A Novel Power-Efficient Wireless Multi-channel Recording System for the Telemonitoring of Electroencephalography (EEG)

This research introduces the development of a novel EEG recording system that is modular, batteryless, and wireless (untethered) with the supporting theoretical foundation in wireless communications and related design elements and circuitry. Its modular construct overcomes the EEG scaling problem and makes it easier for reconfiguring the hardware design in terms of the number and placement of electrodes and type of standard EEG system contemplated for use. In this development, portability, lightweight, and applicability to other clinical applications that rely on EEG data are sought. Due to printer tolerance, the 3D printed cap consists of 61 electrode placements. This recording capacity can however extend from 21 (as in the international 10-20 systems) up to 61 EEG channels at sample rates ranging from 250 to 1000 Hz and the transfer of the raw EEG signal using a standard allocated frequency as a data carrier. The main objectives of this dissertation are to (1) eliminate the need for heavy mounted batteries, (2) overcome the requirement for bulky power systems, and (3) avoid the use of data cables to untether the EEG system from the subject for a more practical and less restrictive setting. Unpredictability and temporal variations of the EEG input make developing a battery-free and cable-free EEG reading device challenging. Professional high-quality and high-resolution analog front ends are required to capture non-stationary EEG signals at microvolt levels. The primary components of the proposed setup are the wireless power transmission unit, which consists of a power amplifier, highly efficient resonant-inductive link, rectification, regulation, and power management units, as well as the analog front end, which consists of an analog to digital converter, pre-amplification unit, filtering unit, host microprocessor, and the wireless communication unit. These must all be compatible with the rest of the system and must use the least amount of power possible while minimizing the presence of noise and the attenuation of the recorded signal A highly efficient resonant-inductive coupling link is developed to decrease power transmission dissipation. Magnetized materials were utilized to steer electromagnetic flux and decrease route and medium loss while transmitting the required energy with low dissipation. Signal pre-amplification is handled by the front-end active electrodes. Standard bio-amplifier design approaches are combined to accomplish this purpose, and a thorough investigation of the optimum ADC, microcontroller, and transceiver units has been carried out. We can minimize overall system weight and power consumption by employing battery-less and cable-free EEG readout system designs, consequently giving patients more comfort and freedom of movement. Similarly, the solutions are designed to match the performance of medical-grade equipment. The captured electrical impulses using the proposed setup can be stored for various uses, including classification, prediction, 3D source localization, and for monitoring and diagnosing different brain disorders. All the proposed designs and supporting mathematical derivations were validated through empirical and software-simulated experiments. Many of the proposed designs, including the 3D head cap, the wireless power transmission unit, and the pre-amplification unit, are already fabricated, and the schematic circuits and simulation results were based on Spice, Altium, and high-frequency structure simulator (HFSS) software. The fully integrated head cap to be fabricated would require embedding the active electrodes into the 3D headset and applying current technological advances to miniaturize some of the design elements developed in this dissertation

Multi-channel ultra-low-power receiver architecture for body area networks

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 85-91).In recently published integrated medical monitoring systems, a common thread is the high power consumption of the radio compared to the other system components. This observation is indicative of a natural place to attempt a reduction in system power. Narrowband receivers in-particular can enjoy significant power reduction by employing high-Q bulk acoustic resonators as channel select filters directly at RF, allowing down-stream analog processing to be simplified, resulting in better energy efficiency. But for communications in the ISM bands, it is important to employ multiple frequency channels to permit frequency-division-multiplexing and provide frequency diversity in the face of narrowband interferers. The high-Q nature of the resonators means that frequency tuning to other channels in the same band is nearly impossible; hence, a new architecture is required to address this challenge. A multi-channel ultra-low power OOK receiver for Body Area Networks (BANs) has been designed and tested. The receiver multiplexes three Film Bulk Acoustic Resonators (FBARs) to provide three channels of frequency discrimination, while at the same time offering competitive sensitivity and superior energy efficiency in this class of BAN receivers. The high-Q parallel resonance of each resonator determines the passband. The resonator's Q is on the order of 1000 and its center frequency is approximately 2.5 GHz, resulting in a -3 dB bandwidth of roughly 2.5 MHz with a very steep rolloff. Channels are selected by enabling the corresponding LNA and mixer pathway with switches, but a key benefit of this architecture is that the switches are not in series with the resonator and do not de-Q the resonance. The measured 1E-3 sensitivity is -64 dBm at 1 Mbps for an energy efficiency of 180 pJ/bit. The resonators are packaged beside the CMOS using wirebonds for the prototype.by Phillip Michel Nadeau.S.M

Ultra-Low Power Wake Up Receiver For Medical Implant Communications Service Transceiver

This thesis explores the specific requirements and challenges for the design of a dedicated wake-up receiver for medical implant communication services equipped with a novel “uncertain-IF†architecture combined with a high – Q filtering MEMS resonator and a free running CMOS ring oscillator as the RF LO. The receiver prototype, implements an IBM 0.18μm mixed-signal 7ML RF CMOS technology and achieves a sensitivity of -62 dBm at 404MHz while consuming \u3c100 μW from a 1 V supply

