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Shape-driven segmentation of the arterial wall in intravascular ultrasound images
Segmentation of arterial wall boundaries from intravascular images is an important problem for many applications in the study of plaque characteristics, mechanical properties of the arterial wall, its 3D reconstruction,
and its measurements such as lumen size, lumen radius, and wall radius. We present a shape-driven approach to segmentation of the arterial wall from intravascular ultrasound images in the rectangular domain. In a properly built
shape space using training data, we constrain the lumen and media-adventitia contours to a smooth, closed geometry, which increases the segmentation quality without any tradeoff with a regularizer term. In addition to a shape prior,
we utilize an intensity prior through a non-parametric probability density based image energy, with global image measurements rather than pointwise measurements used in previous methods. Furthermore, a detection step is included to address the challenges introduced to the segmentation process by side branches and calcifications. All these features greatly enhance our segmentation method. The tests of our algorithm on a large dataset demonstrate the effectiveness of our approach
Quantum Image Processing and Its Application to Edge Detection: Theory and Experiment
Processing of digital images is continuously gaining in volume and relevance,
with concomitant demands on data storage, transmission and processing power.
Encoding the image information in quantum-mechanical systems instead of
classical ones and replacing classical with quantum information processing may
alleviate some of these challenges. By encoding and processing the image
information in quantum-mechanical systems, we here demonstrate the framework of
quantum image processing, where a pure quantum state encodes the image
information: we encode the pixel values in the probability amplitudes and the
pixel positions in the computational basis states. Our quantum image
representation reduces the required number of qubits compared to existing
implementations, and we present image processing algorithms that provide
exponential speed-up over their classical counterparts. For the commonly used
task of detecting the edge of an image, we propose and implement a quantum
algorithm that completes the task with only one single-qubit operation,
independent of the size of the image. This demonstrates the potential of
quantum image processing for highly efficient image and video processing in the
big data era.Comment: 13 pages, including 9 figures and 5 appendixe
Deep Learning in Cardiology
The medical field is creating large amount of data that physicians are unable
to decipher and use efficiently. Moreover, rule-based expert systems are
inefficient in solving complicated medical tasks or for creating insights using
big data. Deep learning has emerged as a more accurate and effective technology
in a wide range of medical problems such as diagnosis, prediction and
intervention. Deep learning is a representation learning method that consists
of layers that transform the data non-linearly, thus, revealing hierarchical
relationships and structures. In this review we survey deep learning
application papers that use structured data, signal and imaging modalities from
cardiology. We discuss the advantages and limitations of applying deep learning
in cardiology that also apply in medicine in general, while proposing certain
directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table
Graph analysis of functional brain networks: practical issues in translational neuroscience
The brain can be regarded as a network: a connected system where nodes, or
units, represent different specialized regions and links, or connections,
represent communication pathways. From a functional perspective communication
is coded by temporal dependence between the activities of different brain
areas. In the last decade, the abstract representation of the brain as a graph
has allowed to visualize functional brain networks and describe their
non-trivial topological properties in a compact and objective way. Nowadays,
the use of graph analysis in translational neuroscience has become essential to
quantify brain dysfunctions in terms of aberrant reconfiguration of functional
brain networks. Despite its evident impact, graph analysis of functional brain
networks is not a simple toolbox that can be blindly applied to brain signals.
On the one hand, it requires a know-how of all the methodological steps of the
processing pipeline that manipulates the input brain signals and extract the
functional network properties. On the other hand, a knowledge of the neural
phenomenon under study is required to perform physiological-relevant analysis.
The aim of this review is to provide practical indications to make sense of
brain network analysis and contrast counterproductive attitudes
Virtual Audio - Three-Dimensional Audio in Virtual Environments
Three-dimensional interactive audio has a variety ofpotential uses in human-machine interfaces. After lagging seriously
behind the visual components, the importance of sound is now becoming
increas-ingly accepted.
This paper mainly discusses background and techniques to implement
three-dimensional audio in computer interfaces. A case study of a
system for three-dimensional audio, implemented by the author, is
described in great detail. The audio system was moreover integrated
with a virtual reality system and conclusions on user tests and use
of the audio system is presented along with proposals for future work
at the end of the paper.
The thesis begins with a definition of three-dimensional audio and a
survey on the human auditory system to give the reader the needed
knowledge of what three-dimensional audio is and how human auditory
perception works
Acetylcholine neuromodulation in normal and abnormal learning and memory: vigilance control in waking, sleep, autism, amnesia, and Alzheimer's disease
This article provides a unified mechanistic neural explanation of how learning, recognition, and cognition break down during Alzheimer's disease, medial temporal amnesia, and autism. It also clarifies whey there are often sleep disturbances during these disorders. A key mechanism is how acetylcholine modules vigilance control in cortical layer
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