Medical imaging analysis with artificial neural networks

Given that neural networks have been widely reported in the research community of medical imaging, we provide a focused literature survey on recent neural network developments in computer-aided diagnosis, medical image segmentation and edge detection towards visual content analysis, and medical image registration for its pre-processing and post-processing, with the aims of increasing awareness of how neural networks can be applied to these areas and to provide a foundation for further research and practical development. Representative techniques and algorithms are explained in detail to provide inspiring examples illustrating: (i) how a known neural network with fixed structure and training procedure could be applied to resolve a medical imaging problem; (ii) how medical images could be analysed, processed, and characterised by neural networks; and (iii) how neural networks could be expanded further to resolve problems relevant to medical imaging. In the concluding section, a highlight of comparisons among many neural network applications is included to provide a global view on computational intelligence with neural networks in medical imaging

Brain-inspired self-organization with cellular neuromorphic computing for multimodal unsupervised learning

Cortical plasticity is one of the main features that enable our ability to learn and adapt in our environment. Indeed, the cerebral cortex self-organizes itself through structural and synaptic plasticity mechanisms that are very likely at the basis of an extremely interesting characteristic of the human brain development: the multimodal association. In spite of the diversity of the sensory modalities, like sight, sound and touch, the brain arrives at the same concepts (convergence). Moreover, biological observations show that one modality can activate the internal representation of another modality when both are correlated (divergence). In this work, we propose the Reentrant Self-Organizing Map (ReSOM), a brain-inspired neural system based on the reentry theory using Self-Organizing Maps and Hebbian-like learning. We propose and compare different computational methods for unsupervised learning and inference, then quantify the gain of the ReSOM in a multimodal classification task. The divergence mechanism is used to label one modality based on the other, while the convergence mechanism is used to improve the overall accuracy of the system. We perform our experiments on a constructed written/spoken digits database and a DVS/EMG hand gestures database. The proposed model is implemented on a cellular neuromorphic architecture that enables distributed computing with local connectivity. We show the gain of the so-called hardware plasticity induced by the ReSOM, where the system's topology is not fixed by the user but learned along the system's experience through self-organization.Comment: Preprin

A Study Of Factors Contributing To Self-reported Anomalies In Civil Aviation

A study investigating what factors are present leading to pilots submitting voluntary anomaly reports regarding their flight performance was conducted. The study employed statistical methods, text mining, clustering, and dimensional reduction techniques in an effort to determine relationships between factors and anomalies. A review of the literature was conducted to determine what factors are contributing to these anomalous incidents, as well as what research exists on human error, its causes, and its management. Data from the NASA Aviation Safety Reporting System (ASRS) was analyzed using traditional statistical methods such as frequencies and multinomial logistic regression. Recently formalized approaches in text mining such as Knowledge Based Discovery (KBD) and Literature Based Discovery (LBD) were employed to create associations between factors and anomalies. These methods were also used to generate predictive models. Finally, advances in dimensional reduction techniques identified concepts or keywords within records, thus creating a framework for an unsupervised document classification system. Findings from this study reinforced established views on contributing factors to civil aviation anomalies. New associations between previously unrelated factors and conditions were also found. Dimensionality reduction also demonstrated the possibility of identifying salient factors from unstructured text records, and was able to classify these records using these identified features

Unsupervised Heart-rate Estimation in Wearables With Liquid States and A Probabilistic Readout

Heart-rate estimation is a fundamental feature of modern wearable devices. In this paper we propose a machine intelligent approach for heart-rate estimation from electrocardiogram (ECG) data collected using wearable devices. The novelty of our approach lies in (1) encoding spatio-temporal properties of ECG signals directly into spike train and using this to excite recurrently connected spiking neurons in a Liquid State Machine computation model; (2) a novel learning algorithm; and (3) an intelligently designed unsupervised readout based on Fuzzy c-Means clustering of spike responses from a subset of neurons (Liquid states), selected using particle swarm optimization. Our approach differs from existing works by learning directly from ECG signals (allowing personalization), without requiring costly data annotations. Additionally, our approach can be easily implemented on state-of-the-art spiking-based neuromorphic systems, offering high accuracy, yet significantly low energy footprint, leading to an extended battery life of wearable devices. We validated our approach with CARLsim, a GPU accelerated spiking neural network simulator modeling Izhikevich spiking neurons with Spike Timing Dependent Plasticity (STDP) and homeostatic scaling. A range of subjects are considered from in-house clinical trials and public ECG databases. Results show high accuracy and low energy footprint in heart-rate estimation across subjects with and without cardiac irregularities, signifying the strong potential of this approach to be integrated in future wearable devices.Comment: 51 pages, 12 figures, 6 tables, 95 references. Under submission at Elsevier Neural Network