15,621 research outputs found
A closed-form approach to Bayesian inference in tree-structured graphical models
We consider the inference of the structure of an undirected graphical model
in an exact Bayesian framework. More specifically we aim at achieving the
inference with close-form posteriors, avoiding any sampling step. This task
would be intractable without any restriction on the considered graphs, so we
limit our exploration to mixtures of spanning trees. We consider the inference
of the structure of an undirected graphical model in a Bayesian framework. To
avoid convergence issues and highly demanding Monte Carlo sampling, we focus on
exact inference. More specifically we aim at achieving the inference with
close-form posteriors, avoiding any sampling step. To this aim, we restrict the
set of considered graphs to mixtures of spanning trees. We investigate under
which conditions on the priors - on both tree structures and parameters - exact
Bayesian inference can be achieved. Under these conditions, we derive a fast an
exact algorithm to compute the posterior probability for an edge to belong to
{the tree model} using an algebraic result called the Matrix-Tree theorem. We
show that the assumption we have made does not prevent our approach to perform
well on synthetic and flow cytometry data
Joint Structure Learning of Multiple Non-Exchangeable Networks
Several methods have recently been developed for joint structure learning of
multiple (related) graphical models or networks. These methods treat individual
networks as exchangeable, such that each pair of networks are equally
encouraged to have similar structures. However, in many practical applications,
exchangeability in this sense may not hold, as some pairs of networks may be
more closely related than others, for example due to group and sub-group
structure in the data. Here we present a novel Bayesian formulation that
generalises joint structure learning beyond the exchangeable case. In addition
to a general framework for joint learning, we (i) provide a novel default prior
over the joint structure space that requires no user input; (ii) allow for
latent networks; (iii) give an efficient, exact algorithm for the case of time
series data and dynamic Bayesian networks. We present empirical results on
non-exchangeable populations, including a real data example from biology, where
cell-line-specific networks are related according to genomic features.Comment: To appear in Proceedings of the Seventeenth International Conference
on Artificial Intelligence and Statistics (AISTATS
Incomplete graphical model inference via latent tree aggregation
Graphical network inference is used in many fields such as genomics or
ecology to infer the conditional independence structure between variables, from
measurements of gene expression or species abundances for instance. In many
practical cases, not all variables involved in the network have been observed,
and the samples are actually drawn from a distribution where some variables
have been marginalized out. This challenges the sparsity assumption commonly
made in graphical model inference, since marginalization yields locally dense
structures, even when the original network is sparse. We present a procedure
for inferring Gaussian graphical models when some variables are unobserved,
that accounts both for the influence of missing variables and the low density
of the original network. Our model is based on the aggregation of spanning
trees, and the estimation procedure on the Expectation-Maximization algorithm.
We treat the graph structure and the unobserved nodes as missing variables and
compute posterior probabilities of edge appearance. To provide a complete
methodology, we also propose several model selection criteria to estimate the
number of missing nodes. A simulation study and an illustration flow cytometry
data reveal that our method has favorable edge detection properties compared to
existing graph inference techniques. The methods are implemented in an R
package
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