Analysis and Detection of Pathological Voice using Glottal Source Features

Automatic detection of voice pathology enables objective assessment and earlier intervention for the diagnosis. This study provides a systematic analysis of glottal source features and investigates their effectiveness in voice pathology detection. Glottal source features are extracted using glottal flows estimated with the quasi-closed phase (QCP) glottal inverse filtering method, using approximate glottal source signals computed with the zero frequency filtering (ZFF) method, and using acoustic voice signals directly. In addition, we propose to derive mel-frequency cepstral coefficients (MFCCs) from the glottal source waveforms computed by QCP and ZFF to effectively capture the variations in glottal source spectra of pathological voice. Experiments were carried out using two databases, the Hospital Universitario Principe de Asturias (HUPA) database and the Saarbrucken Voice Disorders (SVD) database. Analysis of features revealed that the glottal source contains information that discriminates normal and pathological voice. Pathology detection experiments were carried out using support vector machine (SVM). From the detection experiments it was observed that the performance achieved with the studied glottal source features is comparable or better than that of conventional MFCCs and perceptual linear prediction (PLP) features. The best detection performance was achieved when the glottal source features were combined with the conventional MFCCs and PLP features, which indicates the complementary nature of the features

Detección automática de voz hipernasal de niños con labio y paladar hendido a partir de vocales y palabras del español usando medidas clásicas y análisis no lineal

RESUMEN: Este artículo presenta un sistema para la detección automática de señales de voz hipernasales basado en la combinación de dos diferentes esquemas de caracterización aplicados en las cinco vocales del español y dos palabras seleccionadas. El primer esquema está basado en características clásicas como perturbaciones del periodo fundamental, medidas de ruido y coeficientes cepstrales en la frecuencia de Mel. El segundo enfoque está basado en medidas de dinámica no lineal. Las características más relevantes son seleccionadas usando dos técnicas: análisis de componentes principales y selección flotante hacia adelante secuencial. La decisión acerca de si un registro de voz es hipernasal o sano es tomada usando una máquina de soporte vectorial de margen suave. Los experimentos consideran grabaciones de las cinco vocales del idioma español y las palabras y se consideran, asimismo, tres conjuntos de características: (1) el enfoque clásico, (2) el análisis de dinámica no lineal y (3) la combinación de ambos esquemas. En general, los aciertos son mayores y más estables cuando las características clásicas y no lineales son combinadas, indicando que el análisis de dinámica no lineal se complementa con el esquema clásico.ABSTRACT: This paper presents a system for the automatic detection of hypernasal speech signals based on the combination of two different characterization approaches applied to the five spanish vowels and two selected words. The first approach is based on classical features such as pitch period perturbations, noise measures, and Mel-Frequency Cepstral Coefficients (MFCC). The second approach is based on the Non-Linear Dynamics (NLD) analysis. The most relevant features are selected and sorted using two techniques: Principal Components Analysis (PCA) and Sequential Forward Floating Selection (SFFS). The decision about whether a voice record is hypernasal or healthy is taken using a Soft Margin - Support Vector Machine (SM-SVM). Experiments upon recordings of the five Spanish vowels and the words are performed considering three different set of features: (1) the classical approach, (2) the NLD analysis, and (3) the combination of the classical and NLD measures. In general, the accuracies are higher and more stable when the classical and NLD features are combined, indicating that the NLD analysis is complementary to the classical approach

Introducing non-linear analysis into sustained speech characterization to improve sleep apnea detection

The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-25020-0_28Proceedings of 5th International Conference on Nonlinear Speech Processing, NOLISP 2011, Las Palmas de Gran Canaria (Spain)We present a novel approach for detecting severe obstructive sleep apnea (OSA) cases by introducing non-linear analysis into sustained speech characterization. The proposed scheme was designed for providing additional information into our baseline system, built on top of state-of-the-art cepstral domain modeling techniques, aiming to improve accuracy rates. This new information is lightly correlated with our previous MFCC modeling of sustained speech and uncorrelated with the information in our continuous speech modeling scheme. Tests have been performed to evaluate the improvement for our detection task, based on sustained speech as well as combined with a continuous speech classifier, resulting in a 10% relative reduction in classification for the first and a 33% relative reduction for the fused scheme. Results encourage us to consider the existence of non-linear effects on OSA patients’ voices, and to think about tools which could be used to improve short-time analysis.The activities described in this paper were funded by the Spanish Ministry of Science and Innovation as part of the TEC2009-14719-C02-02 (PriorSpeech) project

Introducing non-linear analysis into sustained speech characterization to improve sleep apnea detection

We present a novel approach for detecting severe obstructive sleep apnea (OSA) cases by introducing non-linear analysis into sustained speech characterization. The proposed scheme was designed for providing additional information into our baseline system, built on top of state-of-the-art cepstral domain modeling techniques, aiming to improve accuracy rates. This new information is lightly correlated with our previous MFCC modeling of sustained speech and uncorrelated with the information in our continuous speech modeling scheme. Tests have been performed to evaluate the improvement for our detection task, based on sustained speech as well as combined with a continuous speech classifier, resulting in a 10% relative reduction in classification for the first and a 33% relative reduction for the fused scheme. Results encourage us to consider the existence of non-linear effects on OSA patients' voices, and to think about tools which could be used to improve short-time analysis

Low band spectral tilt analysis for pathological voice discrimination

This paper presents a new method for discriminating between subjects with healthy voices and subjects with diseases in the vocal folds. This method uses speech signals and spectral analysis of the sustained vowel /a/. The slope between a first band of the signal defined in the first two harmonics and a second band defined in the zone of the /a/ first formant contains information that allows to correctly classify the database of pathological voices of the University of Sao Paulo. The presented method can be applied in the direct analysis of spectra or implemented in high-level classifiers as a complement to other parameters.info:eu-repo/semantics/publishedVersio

GMM-based classifiers for the automatic detection of obstructive sleep apnea

The aim of automatic pathological voice detection systems is to serve as tools, to medical specialists, for a more objective, less invasive and improved diagnosis of diseases. In this respect, the gold standard for those system include the usage of a optimized representation of the spectral envelope, either based on cepstral coefficients from the mel-scaled Fourier spectral envelope (Mel-Frequency Cepstral Coefficients) or from an all-pole estimation (Linear Prediction Coding Cepstral Coefficients) forcharacterization, and Gaussian Mixture Models for posterior classification. However, the study of recently proposed GMM-based classifiers as well as Nuisance mitigation techniques, such as those employed in speaker recognition, has not been widely considered inpathology detection labours. The present work aims at testing whether or not the employment of such speaker recognition tools might contribute to improve system performance in pathology detection systems, specifically in the automatic detection of Obstructive Sleep Apnea. The testing procedure employs an Obstructive Sleep Apnea database, in conjunction with GMM-based classifiers looking for a better performance. The results show that an improved performance might be obtained by using such approach

Models and analysis of vocal emissions for biomedical applications: 5th International Workshop: December 13-15, 2007, Firenze, Italy

The MAVEBA Workshop proceedings, held on a biannual basis, collect the scientific papers presented both as oral and poster contributions, during the conference. The main subjects are: development of theoretical and mechanical models as an aid to the study of main phonatory dysfunctions, as well as the biomedical engineering methods for the analysis of voice signals and images, as a support to clinical diagnosis and classification of vocal pathologies. The Workshop has the sponsorship of: Ente Cassa Risparmio di Firenze, COST Action 2103, Biomedical Signal Processing and Control Journal (Elsevier Eds.), IEEE Biomedical Engineering Soc. Special Issues of International Journals have been, and will be, published, collecting selected papers from the conference