Quality-based Multimodal Classification Using Tree-Structured Sparsity

Recent studies have demonstrated advantages of information fusion based on sparsity models for multimodal classification. Among several sparsity models, tree-structured sparsity provides a flexible framework for extraction of cross-correlated information from different sources and for enforcing group sparsity at multiple granularities. However, the existing algorithm only solves an approximated version of the cost functional and the resulting solution is not necessarily sparse at group levels. This paper reformulates the tree-structured sparse model for multimodal classification task. An accelerated proximal algorithm is proposed to solve the optimization problem, which is an efficient tool for feature-level fusion among either homogeneous or heterogeneous sources of information. In addition, a (fuzzy-set-theoretic) possibilistic scheme is proposed to weight the available modalities, based on their respective reliability, in a joint optimization problem for finding the sparsity codes. This approach provides a general framework for quality-based fusion that offers added robustness to several sparsity-based multimodal classification algorithms. To demonstrate their efficacy, the proposed methods are evaluated on three different applications - multiview face recognition, multimodal face recognition, and target classification.Comment: To Appear in 2014 IEEE Conference on Computer Vision and Pattern Recognition (CVPR 2014

Multi-view Fuzzy Representation Learning with Rules based Model

Unsupervised multi-view representation learning has been extensively studied for mining multi-view data. However, some critical challenges remain. On the one hand, the existing methods cannot explore multi-view data comprehensively since they usually learn a common representation between views, given that multi-view data contains both the common information between views and the specific information within each view. On the other hand, to mine the nonlinear relationship between data, kernel or neural network methods are commonly used for multi-view representation learning. However, these methods are lacking in interpretability. To this end, this paper proposes a new multi-view fuzzy representation learning method based on the interpretable Takagi-Sugeno-Kang (TSK) fuzzy system (MVRL_FS). The method realizes multi-view representation learning from two aspects. First, multi-view data are transformed into a high-dimensional fuzzy feature space, while the common information between views and specific information of each view are explored simultaneously. Second, a new regularization method based on L_(2,1)-norm regression is proposed to mine the consistency information between views, while the geometric structure of the data is preserved through the Laplacian graph. Finally, extensive experiments on many benchmark multi-view datasets are conducted to validate the superiority of the proposed method.Comment: This work has been accepted by IEEE Transactions on Knowledge and Data Engineerin

Machine Learning and Integrative Analysis of Biomedical Big Data.

Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues