Designing and Solving Location-Routing-Allocation Problems in a Sustainable Blood Supply Chain Network of Blood Transport in Uncertainty Conditions

Purpose: In this paper, a location-routing-allocation problem in a multi-objective blood supply chain network was designed to reduce the total cost of the supply chain network, the maximum unmet demand from distribution of goods, and decline greenhouse gas emissions due to the transport of goods among different levels of the network. The network levels considered for modeling include blood donation clusters, permanent and temporary blood transfusion centers, major laboratory centers and blood supply points. Other objectives included determining the optimal number and location of potential facilities, optimal allocation of the flow of goods between the selected facilities and determining the most suitable transport route to distribute the goods to customer areas in uncertainty conditions. Methodology: Given that the model was NP-hard, the NSGA II and MOPSO algorithms were used to solve the model with a priority-based solution. Findings: The results of the design of the experiments showed the high efficiency of the NSGA II algorithm in comparison with the MOPSO algorithm in finding efficient solutions. Originality/Value: This study addresses the issue of blood perishability from blood sampling to distribution to customer demand areas

Robust Platelet Logistics Planning in Disaster Relief Operations Under Uncertainty: a Coordinated Approach

© 2017, Springer Science+Business Media, LLC. Resource sharing, as a coordination mechanism, can mitigate disruptions in supply and changes in demand. It is particularly crucial for platelets because they have a short lifespan and need to be transferred and allocated within a limited time to prevent waste or shortages. Thus, a coordinated model comprised of a mixed vertical-horizontal structure, for the logistics of platelets, is proposed for disaster relief operations in the response phase. The aim of this research is to reduce the wastage and shortage of platelets due to their critical role in wound healing. We present a bi-objective location-allocation robust possibilistic programming model for designing a two-layer coordinated organization strategy for multi-type blood-derived platelets under demand uncertainty. Computational results, derived using a heuristic ε-constraint algorithm, are reported and discussed to show the applicability of the proposed model. The experimental results indicate that surpluses and shortages in platelets remarkably declined following instigation of a coordinated disaster relief operation

Optimization strategies for the integrated management of perishable supply chains: A literature review

Purpose: The main purpose of this article is to systematically review the papers published in the period 2005-2020 about the integration of production, inventory and distribution activities in perishable supply chains. Design/methodology/approach: The proposed research methodology is based on several steps. First, database and keywords are selected, with the aim to search and collect the main papers, dealing with the integration of production, inventory, distribution activities in perishable supply chains. Then, a bibliometric analysis is carried out, to detect: the main publishing sources, the chronological distribution, the most used keywords, the featured authors, about the selected papers. A five-dimension classification framework is proposed to carry out a content analysis, where the papers of the literature review are classified and discussed, according to: supply chain structure, objective, perishability type, solution approach, approach validation. Findings: Interest in the application of optimization models for integrated decision-making along perishable supply chains is strongly growing. Integrating multiple stages of the supply chain into a single framework is complex, especially when referring to perishable products. The vast majority of the problems addressed are then NP-Hard. Only a limited quantity of the selected papers aims to solve real-life case studies. There is a need for further research, which is capable of modeling and quantitatively improving existing supply chains. The potentials of Industry 4.0 are currently little explored. Originality/value: Based on the analysis of the papers published, this article outlines the current state of the art on the optimization strategies for the integrated management of perishable supply chains, which are very complex to be managed. Research trends and gaps are discussed, future challenges are presentedPeer Reviewe

An Optimisation-based Framework for Complex Business Process: Healthcare Application

The Irish healthcare system is currently facing major pressures due to rising demand, caused by population growth, ageing and high expectations of service quality. This pressure on the Irish healthcare system creates a need for support from research institutions in dealing with decision areas such as resource allocation and performance measurement. While approaches such as modelling, simulation, multi-criteria decision analysis, performance management, and optimisation can – when applied skilfully – improve healthcare performance, they represent just one part of the solution. Accordingly, to achieve significant and sustainable performance, this research aims to develop a practical, yet effective, optimisation-based framework for managing complex processes in the healthcare domain. Through an extensive review of the literature on the aforementioned solution techniques, limitations of using each technique on its own are identified in order to define a practical integrated approach toward developing the proposed framework. During the framework validation phase, real-time strategies have to be optimised to solve Emergency Department performance issues in a major hospital. Results show a potential of significant reduction in patients average length of stay (i.e. 48% of average patient throughput time) whilst reducing the over-reliance on overstretched nursing resources, that resulted in an increase of staff utilisation between 7% and 10%. Given the high uncertainty in healthcare service demand, using the integrated framework allows decision makers to find optimal staff schedules that improve emergency department performance. The proposed optimum staff schedule reduces the average waiting time of patients by 57% and also contributes to reduce number of patients left without treatment to 8% instead of 17%. The developed framework has been implemented by the hospital partner with a high level of success

Dynamic temporary blood facility location-allocation during and post-disaster periods

The key objective of this study is to develop a tool (hybridization or integration of different techniques) for locating the temporary blood banks during and post-disaster conditions that could serve the hospitals with minimum response time. We have used temporary blood centers, which must be located in such a way that it is able to serve the demand of hospitals in nearby region within a shorter duration. We are locating the temporary blood centres for which we are minimizing the maximum distance with hospitals. We have used Tabu search heuristic method to calculate the optimal number of temporary blood centres considering cost components. In addition, we employ Bayesian belief network to prioritize the factors for locating the temporary blood facilities. Workability of our model and methodology is illustrated using a case study including blood centres and hospitals surrounding Jamshedpur city. Our results shows that at-least 6 temporary blood facilities are required to satisfy the demand of blood during and post-disaster periods in Jamshedpur. The results also show that that past disaster conditions, response time and convenience for access are the most important factors for locating the temporary blood facilities during and post-disaster periods

Developing Model Of Closed Loop Supply Chain Network For Subsidized Lpg 3-Kgs In East Java-Indonesia

Demand of subsidized LPG 3-kgs in Indonesia has been increasing since the Indonesian government imposed a conversion program from kerosene to Liquefied Petroleum Gas (LPG) in 2007. The high increase in demand for subsidized LPG 3-kgs led to the scarcity of products availability. The design of a closed distribution system is required to ensure the availability of subsidized LPG 3-kgs. In this research, the development model of the integration of closed loop supply chain network and vehicle routing problem with simultaneous deliveries and pick-ups with time windows has been proposed. The mechanism of closed distribution system starts from the distributors send LPG empty tubes to filling stations. After filling station inspected and filled the LPG tubes, distributors delivered LPG 3-kgs subsidized from the filling station to some retailers. At the same time, the distributors take back the empty tubes from these retailers by considering the limitations of operational time in each retailers. The proposed model was tested on numerical example and analyzed the result