-up. The patients divided into the training, testing, and validation data sets.Conclusion: The findings showed that the MLP model performed better in comparison with RBF and LR models for prediction of PSF surgery.Keywords: Posterior spinal fusion surgery (PSF); Prediction, Surgical satisfaction; Multi-layer perceptron (MLP); Logistic regression (LR) (PDF) A Predictive Model for Assessment of Successful Outcome in Posterior Spinal Fusion Surgery. Available from: https://www.researchgate.net/publication/325679954_A_Predictive_Model_for_Assessment_of_Successful_Outcome_in_Posterior_Spinal_Fusion_Surgery [accessed Jul 11 2019].Peer reviewe

A Comparison of Intensive Care Unit Mortality Prediction Models through the Use of Data Mining Techniques

OBJECTIVES: The intensive care environment generates a wealth of critical care data suited to developing a well-calibrated prediction tool. This study was done to develop an intensive care unit (ICU) mortality prediction model built on University of Kentucky Hospital (UKH)\u27s data and to assess whether the performance of various data mining techniques, such as the artificial neural network (ANN), support vector machine (SVM) and decision trees (DT), outperform the conventional logistic regression (LR) statistical model. METHODS: The models were built on ICU data collected regarding 38,474 admissions to the UKH between January 1998 and September 2007. The first 24 hours of the ICU admission data were used, including patient demographics, admission information, physiology data, chronic health items, and outcome information. RESULTS: Only 15 study variables were identified as significant for inclusion in the model development. The DT algorithm slightly outperformed (AUC, 0.892) the other data mining techniques, followed by the ANN (AUC, 0.874), and SVM (AUC, 0.876), compared to that of the APACHE III performance (AUC, 0.871). CONCLUSIONS: With fewer variables needed, the machine learning algorithms that we developed were proven to be as good as the conventional APACHE III prediction

Comparing Performances of Logistic Regression, Classification & Regression Trees and Artificial Neural Networks for Predicting Albuminuria in Type 2 Diabetes Mellitus

In this study, performances of classification methods were compared in order to predict the presence of albuminuria in type 2 diabetes mellitus patients. A retrospective analysis was performed in 266 subjects. We compared performances of logistic regression (LR), classification and regression trees (C&RT) and two artificial neural networks algorithms. Predictor variables were gender, urine creatinine, weight, blood urea, serum albumin, age, creatinine clearance, fasting plasma glucose, post-prandial plasma glucose, and HbA1c. For validation set, the best classification accuracy (84.85%), sensitivity (68.0%) and the highest Youden index (0.63) was found in the MLP model but the specificity was 95.12%. Additionally, the specificity of all the models was close to each other. For whole data set the results were found as 84.21%, 53.95%, 0.50 and 96.32% respectively. Consequently, the model had the highest predictive capability to predict the presence of albuminuria was MLP. According to this model, blood urea and serum albumin were the most important variables for predicting the albuminuria. On the basis of these considerations, we suggest that data should be better explored and processed by high performance modeling methods. Researchers should avoid assessment of data by using only one method in future studies focusing on albuminuria in type 2 diabetes mellitus patients or any other clinical condition

Involving machine learning techniques in heart disease diagnosis: a performance analysis

Artificial intelligence is a science that is growing at a tremendous speed every day and has become an essential part of many domains, including the medical domain. Therefore, countless artificial intelligence applications can be seen in the medical domain at various levels, which are employed to enhance early diagnosis and prediction and reduce the risks associated with many diseases, including heart diseases. In this article, machine learning techniques (logistic regression, random forest, artificial neural network, support vector machines, and k-nearest neighbors) are utilized to diagnose heart disease from the Cleveland Clinic dataset got from the University of California Irvine machine learning (UCL) repository and Kaggle platform then create a comparison between the performance of these techniques. In addition, some literature related to machine learning and deep learning techniques that aim to provide reasonable solutions in monitoring, detecting, diagnosing, and predicting heart disease and how these technologies assist in making health decisions are reviewed. Ten studies are selected and summarized by the authors published between 2017 and 2022 are illustrated. After executing a series of tests, it is seen that the most profitable performance in diagnosing heart disease is the support vector machines, with a diagnostic accuracy of 96%. This article has concluded that these techniques play a significant and influential role in assisting physicians and health care workers in analyzing heart patients' data, making health decisions, and saving patients' lives

Hybrid System of Tiered Multivariate Analysis and Artificial Neural Network for Coronary Heart Disease Diagnosis

Improved system performance diagnosis of coronary heart disease becomes an important topic in research for several decades. One improvement would be done by features selection, so only the attributes that influence is used in the diagnosis system using data mining algorithms. Unfortunately, the most feature selection is done with the assumption has provided all the necessary attributes, regardless of the stage of obtaining the attribute, and cost required. This research proposes a hybrid model system for diagnosis of coronary heart disease. System diagnosis preceded the feature selection process, using tiered multivariate analysis. The analytical method used is logistic regression. The next stage, the classification by using multi-layer perceptron neural network. Based on test results, system performance proposed value for accuracy 86.3%, sensitivity 84.80%, specificity 88.20%, positive prediction value (PPV) 90.03%, negative prediction value (NPV) 81.80%, accuracy 86,30%  and area under the curve (AUC) of 92.1%. The performance of a diagnosis using a combination attributes of risk factors,symptoms and exercise ECG. The conclusion that can be drawn is that the proposed diagnosis system capable of delivering performance in the very good category, with a number of attributes that are not a lot of checks and a relatively low cost

Using Combined Descriptive and Predictive Methods of Data Mining for Coronary Artery Disease Prediction: a Case Study Approach

Heart disease is one of the major causes of morbidity in the world. Currently, large proportions of healthcare data are not processed properly, thus, failing to be effectively used for decision making purposes. The risk of heart disease may be predicted via investigation of heart disease risk factors coupled with data mining knowledge. This paper presents a model developed using combined descriptive and predictive techniques of data mining that aims to aid specialists in the healthcare system to effectively predict patients with Coronary Artery Disease (CAD). To achieve this objective, some clustering and classification techniques are used. First, the number of clusters are determined using clustering indexes. Next, some types of decision tree methods and Artificial Neural Network (ANN) are applied to each cluster in order to predict CAD patients. Finally, results obtained show that the C&RT decision tree method performs best on all data used in this study with 0.074 error. All data used in this study are real and are collected from a heart clinic database