The Effectiveness and Cost-Effectiveness of Screening Strategies for Breast Cancer in Indonesia

An informed decision-making based on suitable cost-effectiveness analysis is needed to better inform policy options for maximizing health outcomes and further scaling-up of services of breast cancer early detection program in Indonesia. The findings from this study address existing knowledge gaps and provide recommendations for future policy and research. The inclusion of relevant stakeholders throughout this research has been important in increasing the research quality and supporting the translation of research into policy and practice

Mineral Resources: Stocks, Flows, and Prospects

This chapter focuses on metals as they provide the clearest example of the challenges and opportunities that mineral resources present to society, in terms of both primary production and recycling. Basic concepts, information requirements and sources of consumer and industrial resource demand are described as well as the destabilizing effects of volatile resource prices and supply chain disruptions. Challenges facing extraction of in-ground resources and production of secondary resources are discussed and scenarios for the future considered. The results of the scenarios indicate that particularly energy and, as well, water and land requirements could become increasingly constraining factors for metal production. Key research questions are posed and modeling and data priorities discussed, with an emphasis on areas that require novel concepts and analytic tools to help lessen negative environmental impacts associated with minerals. The challenge of sustainability requires collaboration of practitioners and analysts with a multidisciplinary understanding of a broad set of issues, including economics, engineering, geology, ecology, and mathematical modeling, to name a few, as well as policy formulation and implementation.

Designing behavior change support systems in the context of knowledge documentation: development of theory and practical implementation

Although innovation and operating efficiently require creating, transferring, and applying knowledge, successful knowledge documentation remains a challenge for organizations. While knowledge management systems support knowledge management activities, the missing link to applying knowledge management relies on human actions and their behaviors. This dissertation extends prior design knowledge about designing Behavior Change Support Systems in the context of knowledge documentation by developing theory and showing practical implementation. Combining technical and psychological models within information systems frameworks based on the principles of abstraction, originality, justification, and benefit, this dissertation draws on design science to propose prescriptive knowledge, for example, in the form of design principles and a specific artifact

Sustainable Assessment in Supply Chain and Infrastructure Management

In the competitive business environment or public domain, the sustainability assessment in supply chain and infrastructure management are important for any organization. Organizations are currently striving to improve their sustainable strategies through preparedness, response, and recovery because of increasing competitiveness, community, and regulatory pressure. Thus, it is necessary to develop a meaningful and more focused understanding of sustainability in supply chain management and infrastructure management practices. In the context of a supply chain, sustainability implies that companies identify, assess, and manage impacts and risks in all the echelons of the supply chain, considering downstream and upstream activities. Similarly, the sustainable infrastructure management indicates the ability of infrastructure to meet the requirements of the present without sacrificing the ability of future generations to address their needs. The complexities regarding sustainable supply chain and infrastructure management have driven managers and professionals to seek different solutions. This Special Issue aims to provide readers with the most recent research results on the aforementioned subjects. In addition, it offers some solutions and also raises some questions for further research and development toward sustainable supply chain and infrastructure management

Porting and tuning of the Mont-Blanc benchmarks to the multicore ARM 64bit architecture

This project is about porting and tuning the Mont-Blanc benchmarks to the multicore ARM 64 bits architecture. The Mont-Blanc benchmarks are part of the Mont-Blanc European project and they have been developed internally in the BSC (Barcelona Supercomputing Center). The project will explore the possibilities that an ARM architecture can offer running in a HPC (High Performance Computing) setup, this includes to learn how to tune and adapt a parallelized computer program and analyze its execution behavior. As part of the project, we will analyze the performance of each benchmark using instrumentation tools such like Extrae and Paraver. Each benchmark will be adapted, tuned and executed mainly in the three new Mont-Blanc mini-clusters, Thunder (ARMv8 custom), Merlin (ARMv8 custom) and Jetson TX (ARMv8 cortex-a57) using the OmpSs programming model. The evolution of the performance obtained will be shown followed by a brief analysis of the results after each optimization.Aquest projecte es basa en adaptar i afinar els Mont-Blanc benchmarks a l’arquitectura multinucli ARM 64 bits. Els Mont-Blanc benchmarks formen part del projecte Europeu Mont-Blanc i han estat desenvolupats internament en el BSC (Barcelona Supercomputing Center). Aquest projecte explorarà el potencial d’usar l’arquitectura ARM en un entorn HPC (High Performance Computing), això inclou aprendre a adaptar i afinar un programa paral·lel, i analitzar el seu comportament durant l’execució. Com a part del projecte, s’analitzarà el rendiment de cada benchmark usant eines d’instrumentació com Extrae o Paraver. Cada benchmark serà adaptat, afinat i executat en els tres nous miniclústers de Mont-Blanc, Thunder (ARMv8 personalitzat), Merlin (ARMv8 personalitzat) i Jetson TX (ARMv8 cortex-a57) usant el model de programació OmpSs. Es mostrarà l’evolució del rendiment, seguit d’una breu explicació dels resultats després de cada optimització.Este proyecto se basa en adaptar y afinar los Mont-blanc benchmarks a la arquitectura multi-núcleo ARM 64 bits. Los Mont-Blanc benchmarks forman parte del proyecto Europeo Mont-Blanc y han sido desarrollados internamente en el BSC (Barcelona Supercomputing Center). Este proyecto explorará el potencial de usar la arquitectura ARM en un entorno HPC (High Performance Computing), esto incluye aprender a adaptar y afinar un programa paralelo, y analizar su comportamiento durante la ejecución. Como parte del proyecto, se analizará el rendimiento de cada benchmark usando herramientas de instrumentación como Extrae o Paraver. Cada benchmark será adaptado, afinado y ejecutado en los tres nuevos mini-clústeres de Mont-Blanc, Thunder (ARMv8 personalizado), Merlin (ARMv8 personalizado) y Jetson TX (ARMv8 cortex-a57) usando el modelo de programación OmpSs. Se mostrará la evolución del rendimiento obtenido, y una breve explicación de los resultados después de cada optimización

