Datamining for Web-Enabled Electronic Business Applications

Web-Enabled Electronic Business is generating massive amount of data on customer purchases, browsing patterns, usage times and preferences at an increasing rate. Data mining techniques can be applied to all the data being collected for obtaining useful information. This chapter attempts to present issues associated with data mining for web-enabled electronic-business

A Survey of Parallel Data Mining

With the fast, continuous increase in the number and size of databases, parallel data mining is a natural and cost-effective approach to tackle the problem of scalability in data mining. Recently there has been a considerable research on parallel data mining. However, most projects focus on the parallelization of a single kind of data mining algorithm/paradigm. This paper surveys parallel data mining with a broader perspective. More precisely, we discuss the parallelization of data mining algorithms of four knowledge discovery paradigms, namely rule induction, instance-based learning, genetic algorithms and neural networks. Using the lessons learned from this discussion, we also derive a set of heuristic principles for designing efficient parallel data mining algorithms

On the combination of omics data for prediction of binary outcomes

Enrichment of predictive models with new biomolecular markers is an important task in high-dimensional omic applications. Increasingly, clinical studies include several sets of such omics markers available for each patient, measuring different levels of biological variation. As a result, one of the main challenges in predictive research is the integration of different sources of omic biomarkers for the prediction of health traits. We review several approaches for the combination of omic markers in the context of binary outcome prediction, all based on double cross-validation and regularized regression models. We evaluate their performance in terms of calibration and discrimination and we compare their performance with respect to single-omic source predictions. We illustrate the methods through the analysis of two real datasets. On the one hand, we consider the combination of two fractions of proteomic mass spectrometry for the calibration of a diagnostic rule for the detection of early-stage breast cancer. On the other hand, we consider transcriptomics and metabolomics as predictors of obesity using data from the Dietary, Lifestyle, and Genetic determinants of Obesity and Metabolic syndrome (DILGOM) study, a population-based cohort, from Finland