Implementation and evaluation of a bony structure suppression software tool for chest X-ray imaging

Includes abstract.Includes bibliographical references.This project proposed to implement a bony structure suppression tool and analyse its effects on a texture-based classification algorithm in order to assist in the analysis of chest X-ray images. The diagnosis of pulmonary tuberculosis (TB) often includes the evaluation of chest X-ray images, and the reliability of image interpretation depends upon the experience of the radiologist. Computer-aided diagnosis (CAD) may be used to increase the accuracy of diagnosis. Overlapping structures in chest X-ray images hinder the ability of lung texture analysis for CAD to detect abnormalities. This dissertation examines whether the performance of texturebased CAD tools may be improved by the suppression of bony structures, particularly of the ribs, in the chest region

Statistical Shape Analysis for the Human Back

A thesis submitted to the department of Engineering and Technology in partial fulfilment of the requirements for the degree of Master of Philosophy in Production and Manufacturing Engineering at the University of WolverhamptonIn this research, Procrustes and Euclidean distance matrix analysis (EDMA) have been investigated for analysing the three-dimensional shape and form of the human back. Procrustes analysis is used to distinguish deformed backs from normal backs. EDMA is used to locate the changes occurring on the back surface due to spinal deformity (scoliosis, kyphosis and lordosis) for back deformity patients. A surface topography system, ISIS2 (Integrated Shape Imaging System 2), is available to measure the three-dimensional back surface. The system presents clinical parameters, which are based on distances and angles relative to certain anatomical landmarks on the back surface. Location, rotation and scale definitely influence these parameters. Although the anatomical landmarks are used in the present system to take some account of patient stance, it is still felt that variability in the clinical parameters is increased by the use of length and angle data. Patients also grow and so their back size, shape and form change between appointments with the doctor. Instead of distances and angles, geometric shape that is independent of location, rotation and scale effects could be measured. This research is mainly focusing on the geometric shape and form change in the back surface, thus removing the unwanted effects. Landmarks are used for describing back information and an analysis of the variability in positioning the landmarks has been carried out for repeated measurements. Generalized Procrustes analysis has been applied to all normal backs to calculate a mean Procrustes shape, which is named the standard normal shape (SNS). Each back (normal and deformed) is then translated, rotated and scaled to give a best fit with the SNS using ordinary Procrustes analysis. Riemannian distances are then estimated between the SNS and all individual backs. The highest Riemannian distance value between the normal backs and the SNS is lower than the lowest Riemannian distance value between the deformed backs and the SNS. The results shows that deformed backs can be differentiated from normal backs. EDMA has been used to estimate a mean form, variance-covariance matrix and mean form difference from all the normal backs. This mean form is named the standard normal form (SNF). The influence of individual landmarks for form difference between each deformed back and the SNF is estimated. A high value indicates high deformity on the location of that landmark and a low value close to 1 indicates less deformity. The result is displayed in a graph that provides information regarding the degree and location of the deformity. The novel aspects of this research lie in the development of an effective method for assessing the three-dimensional back shape; extracting automatic landmarks; visualizing back shape and back form differences

Locating regions of interest prior to X-ray imaging using stereo-photogrammetry

The research project aims at locating regions of interest (ROIs) on human subjects prior to X-ray imaging on the Lodox Statscan whole body imaging system

Computer-aided diagnosis of tuberculosis in paediatric chest X-rays using local textural analysis

Includes abstract.Includes bibliographical references (leaves 99-103).This report presents a computerised tool to analyse the appearance of the lung fields in paediatric chest X-rays to detect the presence of tuberculosis. The computer aided diagnosis (CAD) tool consists of 4 phases: 1) lung field segmentation; 2) lung field subdivision; 3) feature extraction and 4) classification. Lung field segmentation is performed using a semi-automatic implementation of the active shape model algorithm. Two approaches to subdividing the lung fields into regions of interest are compared. The first divides each lung field into 21 overlapping regions of varying sizes, resulting in a total of 42 regions per image; this approach is called the big region approach. The second approach divides the lung fields into a large number of overlapping circular regions of interest. The circular regions have a radius of 32 pixels and are placed on an 8 x 8 pixel grid. This approach is called the circular region approach. Textural features are extracted from each of the regions using the moments of responses to a multiscale bank of Gaussian filters. Additional positional features are added to the circular regions

Diseases of the Chest, Breast, Heart and Vessels 2019-2022

This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology

Diseases of the Chest, Breast, Heart and Vessels 2019-2022

This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology

Automated shape analysis and visualization of the human back.

Spinal and back deformities can lead to pain and discomfort, disrupting productivity, and may require prolonged treatment. The conventional method of assessing and monitoring tile de-formity using radiographs has known radiation hazards. An alternative approach for monitoring the deformity is to base the assessment on the shape of back surface. Though three-dimensional data acquisition methods exist, techniques to extract relevant information for clinical use have not been widely developed. Thi's thesis presentsthe content and progression of research into automated analysis and visu-alization of three-dimensional laser scans of the human back. Using mathematical shape analysis, methods have been developed to compute stable curvature of the back surface and to detect the anatomic landmarks from the curvature maps. Compared with manual palpation, the landmarks have been detected to within accuracy of 1.15mm and precision of 0.8111m.Based on the detected spinous process landmarks, the back midline which is the closest surface approximation of the spine, has been derived using constrained polynomial fitting and statistical techniques. Three-dimensional geometric measurementsbasedon the midline were then corn-puted to quantify the deformity. Visualization plays a crucial role in back shape analysis since it enables the exploration of back deformities without the need for physical manipulation of the subject. In the third phase,various visualization techniques have been developed, namely, continuous and discrete colour maps, contour maps and three-dimensional views. In the last phase of the research,a software system has been developed for automating the tasks involved in analysing, visualizing and quantifying of the back shape. The novel aspectsof this research lie in the development of effective noise smoothing methods for stable curvature computation; improved shape analysis and landmark detection algorithm; effective techniques for visualizing the shape of the back; derivation of the back midline using constrained polynomials and computation of three dimensional surface measurements.