13,977 research outputs found
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Ensuring Access to Safe and Nutritious Food for All Through the Transformation of Food Systems
Die akute Appendizitis im Kindes- und Jugendalter: neue diagnostische Verfahren für die prätherapeutische Differenzierung histopathologischer Entitäten zur Unterstützung konservativer Therapiestrategien
Hintergrund der hier zusammengefassten Studien war die aktuelle Datenlage, die dafür spricht, dass es sich bei der klinisch unkomplizierten, histopathologisch phlegmonösen und der klinisch komplizierten, histopathologisch gangränösen Appendizitis um unabhängige Entitäten handelt. Diese können unterschiedlichen Therapieoptionen (konservativ vs. operativ) zugeführt werden. Vor diesem Hintergrund war es ein Ziel der Arbeiten zu untersuchen, wie die Formen der akuten Appendizitis im Kindes- und Jugendalter bereits prätherapeutisch unterschieden werden können.
Sowohl in der Labordiagnostik (P1 und P2) als auch im Ultraschall (P3) lassen sich Unterschiede zwischen Patient*innen mit unkomplizierter, phlegmonöser und komplizierter (gangränöser und perforierender) Appendizitis aufzeigen. Hierdurch allein kann allerdings aufgrund unzureichender Trennschärfe noch keine ausreichende Entscheidungssicherheit erreicht werden. Mit Verfahren der künstlichen Intelligenz auf Untersucher-unabhängige diagnostische Parameter (P4) konnte die Vorhersagegenauigkeit der akuten Appendizitis weiter gesteigert werden. Interessante Ergebnisse bezüglich der unterschiedlichen Pathomechanismen der beiden inflammatorischen Entitäten ergaben sich durch eine differenzielle Genexpressionsanalyse (P5). In einer Proof-of-Concept-Studie wurden zuvor beschriebene Methoden der künstlichen Intelligenz auf die Genexpressionsdaten angewandt (P6). Hierdurch konnte im Modell eine grundsätzliche Differenzierbarkeit der Entitäten durch die Anwendung der neuen Methode aufgezeigt werden.
Ein mittelfristiges Ziel ist es, eine Biomarkersignatur zu definieren, die ihre Aussagekraft durch einen Computeralgorithmus hat. Hierdurch soll eine schnelle Therapieentscheidung ermöglicht werden. Im Idealfall sollte diese Biomarkersignatur sicher, objektiv und einfach zu bestimmen sein sowie eine höhere diagnostische Sicherheit als die bisherige Diagnostik mittels Anamnese, Untersuchung, Laboranalyse und Ultraschall bieten.
Langfristiges Ziel von Folgestudien ist die Identifizierung einer Biomarkersignatur mit der bestmöglichen Vorhersagekraft. Hinsichtlich der routinemäßigen klinischen Diagnostik ist die Anwendung von Point-of-Care Devices auf PCR-Basis denkbar. Hier könnte eine limitierte Anzahl von Primern für eine Biomarkersignatur mit hoher Vorhersagekraft zum Einsatz kommen. Der dadurch ermittelte Biomarker würde seine Aussagekraft durch einen einfach anzuwendenden Computeralgorithmus erhalten. Die Kombination aus Genexpressionsanalyse mit Methoden der künstlichen Intelligenz kann somit die Grundlage für ein neues diagnostisches Instrument zur sicheren Unterscheidung unterschiedlicher Appendizitisentitäten darstellen
latent Dirichlet allocation method-based nowcasting approach for prediction of silver price
Silver is a metal that offers significant value to both investors and companies. The purpose of this study is to make an estimation of the price of silver. While making this estimation, it is planned to include the frequency of searches on Google Trends for the words that affect the silver price. Thus, it is aimed to obtain a more accurate estimate. First, using the Latent Dirichlet Allocation method, the keywords to be analyzed in Google Trends were collected from various articles on the Internet. Mining data from Google Trends combined with the information obtained by LDA is the new approach this study took, to predict the price of silver. No study has been found in the literature that has adopted this approach to estimate the price of silver. The estimation was carried out with Random Forest Regression, Gaussian Process Regression, Support Vector Machine, Regression Trees and Artificial Neural Networks methods. In addition, ARIMA, which is one of the traditional methods that is widely used in time series analysis, was also used to benchmark the accuracy of the methodology. The best MSE ratio was obtained as 0,000227131 ± 0.0000235205 by the Regression Trees method. This score indicates that it would be a valid technique to estimate the price of "Silver" by using Google Trends data using the LDA method
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Antecedents of business intelligence system use
This thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University London.Organisational reliance on information has become vital for organisational competitiveness. With increasing data volumes, Business Intelligence (BI) becomes a cornerstone of the decision-support system. However, employee resistance to use Business Intelligence Systems (BIS) is evident. This creates a problem to organisations in realising the benefits of BIS. It is thus important to study the enablers of sustained use of BIS amongst employees.
This thesis identifies existing theories that can be used to study BI system use. It integrates and extends technology use theories through a framework focusing on Business Intelligence System Use (BISU). Empirical research is then conducted in Kuwait’s telecom and banking industries through a close-ended, self-administered questionnaire using a five-point Likert scale. Responses were received from 211 BI users. The data was analysed using SmartPLS to study the convergent and discriminant validity and reliability. Partial least squares structural equation modelling (PLS-SEM) was used to study the direct and indirect relationships between constructs and answer the hypotheses. In addition to SmartPLS, SPSS was used for descriptive analysis.