Sustainable Construction Engineering and Management

This Book is a Printed Edition of the Special Issue which covers sustainability as an emerging requirement in the fields of construction management, project management and engineering. We invited authors to submit their theoretical or experimental research articles that address the challenges and opportunities for sustainable construction in all its facets, including technical topics and specific operational or procedural solutions, as well as strategic approaches aimed at the project, company or industry level. Central to developments are smart technologies and sophisticated decision-making mechanisms that augment sustainable outcomes. The Special Issue was received with great interest by the research community and attracted a high number of submissions. The selection process sought to balance the inclusion of a broad representative spread of topics against research quality, with editors and reviewers settling on thirty-three articles for publication. The Editors invite all participating researchers and those interested in sustainable construction engineering and management to read the summary of the Special Issue and of course to access the full-text articles provided in the Book for deeper analyses

A model-based approach to System of Systems risk management

The failure of many System of Systems (SoS) enterprises can be attributed to the inappropriate application of traditional Systems Engineering (SE) processes within the SoS domain, because of the mistaken belief that a SoS can be regarded as a single large, or complex, system. SoS Engineering (SoSE) is a sub-discipline of SE; Risk Management and Modelling and Simulation (M&S) are key areas within SoSE, both of which also lie within the traditional SE domain. Risk Management of SoS requires a different approach to that currently taken for individual systems; if risk is managed for each component system then it cannot be assumed that the aggregated affect will be to mitigate risk at the SoS level. A literature review was undertaken examining three themes: (1) SoS Engineering (SoSE), (2) M&S and (3) Risk. Theme 1 of the literature provided insight into the activities comprising SoSE and its difference from traditional SE with risk management identified as a key activity. The second theme discussed the application of M&S to SoS, providing an output, which supported the identification of appropriate techniques and concluding that, the inherent complexity of a SoS required the use of M&S in order to support SoSE activities. Current risk management approaches were reviewed in theme 3 as well as the management of SoS risk. Although some specific examples of the management of SoS risk were found, no mature, general approach was identified, indicating a gap in current knowledge. However, it was noted most of these examples were underpinned by M&S approaches. It was therefore concluded a general approach SoS risk management utilising M&S methods would be of benefit. In order to fill the gap identified in current knowledge, this research proposed a new model based approach to Risk Management where risk identification was supported by a framework, which combined SoS system of interest dimensions with holistic risk types, where the resulting risks and contributing factors are captured in a causal network. Analysis of the causal network using a model technique selection tool, developed as part of this research, allowed the causal network to be simplified through the replacement of groups of elements within the network by appropriate supporting models. The Bayesian Belief Network (BBN) was identified as a suitable method to represent SoS risk. Supporting models run in Monte Carlo Simulations allowed data to be generated from which the risk BBNs could learn, thereby providing a more quantitative approach to SoS risk management. A method was developed which provided context to the BBN risk output through comparison with worst and best-case risk probabilities. The model based approach to Risk Management was applied to two very different case studies: Close Air Support mission planning and the Wheat Supply Chain, UK National Food Security risks, demonstrating its effectiveness and adaptability. The research established that the SoS SoI is essential for effective SoS risk identification and analysis of risk transfer, effective SoS modelling requires a range of techniques where suitability is determined by the problem context, the responsibility for SoS Risk Management is related to the overall SoS classification and the model based approach to SoS risk management was effective for both application case studies