1,882 research outputs found

    Nutrition and Rheumatoid Arthritis in the ‘Omics’ Era

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    Modern high-throughput ‘omics’ science tools (including genomics, transcriptomics, pro teomics, metabolomics and microbiomics) are currently being applied to nutritional sciences to unravel the fundamental processes of health effects ascribed to particular nutrients in humans and to contribute to more precise nutritional advice. Diet and food components are key environmental factors that interact with the genome, transcriptome, proteome, metabolome and the microbiota, and this life-long interplay defines health and diseases state of the individual. Rheumatoid arthritis (RA) is a chronic autoimmune disease featured by a systemic immune-inflammatory response, in genetically susceptible individuals exposed to environmental triggers, including diet. In recent years increasing evidences suggested that nutritional factors and gut microbiome have a central role in RA risk and progression. The aim of this review is to summarize the main and most recent applications of ‘omics’ technologies in human nutrition and in RA research, examining the possible influences of some nutrients and nutritional patterns on RA pathogenesis, following a nutrigenomics approach. The opportunities and challenges of novel ‘omics technologies’ in the exploration of new avenues in RA and nutritional research to prevent and manage RA will be also discussed

    National Aboriginal and Torres Strait Islander health plan 2013-2023

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    In 2008 Australian Governments committed to work with Aboriginal and Torres Strait Islander people on an incredibly important task - to achieve equality in health status and life expectancy between Aboriginal and Torres Strait Islander people and non-Indigenous Australians by the year 2031. The commitment – in the form of the Close the Gap Statement of Intent – creates the platform for this National Aboriginal and Torres Strait Islander Health Plan, which has been developed in partnership with Aboriginal and Torres Strait Islander people and their representatives. This Health Plan provides a long-term, evidence-based policy framework as part of the overarching Council of Australian Governments’ (COAG) approach to Closing the Gap in Indigenous disadvantage, which has been set out in the National Indigenous Reform Agreement (NIRA) signed in 2008. The NIRA has established a framework of national targets and policy building blocks. Two of the Closing the Gap targets, to halve the gap in child mortality by 2018 and close the life expectancy gap by 2031, go directly to health outcomes, while others address social determinants of health such as education and employment. The Health Plan builds on the United Nations Declaration on the Rights of Indigenous Peoples. It adopts a strengths-based approach to ensure policies and programs improve health, social and emotional wellbeing, and resilience and promote positive health behaviours. It emphasises the centrality of culture in the health of Aboriginal and Torres Strait Islander people and the rights of individuals to a safe, healthy and empowered life. The Health Plan also builds on existing strategies and planning approaches to improving Aboriginal and Torres Strait Islander health,

    Design for Multi-Dimensional Stages of Lymphoedema Self-Management

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    This study investigates the experience of people with the chronic medical condition lymphoedema, to inform the design of new products. Articles from literature that describe lived lymphoedema experiences are thematically synthesised from a behavioural lens. People with lymphoedema go through stages toward achieving levels of expertise, motivation and routine, to maintain effective self-management in the long-term. A preliminary framework is proposed that presents four themes (competence, autonomy, daily routine and socio-psychological) and their stages. The purpose of the framework is to assist designers in understanding how people with lymphoedema experience self-management. Focusing on facilitating a transition through these multi-dimensional stages is suggested as a means to aid the design of supportive health products. Related design implementations are discussed through product examples. This framework is developed as part of a wider research project, where the following stages will be concerned with refinement of the framework through primary research with people with lymphoedema and their healthcare providers

    Leveling the Playing Field: Attracting, Engaging, and Advancing People with Disabilities

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    People with disabilities experience significant challenges in finding employment. The participation of people with disabilities in the workforce and their median income are both less than half that of the civilian workforce. They work part time 68 percent more frequently than people without disabilities. These disheartening results persist despite the enactment of significant federal legislation aimed at making the workplace more supportive and accessible to people with disabilities. The Conference Board Research Working Group (RWG) on Improving Employment Outcomes for People with Disabilities was convened to address how to overcome these disparities. It was sponsored by the Employment and Disability Institute at Cornell University, under a grant from the National Institute on Disability and Rehabilitation Research of the U.S. Department of Education. The RWG members focused on four questions: 1) The business case: Is it advantageous for organizations to employ people with disabilities? 2) Organizational readiness: What should organizations do to create a workplace that enables people with disabilities to thrive and advance? 3) Measurement: How can success for both people with disabilities and the organization itself be determined? 4) Self-disclosure: How can people with disabilities, especially those whose disabilities are not obvious, be encouraged to identify themselves so that resources can be directed toward them and outcomes can be measured

    Online ISBN: 978-1-74241-980-0 Publications approval number: 10290

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    work in unaltered form for your own personal use or, if you are part of an organisation, for internal use within your organisation, but only if you or your organisation do not use the reproduction for any commercial purpose and retain this copyright notice and all disclaimer notices as part of that reproduction. Apart from rights to use as permitted by the Copyright Act 1968 or allowed by this copyright notice, all other rights are reserved and you are not allowed to reproduce the whole or any part of this work in any way (electronic or otherwise) without first being given the specific written permission from the Commonwealth to do so. Requests and inquiries concerning reproduction and rights are to be sent to the Online, Service

    Knowledge of Assistive Technology and Services Available to Students With Disabilities

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    The purpose of this study was to investigate the knowledge of students and faculty regarding the assistive technology and services available to students with disabilities at a university in the southeastern United States. This study consists of 300 participants who were asked to respond to 8 questions which were designed to collect data aligned with the three research objectives. The findings may be used to determine if further education or communication is needed in order to better inform students, staff, and faculty of assistive technology and services available on campus
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