You Can't Go Home Again - or Can you? 'Replication' Indeterminacy and 'Location' Incommensurability in Three Biological Re-Surveys

Reproducing empirical results and repeating experimental processes is fundamental to science, but is of grave concern to scientists. Revisiting the same location is necessary for tracking biological processes, yet I argue that ‘location’ and ‘replication’ contain a basic ambiguity. The analysis of the practical meanings of ‘replication’ and ‘location’ will strip of incommensurability from its common conflation with empirical equivalence, underdetermination and indeterminacy of reference. In particular, I argue that three biodiversity re-surveys, conducted by the research institutions of Harvard, Berkeley, and Hamaarag, all reveal incommensurability without indeterminacy in the smallest spatial scale, and indeterminacy without incommensurability in higher scales

You Can't Go Home Again - or Can you? 'Replication' Indeterminacy and 'Location' Incommensurability in Three Biological Re-Surveys

Reproducing empirical results and repeating experimental processes is fundamental to science, but is of grave concern to scientists. Revisiting the same location is necessary for tracking biological processes, yet I argue that ‘location’ and ‘replication’ contain a basic ambiguity. The analysis of the practical meanings of ‘replication’ and ‘location’ will strip of incommensurability from its common conflation with empirical equivalence, underdetermination and indeterminacy of reference. In particular, I argue that three biodiversity re-surveys, conducted by the research institutions of Harvard, Berkeley, and Hamaarag, all reveal incommensurability without indeterminacy in the smallest spatial scale, and indeterminacy without incommensurability in higher scales

The Eternal Unprovability Filter – Part I

I prove both the mathematical conjectures P ≠ NP and the Continuum Hypothesis are eternally unprovable using the same fundamental idea. Starting with the Saunders Maclane idea that a proof is eternal or it is not a proof, I use the indeterminacy of human biological capabilities in the eternal future to show that since both conjectures are independent of Axioms and have definitions connected with human biological capabilities, it would be impossible to prove them eternally without the creation and widespread acceptance of new axioms. I also show that the same fundamental concepts cannot be used to demonstrate the eternal unprovability of many other mathematical theorems and open conjectures. Finally I investigate the idea’s implications for the foundations of mathematics including its relation to Godel’s Incompleteness Theorem and Tarsky’s Undefinability Theorem

Jamesian Free Will, The Two-stage Model Of William James

Research into two-stage models of “free will” – first “free” random generation of alternative possibilities, followed by “willed” adequately determined decisions consistent with character, values, and desires – suggests that William James was in 1884 the first of a dozen philosophers and scientists to propose such a two-stage model for free will. We review the later work to establish James’s priority. By limiting chance to the generation of alternative possibilities, James was the first to overcome the standard two-part argument against free will, i.e., that the will is either determined or random. James gave it elements of both, to establish freedom but preserve responsibility. We show that James was influenced by Darwin’s model of natural selection, as were most recent thinkers with a two-stage model. In view of James’s famous decision to make his first act of freedom a choice to believe that his will is free, it is most fitting to celebrate James’s priority in the free will debates by naming the two-stage model – first chance, then choice -“Jamesian” free will

Internal Perspectivalism: The Solution to Generality Problems About Proper Function and Natural Norms

In this paper, I argue that what counts as the proper function of a trait is a matter of the de facto perspective that the biological system, itself, possesses on what counts as proper functioning for that trait. Unlike non-perspectival accounts, internal perspectivalism does not succumb to generality problems. But unlike external perspectivalism, internal perspectivalism can provide a fully naturalistic, mind-independent grounding of proper function and natural norms. The attribution of perspectives to biological systems is intended to be neither metaphorical nor anthropomorphic: I do not mean to imply that such systems thereby must possess agency, cognition, intentions, concepts, or mental or psychological states. Instead, such systems provide the grounding for norms of performance when they internally enforce their own standard of (i.e., their own perspective on) what constitutes proper functioning or malfunctioning. By operating with a fixed, determinate level of generality, such systems provide the basis for an account of proper function that is immune to generality problems

Building a cell and anatomy ontology of Caenorhabditis elegans

We are endowed with a rich knowledge about Caenorhabditis elegans. Its stereotyped anatomy and development has stimulated research and resulted in the accumulation of cell-based information concerning gene expression, and the role of specific cells in developmental signalling and behavioural circuits. To make the information more accessible to sophisticated queries and automated retrieval systems, WormBase has begun to construct a C. elegans cell and anatomy ontology. Here we present our strategies and progress