140,466 research outputs found
Cell division: a source of active stress in cellular monolayers
We introduce the notion of cell division-induced activity and show that the
cell division generates extensile forces and drives dynamical patterns in cell
assemblies. Extending the hydrodynamic models of lyotropic active nematics we
describe turbulent-like velocity fields that are generated by the cell division
in a confluent monolayer of cells. We show that the experimentally measured
flow field of dividing Madin-Darby Canine Kidney (MDCK) cells is reproduced by
our modeling approach. Division-induced activity acts together with intrinsic
activity of the cells in extensile and contractile cell assemblies to change
the flow and director patterns and the density of topological defects. Finally
we model the evolution of the boundary of a cellular colony and compare the
fingering instabilities induced by cell division to experimental observations
on the expansion of MDCK cell cultures.Comment: Accepted Manuscript for Celebrating Soft Matter's 10th Anniversar
Performance of silicon solar cell assemblies
Solar cell assembly current-voltage characteristics, thermal-optical properties, and power performance were determined. Solar cell cover glass thermal radiation, optical properties, confidence limits, and temperature intensity effects on maximum power were discussed
Neural Mechanisms for Information Compression by Multiple Alignment, Unification and Search
This article describes how an abstract framework for perception and cognition may be realised in terms of neural mechanisms and neural processing.
This framework — called information compression by multiple alignment, unification and search (ICMAUS) — has been developed in previous research as a generalized model of any system for processing information, either natural or
artificial. It has a range of applications including the analysis and production of natural language, unsupervised inductive learning, recognition of objects and patterns, probabilistic reasoning, and others. The proposals in this article may be seen as an extension and development of
Hebb’s (1949) concept of a ‘cell assembly’.
The article describes how the concept of ‘pattern’ in the ICMAUS framework may be mapped onto a version of the cell
assembly concept and the way in which neural mechanisms may achieve the effect of ‘multiple alignment’ in the ICMAUS framework.
By contrast with the Hebbian concept of a cell assembly, it is proposed here that any one neuron can belong in one assembly and only one assembly. A key feature of present proposals, which is not part of the Hebbian concept, is that any cell assembly may contain ‘references’ or ‘codes’ that serve to identify one or more other cell assemblies. This mechanism allows information to be stored in a compressed form, it provides a robust mechanism by which assemblies may be connected to form hierarchies and other kinds of structure, it means that assemblies can express
abstract concepts, and it provides solutions to some of the other problems associated with cell assemblies.
Drawing on insights derived from the ICMAUS framework, the article also describes how learning may be achieved with neural mechanisms. This concept of learning is significantly different from the Hebbian concept and appears to provide a better account of what we know about human learning
Large area space solar cell assemblies
Development of a large area space solar cell assembly is presented. The assembly consists of an ion implanted silicon cell and glass cover. The important attributes of fabrication are (1) use of a back surface field which is compatible with a back surface reflector, and (2) integration of coverglass application and call fabrication
Sealing of silver oxide-zinc storage cells Quarterly report, 23 Dec. 1967 - 23 Mar. 1968
Performance test data on sealed assemblies of composite silver zinc cell and dual micro fuel cel
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