385 research outputs found

    NASA Capability Roadmaps Executive Summary

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    This document is the result of eight months of hard work and dedication from NASA, industry, other government agencies, and academic experts from across the nation. It provides a summary of the capabilities necessary to execute the Vision for Space Exploration and the key architecture decisions that drive the direction for those capabilities. This report is being provided to the Exploration Systems Architecture Study (ESAS) team for consideration in development of an architecture approach and investment strategy to support NASA future mission, programs and budget requests. In addition, it will be an excellent reference for NASA's strategic planning. A more detailed set of roadmaps at the technology and sub-capability levels are available on CD. These detailed products include key driving assumptions, capability maturation assessments, and technology and capability development roadmaps

    Characterization of Nanoparticle Batch-To-Batch Variability

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    A central challenge for the safe design of nanomaterials (NMs) is the inherent variability of NM properties, both as produced and as they interact with and evolve in, their surroundings. This has led to uncertainty in the literature regarding whether the biological and toxicological effects reported for NMs are related to specific NM properties themselves, or rather to the presence of impurities or physical effects such as agglomeration of particles. Thus, there is a strong need for systematic evaluation of the synthesis and processing parameters that lead to potential variability of different NM batches and the reproducible production of commonly utilized NMs. The work described here represents over three years of effort across 14 European laboratories to assess the reproducibility of nanoparticle properties produced by the same and modified synthesis routes for four of the OECD priority NMs (silica dioxide, zinc oxide, cerium dioxide and titanium dioxide) as well as amine-modified polystyrene NMs, which are frequently employed as positive controls for nanotoxicity studies. For 46 different batches of the selected NMs, all physicochemical descriptors as prioritized by the OECD have been fully characterized. The study represents the most complete assessment of NMs batch-to-batch variability performed to date and provides numerous important insights into the potential sources of variability of NMs and how these might be reduced

    Cell Culture

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    Cell culture is cell cloning technology that simulates in vivo environment conditions such as asepsis, appropriate temperature, and pH as well as certain nutritional conditions to enable cells to survive, grow, reproduce, and maintain their structure and function. Cell culture can be used to grow human, animal, plant, and microbial cells. Each type of cell culture has its own characteristics and essential conditions. This book focuses on the advanced technology and applications of cell culture in the research and practice of medical and life sciences. Chapters address such topics as primary cancer cell cultures, 2D and 3D cell cultures, stem cells, nanotechnology, and more

    Data Science-Based Full-Lifespan Management of Lithium-Ion Battery

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    This open access book comprehensively consolidates studies in the rapidly emerging field of battery management. The primary focus is to overview the new and emerging data science technologies for full-lifespan management of Li-ion batteries, which are categorized into three groups, namely (i) battery manufacturing management, (ii) battery operation management, and (iii) battery reutilization management. The key challenges, future trends as well as promising data-science technologies to further improve this research field are discussed. As battery full-lifespan (manufacturing, operation, and reutilization) management is a hot research topic in both energy and AI fields and none specific book has focused on systematically describing this particular from a data science perspective before, this book can attract the attention of academics, scientists, engineers, and practitioners. It is useful as a reference book for students and graduates working in related fields. Specifically, the audience could not only get the basics of battery manufacturing, operation, and reutilization but also the information of related data-science technologies. The step-by-step guidance, comprehensive introduction, and case studies to the topic make it accessible to audiences of different levels, from graduates to experienced engineers
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