20,459 research outputs found
Pediatric Bone Age Assessment Using Deep Convolutional Neural Networks
Skeletal bone age assessment is a common clinical practice to diagnose
endocrine and metabolic disorders in child development. In this paper, we
describe a fully automated deep learning approach to the problem of bone age
assessment using data from Pediatric Bone Age Challenge organized by RSNA 2017.
The dataset for this competition is consisted of 12.6k radiological images of
left hand labeled by the bone age and sex of patients. Our approach utilizes
several deep learning architectures: U-Net, ResNet-50, and custom VGG-style
neural networks trained end-to-end. We use images of whole hands as well as
specific parts of a hand for both training and inference. This approach allows
us to measure importance of specific hand bones for the automated bone age
analysis. We further evaluate performance of the method in the context of
skeletal development stages. Our approach outperforms other common methods for
bone age assessment.Comment: 14 pages, 9 figure
Semi-Supervised Self-Taught Deep Learning for Finger Bones Segmentation
Segmentation stands at the forefront of many high-level vision tasks. In this
study, we focus on segmenting finger bones within a newly introduced
semi-supervised self-taught deep learning framework which consists of a student
network and a stand-alone teacher module. The whole system is boosted in a
life-long learning manner wherein each step the teacher module provides a
refinement for the student network to learn with newly unlabeled data.
Experimental results demonstrate the superiority of the proposed method over
conventional supervised deep learning methods.Comment: IEEE BHI 2019 accepte
Multimodal Machine Learning-based Knee Osteoarthritis Progression Prediction from Plain Radiographs and Clinical Data
Knee osteoarthritis (OA) is the most common musculoskeletal disease without a
cure, and current treatment options are limited to symptomatic relief.
Prediction of OA progression is a very challenging and timely issue, and it
could, if resolved, accelerate the disease modifying drug development and
ultimately help to prevent millions of total joint replacement surgeries
performed annually. Here, we present a multi-modal machine learning-based OA
progression prediction model that utilizes raw radiographic data, clinical
examination results and previous medical history of the patient. We validated
this approach on an independent test set of 3,918 knee images from 2,129
subjects. Our method yielded area under the ROC curve (AUC) of 0.79 (0.78-0.81)
and Average Precision (AP) of 0.68 (0.66-0.70). In contrast, a reference
approach, based on logistic regression, yielded AUC of 0.75 (0.74-0.77) and AP
of 0.62 (0.60-0.64). The proposed method could significantly improve the
subject selection process for OA drug-development trials and help the
development of personalized therapeutic plans
A Survey on Deep Learning in Medical Image Analysis
Deep learning algorithms, in particular convolutional networks, have rapidly
become a methodology of choice for analyzing medical images. This paper reviews
the major deep learning concepts pertinent to medical image analysis and
summarizes over 300 contributions to the field, most of which appeared in the
last year. We survey the use of deep learning for image classification, object
detection, segmentation, registration, and other tasks and provide concise
overviews of studies per application area. Open challenges and directions for
future research are discussed.Comment: Revised survey includes expanded discussion section and reworked
introductory section on common deep architectures. Added missed papers from
before Feb 1st 201
Assessing knee OA severity with CNN attention-based end-to-end architectures
This work proposes a novel end-to-end convolutional neural network (CNN) architecture to automatically quantify the severity of knee osteoarthritis (OA) using X-Ray images, which incorporates trainable attention modules acting as unsupervised fine-grained detectors of the region of interest (ROI). The proposed attention modules can be applied at different levels and scales across any CNN pipeline helping the network to learn relevant attention patterns over the most informative parts of the image at different resolutions. We test the proposed attention mechanism on existing state-of-the-art CNN architectures as our base models, achieving promising results on the benchmark knee OA datasets from the osteoarthritis initiative (OAI) and multicenter osteoarthritis study (MOST).Postprint (published version
- …