142 research outputs found

    Breast cancer diagnosis: a survey of pre-processing, segmentation, feature extraction and classification

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    Machine learning methods have been an interesting method in the field of medical for many years, and they have achieved successful results in various fields of medical science. This paper examines the effects of using machine learning algorithms in the diagnosis and classification of breast cancer from mammography imaging data. Cancer diagnosis is the identification of images as cancer or non-cancer, and this involves image preprocessing, feature extraction, classification, and performance analysis. This article studied 93 different references mentioned in the previous years in the field of processing and tries to find an effective way to diagnose and classify breast cancer. Based on the results of this research, it can be concluded that most of today’s successful methods focus on the use of deep learning methods. Finding a new method requires an overview of existing methods in the field of deep learning methods in order to make a comparison and case study

    Breast Density Estimation and Micro-Calcification Classification

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    Modular Machine Learning Methods for Computer-Aided Diagnosis of Breast Cancer

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    The purpose of this study was to improve breast cancer diagnosis by reducing the number of benign biopsies performed. To this end, we investigated modular and ensemble systems of machine learning methods for computer-aided diagnosis (CAD) of breast cancer. A modular system partitions the input space into smaller domains, each of which is handled by a local model. An ensemble system uses multiple models for the same cases and combines the models\u27 predictions. Five supervised machine learning techniques (LDA, SVM, BP-ANN, CBR, CART) were trained to predict the biopsy outcome from mammographic findings (BIRADS™) and patient age based on a database of 2258 cases mixed from multiple institutions. The generalization of the models was tested on second set of 2177 cases. Clusters were identified in the database using a priori knowledge and unsupervised learning methods (agglomerative hierarchical clustering followed by K-Means, SOM, AutoClass). The performance of the global models over the clusters was examined and local models were trained for clusters. While some local models were superior to some global models, we were unable to build a modular CAD system that was better than the global BP-ANN model. The ensemble systems based on simplistic combination schemes did not result in significant improvements and more complicated combination schemes were found to be unduly optimistic. One of the most striking results of this dissertation was that CAD systems trained on a mixture of lesion types performed much better on masses than on calcifications. Our study of the institutional effects suggests that models built on cases mixed between institutions may overcome some of the weaknesses of models built on cases from a single institution. It was suggestive that each of the unsupervised methods identified a cluster of younger women with well-circumscribed or obscured, oval-shaped masses that accounted for the majority of the BP-ANN’s recommendations for follow up. From the cluster analysis and the CART models, we determined a simple diagnostic rule that performed comparably to the global BP-ANN. Approximately 98% sensitivity could be maintained while providing approximately 26% specificity. This should be compared to the clinical status quo of 100% sensitivity and 0% specificity on this database of indeterminate cases already referred to biopsy
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