674 research outputs found
Abstract State Machines 1988-1998: Commented ASM Bibliography
An annotated bibliography of papers which deal with or use Abstract State
Machines (ASMs), as of January 1998.Comment: Also maintained as a BibTeX file at http://www.eecs.umich.edu/gasm
A Note on Efficient Computation of All Abelian Periods in a String
We derive a simple efficient algorithm for Abelian periods knowing all
Abelian squares in a string. An efficient algorithm for the latter problem was
given by Cummings and Smyth in 1997. By the way we show an alternative
algorithm for Abelian squares. We also obtain a linear time algorithm finding
all `long' Abelian periods. The aim of the paper is a (new) reduction of the
problem of all Abelian periods to that of (already solved) all Abelian squares
which provides new insight into both connected problems
On the possible Computational Power of the Human Mind
The aim of this paper is to address the question: Can an artificial neural
network (ANN) model be used as a possible characterization of the power of the
human mind? We will discuss what might be the relationship between such a model
and its natural counterpart. A possible characterization of the different power
capabilities of the mind is suggested in terms of the information contained (in
its computational complexity) or achievable by it. Such characterization takes
advantage of recent results based on natural neural networks (NNN) and the
computational power of arbitrary artificial neural networks (ANN). The possible
acceptance of neural networks as the model of the human mind's operation makes
the aforementioned quite relevant.Comment: Complexity, Science and Society Conference, 2005, University of
Liverpool, UK. 23 page
The Tandem Duplication Distance Is NP-Hard
In computational biology, tandem duplication is an important biological phenomenon which can occur either at the genome or at the DNA level. A tandem duplication takes a copy of a genome segment and inserts it right after the segment - this can be represented as the string operation AXB ? AXXB. Tandem exon duplications have been found in many species such as human, fly or worm, and have been largely studied in computational biology.
The Tandem Duplication (TD) distance problem we investigate in this paper is defined as follows: given two strings S and T over the same alphabet, compute the smallest sequence of tandem duplications required to convert S to T. The natural question of whether the TD distance can be computed in polynomial time was posed in 2004 by Leupold et al. and had remained open, despite the fact that tandem duplications have received much attention ever since. In this paper, we prove that this problem is NP-hard, settling the 16-year old open problem. We further show that this hardness holds even if all characters of S are distinct. This is known as the exemplar TD distance, which is of special relevance in bioinformatics. One of the tools we develop for the reduction is a new problem called the Cost-Effective Subgraph, for which we obtain W[1]-hardness results that might be of independent interest. We finally show that computing the exemplar TD distance between S and T is fixed-parameter tractable. Our results open the door to many other questions, and we conclude with several open problems
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