Design Space Exploration of Next-Generation HPC Machines

The landscape of High Performance Computing (HPC) system architectures keeps expanding with new technologies and increased complexity. With the goal of improving the efficiency of next-generation large HPC systems, designers require tools for analyzing and predicting the impact of new architectural features on the performance of complex scientific applications at scale. We simulate five hybrid (MPI+OpenMP) applications over 864 architectural proposals based on stateof-the-art and emerging HPC technologies, relevant both in industry and research. This paper significantly extends our previous work with MUltiscale Simulation Approach (MUSA) enabling accurate performance and power estimations of largescale HPC systems. We reveal that several applications present critical scalability issues mostly due to the software parallelization approach. Looking at speedup and energy consumption exploring the design space (i.e., changing memory bandwidth, number of cores, and type of cores), we provide evidence-based architectural recommendations that will serve as hardware and software codesign guidelines.Preprin

Developing High Performance Computing Resources for Teaching Cluster and Grid Computing courses

High-Performance Computing (HPC) and the ability to process large amounts of data are of paramount importance for UK business and economy as outlined by Rt Hon David Willetts MP at the HPC and Big Data conference in February 2014. However there is a shortage of skills and available training in HPC to prepare and expand the workforce for the HPC and Big Data research and development. Currently, HPC skills are acquired mainly by students and staff taking part in HPC-related research projects, MSc courses, and at the dedicated training centres such as Edinburgh University’s EPCC. There are few UK universities teaching the HPC, Clusters and Grid Computing courses at the undergraduate level. To address the issue of skills shortages in the HPC it is essential to provide teaching and training as part of both postgraduate and undergraduate courses. The design and development of such courses is challenging since the technologies and software in the fields of large scale distributed systems such as Cluster, Cloud and Grid computing are undergoing continuous change. The students completing the HPC courses should be proficient in these evolving technologies and equipped with practical and theoretical skills for future jobs in this fast developing area. In this paper we present our experience in developing the HPC, Cluster and Grid modules including a review of existing HPC courses offered at the UK universities. The topics covered in the modules are described, as well as the coursework projects based on practical laboratory work. We conclude with an evaluation based on our experience over the last ten years in developing and delivering the HPC modules on the undergraduate courses, with suggestions for future work

Research and Education in Computational Science and Engineering

Over the past two decades the field of computational science and engineering (CSE) has penetrated both basic and applied research in academia, industry, and laboratories to advance discovery, optimize systems, support decision-makers, and educate the scientific and engineering workforce. Informed by centuries of theory and experiment, CSE performs computational experiments to answer questions that neither theory nor experiment alone is equipped to answer. CSE provides scientists and engineers of all persuasions with algorithmic inventions and software systems that transcend disciplines and scales. Carried on a wave of digital technology, CSE brings the power of parallelism to bear on troves of data. Mathematics-based advanced computing has become a prevalent means of discovery and innovation in essentially all areas of science, engineering, technology, and society; and the CSE community is at the core of this transformation. However, a combination of disruptive developments---including the architectural complexity of extreme-scale computing, the data revolution that engulfs the planet, and the specialization required to follow the applications to new frontiers---is redefining the scope and reach of the CSE endeavor. This report describes the rapid expansion of CSE and the challenges to sustaining its bold advances. The report also presents strategies and directions for CSE research and education for the next decade.Comment: Major revision, to appear in SIAM Revie

Control of a train of high purity distillation columns for efficient production of 13C isotopes

It is well-known that high-purity distillation columns are difficult to control due to their ill-conditioned and strongly nonlinear behaviour. The fact that these processes are operated over a wide range of feed compositions and flow rates makes the control design even more challenging. This paper proposes the most suitable control strategies applicable to a series of cascaded distillation column processes. The conditions for control and input-output relations are discusssed in view of the global control strategy. The increase in complexity with increased number of series cascaded distillation column processes is tackled. Uncertainty in the model parameters is discussed with respect to the dynamics of the global train distillation process. The main outcome of this work is insight into the possible control methodologies for this particular class of distillation processes

The transformation of community hospitals through the transition to value-based care: Lessons from Massachusetts

Enabling community hospitals to provide efficient and effective care and maintain competition on par with their academic medical center (AMC) counterparts remain challenges for most states. Advancing accountable care readiness adds to the complexity of these challenges. Community hospitals experience narrower operating margins and more limited access to large populations than their AMC counterparts, making the shift to value-based care difficult. Massachusetts has taken legislative action to ensure a statewide focus on reducing healthcare costs, which includes a nearly $120-million grant program supporting community hospital and system transformation toward a value-based environment. The Massachusetts Health Policy Commission’s Community Hospital Acceleration, Revitalization and Transformation (CHART) investment program is the state’s largest effort to date aimed at readying community hospitals for value-based care. In doing so, Massachusetts has created the largest state-driven, all-payer (payer-blind) readmission reduction initiative in the country. n this paper, we examine the design and evolution of CHART Phases 1 and 2 and offer insights for other states contemplating innovative approaches to bolstering community hospital participation in value-based care models

The Strategy of the Commons: Modelling the Annual Cost of Successful ICT Services for European Research

The provision of ICT services for research is increasingly using Cloud services to complement the traditional federation of computing centres. Due to the complex funding structure and differences in the basic business model, comparing the cost-effectiveness of these options requires a new approach to cost assessment. This paper presents a cost assessment method addressing the limitations of the standard methods and some of the initial results of the study. This acts as an illustration of the kind of cost assessment issues high-utilisation rate ICT services should consider when choosing between different infrastructure options. The research is co-funded by the European Commission Seventh Framework Programme through the e-FISCAL project (contract number RI-283449)