RF MEMS reference oscillators platform for wireless communications

A complete platform for RF MEMS reference oscillator is built to replace bulky quartz from mobile devices, thus reducing size and cost. The design targets LTE transceivers. A low phase noise 76.8 MHz reference oscillator is designed using material temperature compensated AlN-on-silicon resonator. The thesis proposes a system combining piezoelectric resonator with low loading CMOS cross coupled series resonance oscillator to reach state-of-the-art LTE phase noise specifications. The designed resonator is a two port fundamental width extensional mode resonator. The resonator characterized by high unloaded quality factor in vacuum is designed with low temperature coefficient of frequency (TCF) using as compensation material which enhances the TCF from - 3000 ppm to 105 ppm across temperature ranges of -40˚C to 85˚C. By using a series resonant CMOS oscillator, phase noise of -123 dBc/Hz at 1 kHz, and -162 dBc/Hz at 1MHz offset is achieved. The oscillator’s integrated RMS jitter is 106 fs (10 kHz–20 MHz), consuming 850 μA, with startup time is 250μs, achieving a Figure-of-merit (FOM) of 216 dB. Electronic frequency compensation is presented to further enhance the frequency stability of the oscillator. Initial frequency offset of 8000 ppm and temperature drift errors are combined and further addressed electronically. A simple digital compensation circuitry generates a compensation word as an input to 21 bit MASH 1 -1-1 sigma delta modulator incorporated in RF LTE fractional N-PLL for frequency compensation. Temperature is sensed using low power BJT band-gap front end circuitry with 12 bit temperature to digital converter characterized by a resolution of 0.075˚C. The smart temperature sensor consumes only 4.6 μA. 700 MHz band LTE signal proved to have the stringent phase noise and frequency resolution specifications among all LTE bands. For this band, the achieved jitter value is 1.29 ps and the output frequency stability is 0.5 ppm over temperature ranges from -40˚C to 85˚C. The system is built on 32nm CMOS technology using 1.8V IO device

MICRO-ELECTRO-MECHANICAL SYSTEM OSCILLATING ACCELERAMETERS WITH CMOS READOUT CIRCUITS

Ph.DDOCTOR OF PHILOSOPH

Advancements in Superconducting Microwave Cavities and Qubits for Quantum Information Systems

Superconducting microwave cavities with ultra-high Q-factors are revolutionizing the field of quantum computing, offering long coherence times exceeding 1 ms, which is critical for realizing scalable multi-qubit quantum systems with low error rates. In this work, we provide an in-depth analysis of recent advances in ultra-high Q-factor cavities, integration of Josephson junction-based qubits, and bosonic-encoded qubits in 3D cavities. We examine the sources of quantum state dephasing caused by damping and noise mechanisms in cavities and qubits, highlighting the critical challenges that need to be addressed to achieve even higher coherence times. We critically survey the latest progress made in implementing single 3D qubits using superconducting materials, normal metals, and multi-qubit and multi-state quantum systems. Our work sheds light on the promising future of this research area, including novel materials for cavities and qubits, modes with nontrivial topological properties, error correction techniques for bosonic qubits, and new light-matter interaction effects

The effects of mechanical coupling on the electrical impedance of MEMS resonators for UHF filter applications

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2004.Includes bibliographical references (p. 137-138).(cont.) This thesis presents finite elements based simulations of electromechanical transfer functions for resonator and filter geometries. These Finite Element Analysis (FEA) simulations are performed using the ANSYS software and demonstrate the significance of mechanical coupling between MEMS longitudinal-mode bar (L-Bar) resonators. An analytical model and equivalent circuit are derived for a single L-Bar resonator. The analytical derivation is validated with an FEA model having the same material parameters and boundary conditions. The center frequency and resonant impedance produced by the FEA model are within 1% of the analytical values. A boundary condition study is undertaken to determine the sensitivity of the L-Bar resonator model to changes in the peripheral geometry and displacement constraints. A comparison of FEA results indicates that a simple resonator model with only tether supports yields impedance and center frequency values comparable to those of more complex geometries. When compared to initial experimental results from an actual resonator, the simulated electrical output corresponds well to the actual transfer function. This study also introduces a method for calculating the parameters of the resonator's equivalent circuit model from simulated (or measured) transfer function data. The method is tested on simulation data for which a mechanical Quality factor is designated. Comparing the prescribed mechanical Q to the extracted circuit Q provides a consistency check for the technique. The parameter extraction technique is a useful first attempt to devise a comprehensive method for determining circuit parameters that will reliably reproduce the transfer function of an actual resonator. Finally, a new resonator topology(cont.) is presented that employs mechanical coupling between L-Bar resonators to improve upon the output of a single bar and create alternative configurations for filter design at Draper. The new coupled bar geometry can be configured as either a single-port resonator or a multi-port filter. The benefits of mechanical coupling are investigated for both configurations. In discussion of future work, optimized filter parameters are presented, along with suggestions for achieving these values.by Luke A. Hohreiter.S.M

Digitally-assisted, ultra-low power circuits and systems for medical applications

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.Cataloged from PDF version of thesis.Includes bibliographical references (p. 219-225).In recent years, trends in the medical industry have created a growing demand for a variety of implantable medical devices. At the same time, advances in integrated circuits techniques, particularly in CMOS, have opened possibilities for advanced implantable systems that are very small and consume minimal energy. Minimizing the volume of medical implants is important as it allows for less invasive procedures and greater comfort to patients. Minimizing energy consumption is imperative as batteries must last at least a decade without replacement. Two primary functions that consume energy in medical implants are sensor interfaces that collect information from biomedical signals, and radios that allow the implant to communicate with a base-station outside of the body. The general focus of this work was the development of circuits and systems that minimize the size and energy required to carry out these two functions. The first part of this work focuses on laying down the theoretical framework for an ultra-low power radio, including advances to the literature in the area of super-regeneration. The second part includes the design of a transceiver optimized for medical implants, and its implementation in a CMOS process. The final part describes the design of a sensor interface that leverages novel analog and digital techniques to reduce the system's size and improve its functionality. This final part was developed in conjunction with Marcus Yip.by Jose L. Bohorquez.Ph.D

A low power, low noise, 1.8 GHz voltage-controlled oscillator

Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997.Includes bibliographical references (leaf 97).by Donald A. Hitko.M.S