The results indicated that UTAUT factors consisting of performance expectancy, effort expectancy and social influence positively impact BI system use. Voluntariness of use was found to positively moderate the relationship between social influence and BI system use. Furthermore, BI system quality positively impacts both performance expectancy and effort expectancy. The BI user’s self-efficacy also positively impacts effort expectancy. In addition, social influence was found to be positively influenced by organisational factors, namely top management support and information culture.
The findings of this research contribute to literature by determining and quantifying the factors that influence BISU through the lens of employee perspectives. This thesis also explains how employees’ object-based beliefs about BI affect their behavioural beliefs, which in turn impact BISU. Limitations of this research include the omission of UTAUT’s facilitating conditions and the limited variance of respondent demographics
Annals [...].
Pedometrics: innovation in tropics; Legacy data: how turn it useful?; Advances in soil sensing; Pedometric guidelines to systematic soil surveys.Evento online. Coordenado por: Waldir de Carvalho Junior, Helena Saraiva Koenow Pinheiro, Ricardo SimĂŁo Diniz Dalmolin
Compatibility and challenges in machine learning approach for structural crack assessment
Structural health monitoring and assessment (SHMA) is exceptionally essential for preserving and sustaining any mechanical structure’s service life. A successful assessment should provide reliable and resolute information to maintain the continuous performance of the structure. This information can effectively determine crack progression and its overall impact on the structural operation. However, the available sensing techniques and methods for performing SHMA generate raw measurements that require significant data processing before making any valuable predictions. Machine learning (ML) algorithms (supervised and unsupervised learning) have been extensively used for such data processing. These algorithms extract damage-sensitive features from the raw data to identify structural conditions and performance. As per the available published literature, the extraction of these features has been quite random and used by academic researchers without a suitability justification. In this paper, a comprehensive literature review is performed to emphasise the influence of damage-sensitive features on ML algorithms. The selection and suitability of these features are critically reviewed while processing raw data obtained from different materials (metals, composites and polymers). It has been found that an accurate crack prediction is only possible if the selection of damage-sensitive features and ML algorithms is performed based on available raw data and structure material type. This paper also highlights the current challenges and limitations during the mentioned sections
Growth trends and site productivity in boreal forests under management and environmental change: insights from long-term surveys and experiments in Sweden
Under a changing climate, current tree and stand growth information is indispensable to the carbon sink strength of boreal forests. Important questions regarding tree growth are to what extent have management and environmental change influenced it, and how it might respond in the future. In this thesis, results from five studies (Papers I-V) covering growth trends, site productivity, heterogeneity in managed forests and potentials for carbon storage in forests and harvested wood products via differing management strategies are presented. The studies were based on observations from national forest inventories and long-term experiments in Sweden. The annual height growth of Scots pine (Pinus sylvestris) and Norway spruce (Picea abies) had increased, especially after the millennium shift, while the basal area growth remains stable during the last 40 years (Papers I-II). A positive response on height growth with increasing temperature was observed. The results generally imply a changing growing condition and stand composition. In Paper III, yield capacity of conifers was analysed and compared with existing functions. The results showed that there is a bias in site productivity estimates and the new functions give better prediction of the yield capacity in Sweden. In Paper IV, the variability in stand composition was modelled as indices of heterogeneity to calibrate the relationship between basal area and leaf area index in managed stands of Norway spruce and Scots pine. The results obtained show that the stand structural heterogeneity effects here are of such a magnitude that they cannot be neglected in the implementation of hybrid growth models, especially those based on light interception and light-use efficiency. In the long-term, the net climate benefits in Swedish forests may be maximized through active forest management with high harvest levels and efficient product utilization, compared to increasing carbon storage in standing forests through land set-asides for nature conservation (Paper V). In conclusion, this thesis offers support for the development of evidence-based policy recommendations for site-adapted and sustainable management of Swedish forests in a changing climate
The Adirondack Chronology
The Adirondack Chronology is intended to be a useful resource for researchers and others interested in the Adirondacks and Adirondack history.https://digitalworks.union.edu/arlpublications/1000/thumbnail.jp
Full stack development toward a trapped ion logical qubit
Quantum error correction is a key step toward the construction of a large-scale quantum computer, by preventing small infidelities in quantum gates from accumulating over the course of an algorithm. Detecting and correcting errors is achieved by using multiple physical qubits to form a smaller number of robust logical
qubits. The physical implementation of a logical qubit requires multiple qubits, on which high fidelity gates
can be performed.
The project aims to realize a logical qubit based on ions confined on a microfabricated surface trap. Each
physical qubit will be a microwave dressed state qubit based on 171Yb+ ions. Gates are intended to be realized through RF and microwave radiation in combination with magnetic field gradients. The project vertically integrates software down to hardware compilation layers in order to deliver, in the near future, a fully functional small device demonstrator.
This thesis presents novel results on multiple layers of a full stack quantum computer model. On the hardware level a robust quantum gate is studied and ion displacement over the X-junction geometry is demonstrated.
The experimental organization is optimized through automation and compressed waveform data transmission. A new quantum assembly language purely dedicated to trapped ion quantum computers is introduced. The demonstrator is aimed at testing implementation of quantum error correction codes while preparing for larger
scale iterations.Open Acces
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