On Interpretability of Deep Learning based Skin Lesion Classifiers using Concept Activation Vectors

Deep learning based medical image classifiers have shown remarkable prowess in various application areas like ophthalmology, dermatology, pathology, and radiology. However, the acceptance of these Computer-Aided Diagnosis (CAD) systems in real clinical setups is severely limited primarily because their decision-making process remains largely obscure. This work aims at elucidating a deep learning based medical image classifier by verifying that the model learns and utilizes similar disease-related concepts as described and employed by dermatologists. We used a well-trained and high performing neural network developed by REasoning for COmplex Data (RECOD) Lab for classification of three skin tumours, i.e. Melanocytic Naevi, Melanoma and Seborrheic Keratosis and performed a detailed analysis on its latent space. Two well established and publicly available skin disease datasets, PH2 and derm7pt, are used for experimentation. Human understandable concepts are mapped to RECOD image classification model with the help of Concept Activation Vectors (CAVs), introducing a novel training and significance testing paradigm for CAVs. Our results on an independent evaluation set clearly shows that the classifier learns and encodes human understandable concepts in its latent representation. Additionally, TCAV scores (Testing with CAVs) suggest that the neural network indeed makes use of disease-related concepts in the correct way when making predictions. We anticipate that this work can not only increase confidence of medical practitioners on CAD but also serve as a stepping stone for further development of CAV-based neural network interpretation methods.Comment: Accepted for the IEEE International Joint Conference on Neural Networks (IJCNN) 202

Visual Entailment: A Novel Task for Fine-Grained Image Understanding

Existing visual reasoning datasets such as Visual Question Answering (VQA), often suffer from biases conditioned on the question, image or answer distributions. The recently proposed CLEVR dataset addresses these limitations and requires fine-grained reasoning but the dataset is synthetic and consists of similar objects and sentence structures across the dataset. In this paper, we introduce a new inference task, Visual Entailment (VE) - consisting of image-sentence pairs whereby a premise is defined by an image, rather than a natural language sentence as in traditional Textual Entailment tasks. The goal of a trained VE model is to predict whether the image semantically entails the text. To realize this task, we build a dataset SNLI-VE based on the Stanford Natural Language Inference corpus and Flickr30k dataset. We evaluate various existing VQA baselines and build a model called Explainable Visual Entailment (EVE) system to address the VE task. EVE achieves up to 71% accuracy and outperforms several other state-of-the-art VQA based models. Finally, we demonstrate the explainability of EVE through cross-modal attention visualizations. The SNLI-VE dataset is publicly available at https://github.com/ necla-ml/SNLI-VE

Explanation Techniques using Markov Logic Networks

Explanation Techniques using Markov Logic Network