Mammalian Brain As a Network of Networks

Acknowledgements AZ, SG and AL acknowledge support from the Russian Science Foundation (16-12-00077). Authors thank T. Kuznetsova for Fig. 6.Peer reviewedPublisher PD

Dynamics of Oscillators Coupled by a Medium with Adaptive Impact

In this article we study the dynamics of coupled oscillators. We use mechanical metronomes that are placed over a rigid base. The base moves by a motor in a one-dimensional direction and the movements of the base follow some functions of the phases of the metronomes (in other words, it is controlled to move according to a provided function). Because of the motor and the feedback, the phases of the metronomes affect the movements of the base while on the other hand, when the base moves, it affects the phases of the metronomes in return. For a simple function for the base movement (such as $y = \gamma_{x} [r \theta_1 + (1 - r) \theta_2]$ in which $y$ is the velocity of the base, $\gamma_{x}$ is a multiplier, $r$ is a proportion and $\theta_1$ and $\theta_2$ are phases of the metronomes), we show the effects on the dynamics of the oscillators. Then we study how this function changes in time when its parameters adapt by a feedback. By numerical simulations and experimental tests, we show that the dynamic of the set of oscillators and the base tends to evolve towards a certain region. This region is close to a transition in dynamics of the oscillators; where more frequencies start to appear in the frequency spectra of the phases of the metronomes

The Kinetic Basis of Self-Organized Pattern Formation

In his seminal paper on morphogenesis (1952), Alan Turing demonstrated that different spatio-temporal patterns can arise due to instability of the homogeneous state in reaction-diffusion systems, but at least two species are necessary to produce even the simplest stationary patterns. This paper is aimed to propose a novel model of the analog (continuous state) kinetic automaton and to show that stationary and dynamic patterns can arise in one-component networks of kinetic automata. Possible applicability of kinetic networks to modeling of real-world phenomena is also discussed.Comment: 8 pages, submitted to the 14th International Conference on the Synthesis and Simulation of Living Systems (Alife 14) on 23.03.2014, accepted 09.05.201

A Review on Biological Inspired Computation in Cryptology

Cryptology is a field that concerned with cryptography and cryptanalysis. Cryptography, which is a key technology in providing a secure transmission of information, is a study of designing strong cryptographic algorithms, while cryptanalysis is a study of breaking the cipher. Recently biological approaches provide inspiration in solving problems from various fields. This paper reviews major works in the application of biological inspired computational (BIC) paradigm in cryptology. The paper focuses on three BIC approaches, namely, genetic algorithm (GA), artificial neural network (ANN) and artificial immune system (AIS). The findings show that the research on applications of biological approaches in cryptology is minimal as compared to other fields. To date only ANN and GA have been used in cryptanalysis and design of cryptographic primitives and protocols. Based on similarities that AIS has with ANN and GA, this paper provides insights for potential application of AIS in cryptology for further research

Theory of Robustness of Irreversible Differentiation in a Stem Cell System: Chaos hypothesis

Based on extensive study of a dynamical systems model of the development of a cell society, a novel theory for stem cell differentiation and its regulation is proposed as the ``chaos hypothesis''. Two fundamental features of stem cell systems - stochastic differentiation of stem cells and the robustness of a system due to regulation of this differentiation - are found to be general properties of a system of interacting cells exhibiting chaotic intra-cellular reaction dynamics and cell division, whose presence does not depend on the detail of the model. It is found that stem cells differentiate into other cell types stochastically due to a dynamical instability caused by cell-cell interactions, in a manner described by the Isologous Diversification theory. This developmental process is shown to be stable not only with respect to molecular fluctuations but also with respect to removal of cells. With this developmental process, the irreversible loss of multipotency accompanying the change from a stem cell to a differentiated cell is shown to be characterized by a decrease in the chemical diversity in the cell and of the complexity of the cellular dynamics. The relationship between the division speed and this loss of multipotency is also discussed. Using our model, some predictions that can be tested experimentally are made for a stem cell system.Comment: 31 pages, 10 figures, submitted to Jour. Theor. Bio

Evolutionary Neural Gas (ENG): A Model of Self Organizing Network from Input Categorization

Despite their claimed biological plausibility, most self organizing networks have strict topological constraints and consequently they cannot take into account a wide range of external stimuli. Furthermore their evolution is conditioned by deterministic laws which often are not correlated with the structural parameters and the global status of the network, as it should happen in a real biological system. In nature the environmental inputs are noise affected and fuzzy. Which thing sets the problem to investigate the possibility of emergent behaviour in a not strictly constrained net and subjected to different inputs. It is here presented a new model of Evolutionary Neural Gas (ENG) with any topological constraints, trained by probabilistic laws depending on the local distortion errors and the network dimension. The network is considered as a population of nodes that coexist in an ecosystem sharing local and global resources. Those particular features allow the network to quickly adapt to the environment, according to its dimensions. The ENG model analysis shows that the net evolves as a scale-free graph, and justifies in a deeply physical sense- the term gas here used.Comment: 16 pages, 8 figure