CLAD: A Complex and Long Activities Dataset with Rich Crowdsourced Annotations

This paper introduces a novel activity dataset which exhibits real-life and diverse scenarios of complex, temporally-extended human activities and actions. The dataset presents a set of videos of actors performing everyday activities in a natural and unscripted manner. The dataset was recorded using a static Kinect 2 sensor which is commonly used on many robotic platforms. The dataset comprises of RGB-D images, point cloud data, automatically generated skeleton tracks in addition to crowdsourced annotations. Furthermore, we also describe the methodology used to acquire annotations through crowdsourcing. Finally some activity recognition benchmarks are presented using current state-of-the-art techniques. We believe that this dataset is particularly suitable as a testbed for activity recognition research but it can also be applicable for other common tasks in robotics/computer vision research such as object detection and human skeleton tracking

Empirical Methodology for Crowdsourcing Ground Truth

The process of gathering ground truth data through human annotation is a major bottleneck in the use of information extraction methods for populating the Semantic Web. Crowdsourcing-based approaches are gaining popularity in the attempt to solve the issues related to volume of data and lack of annotators. Typically these practices use inter-annotator agreement as a measure of quality. However, in many domains, such as event detection, there is ambiguity in the data, as well as a multitude of perspectives of the information examples. We present an empirically derived methodology for efficiently gathering of ground truth data in a diverse set of use cases covering a variety of domains and annotation tasks. Central to our approach is the use of CrowdTruth metrics that capture inter-annotator disagreement. We show that measuring disagreement is essential for acquiring a high quality ground truth. We achieve this by comparing the quality of the data aggregated with CrowdTruth metrics with majority vote, over a set of diverse crowdsourcing tasks: Medical Relation Extraction, Twitter Event Identification, News Event Extraction and Sound Interpretation. We also show that an increased number of crowd workers leads to growth and stabilization in the quality of annotations, going against the usual practice of employing a small number of annotators.Comment: in publication at the Semantic Web Journa

Spectral imaging in preclinical research and clinical pathology.

Spectral imaging methods are attracting increased interest from researchers and practitioners in basic science, pre-clinical and clinical arenas. A combination of better labeling reagents and better optics creates opportunities to detect and measure multiple parameters at the molecular and cellular level. These tools can provide valuable insights into the basic mechanisms of life, and yield diagnostic and prognostic information for clinical applications. There are many multispectral technologies available, each with its own advantages and limitations. This chapter will present an overview of the rationale for spectral imaging, and discuss the hardware, software and sample labeling strategies that can optimize its usefulness in clinical settings

A digital microarray using interferometric detection of plasmonic nanorod labels

DNA and protein microarrays are a high-throughput technology that allow the simultaneous quantification of tens of thousands of different biomolecular species. The mediocre sensitivity and dynamic range of traditional fluorescence microarrays compared to other techniques have been the technology's Achilles' Heel, and prevented their adoption for many biomedical and clinical diagnostic applications. Previous work to enhance the sensitivity of microarray readout to the single-molecule ('digital') regime have either required signal amplifying chemistry or sacrificed throughput, nixing the platform's primary advantages. Here, we report the development of a digital microarray which extends both the sensitivity and dynamic range of microarrays by about three orders of magnitude. This technique uses functionalized gold nanorods as single-molecule labels and an interferometric scanner which can rapidly enumerate individual nanorods by imaging them with a 10x objective lens. This approach does not require any chemical enhancement such as silver deposition, and scans arrays with a throughput similar to commercial fluorescence devices. By combining single-nanoparticle enumeration and ensemble measurements of spots when the particles are very dense, this system achieves a dynamic range of about one million directly from a single scan