48,085 research outputs found

    Cloud Computing for Next-Generation Sequencing Data Analysis

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    High-throughput next-generation sequencing (NGS) technologies have evolved rapidly and are reshaping the scope of genomics research. The substantial decrease in the cost of NGS techniques in the past decade has led to its rapid adoption in biological research and drug development. Genomics studies of large populations are producing a huge amount of data, giving rise to computational issues around the storage, transfer, and analysis of the data. Fortunately, cloud computing has recently emerged as a viable option to quickly and easily acquire the computational resources for large-scale NGS data analyses. Some cloud-based applications and resources have been developed specifically to address the computational challenges of working with very large volumes of data generated by NGS technology. In this chapter, we will review some cloud-based systems and solutions for NGS data analysis, discuss the practical hurdles and limitations in cloud computing, including data transfer and security, and share the lessons we learned from the implementation of Rainbow, a cloud-based tool for large-scale genome sequencing data analysis

    ARTIST: Model-Based Stairway to the Cloud

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    International audienceOver the past decade, cloud services emerged as one of the most promising technologies in IT. Since cloud computing allows improving the quality of software and, at the same time, aims at reducing costs of operating software and hardware, more and more software is delivered as a service in the cloud. However , moving existing software applications to the cloud and making them behave as software as a service is still a major challenge. In fact, in addition to technical aspects, business aspects also need to be considered. The ARTIST EU project (FP7) proposes a comprehensive model-based modernization approach, covering both business and technical aspects, to cloudify already existing software. In particular , ARTIST employs MDE techniques to automate the reverse engineering and forward engineering phases in a way that modernized software truly benefits from targeted cloud environments. In this paper we describe the overall ARTIST approach and present several lessons learned

    Alma in the Cloud: Implementation Through the Eyes of Acquisitions

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    For the past few years, cloud computing has taken wing, and libraries are embracing this technology. The Virginia Commonwealth University (VCU) Libraries is one of the libraries that is embracing the cloud by implementing Alma, a cloud-based library management system. This article will provide an overview of the VCU Libraries’s journey from implementation up until “Go Live” through the eyes of the Acquisitions Department. The VCU Libraries was on the verge of buying two new servers to support its operations. After researching available library management systems, Alma was found to be an attractive prospect. Around the same time, the Libraries was looking for a discovery tool, Primo, and felt that Primo and Alma, both Ex Libris products, would be a good fit. After showing a true interest in Alma, VCU received an invitation to upgrade its software as an “early adopter” that was being offered to only 12 North American libraries in 2011. As early adopters, there were many challenges encountered by the Implementation Task Force. The Task Force had to make configuration decisions, attend training sessions, conduct internal training sessions, analyze existing workflows, and review configuration and migrated data. This article will document the Libraries’s journey in the cloud. A discussion of opportunities and challenges are discussed. Readers will learn about processes, cleanup and workflow issues and timetables. Finally, this article will share some lessons learned by different members of the Alma Implementation Task Force

    On Evaluating Commercial Cloud Services: A Systematic Review

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    Background: Cloud Computing is increasingly booming in industry with many competing providers and services. Accordingly, evaluation of commercial Cloud services is necessary. However, the existing evaluation studies are relatively chaotic. There exists tremendous confusion and gap between practices and theory about Cloud services evaluation. Aim: To facilitate relieving the aforementioned chaos, this work aims to synthesize the existing evaluation implementations to outline the state-of-the-practice and also identify research opportunities in Cloud services evaluation. Method: Based on a conceptual evaluation model comprising six steps, the Systematic Literature Review (SLR) method was employed to collect relevant evidence to investigate the Cloud services evaluation step by step. Results: This SLR identified 82 relevant evaluation studies. The overall data collected from these studies essentially represent the current practical landscape of implementing Cloud services evaluation, and in turn can be reused to facilitate future evaluation work. Conclusions: Evaluation of commercial Cloud services has become a world-wide research topic. Some of the findings of this SLR identify several research gaps in the area of Cloud services evaluation (e.g., the Elasticity and Security evaluation of commercial Cloud services could be a long-term challenge), while some other findings suggest the trend of applying commercial Cloud services (e.g., compared with PaaS, IaaS seems more suitable for customers and is particularly important in industry). This SLR study itself also confirms some previous experiences and reveals new Evidence-Based Software Engineering (EBSE) lessons

    TLAD 2011 Proceedings:9th international workshop on teaching, learning and assesment of databases (TLAD)

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    This is the ninth in the series of highly successful international workshops on the Teaching, Learning and Assessment of Databases (TLAD 2011), which once again is held as a workshop of BNCOD 2011 - the 28th British National Conference on Databases. TLAD 2011 is held on the 11th July at Manchester University, just before BNCOD, and hopes to be just as successful as its predecessors.The teaching of databases is central to all Computing Science, Software Engineering, Information Systems and Information Technology courses, and this year, the workshop aims to continue the tradition of bringing together both database teachers and researchers, in order to share good learning, teaching and assessment practice and experience, and further the growing community amongst database academics. As well as attracting academics from the UK community, the workshop has also been successful in attracting academics from the wider international community, through serving on the programme committee, and attending and presenting papers.Due to the healthy number of high quality submissions this year, the workshop will present eight peer reviewed papers. Of these, six will be presented as full papers and two as short papers. These papers cover a number of themes, including: the teaching of data mining and data warehousing, databases and the cloud, and novel uses of technology in teaching and assessment. It is expected that these papers will stimulate discussion at the workshop itself and beyond. This year, the focus on providing a forum for discussion is enhanced through a panel discussion on assessment in database modules, with David Nelson (of the University of Sunderland), Al Monger (of Southampton Solent University) and Charles Boisvert (of Sheffield Hallam University) as the expert panel
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