A gaussian mixture-based approach to synthesizing nonlinear feature functions for automated object detection

Feature design is an important part to identify objects of interest into a known number of categories or classes in object detection. Based on the depth-first search for higher order feature functions, the technique of automated feature synthesis is generally considered to be a process of creating more effective features from raw feature data during the run of the algorithms. This dynamic synthesis of nonlinear feature functions is a challenging problem in object detection. This thesis presents a combinatorial approach of genetic programming and the expectation maximization algorithm (GP-EM) to synthesize nonlinear feature functions automatically in order to solve the given tasks of object detection. The EM algorithm investigates the use of Gaussian mixture which is able to model the behaviour of the training samples during an optimal GP search strategy. Based on the Gaussian probability assumption, the GP-EM method is capable of performing simultaneously dynamic feature synthesis and model-based generalization. The EM part of the approach leads to the application of the maximum likelihood (ML) operation that provides protection against inter-cluster data separation and thus exhibits improved convergence. Additionally, with the GP-EM method, an innovative technique, called the histogram region of interest by thresholds (HROIBT), is introduced for diagnosing protein conformation defects (PCD) from microscopic imagery. The experimental results show that the proposed approach improves the detection accuracy and efficiency of pattern object discovery, as compared to single GP-based feature synthesis methods and also a number of other object detection systems. The GP-EM method projects the hyperspace of the raw data onto lower-dimensional spaces efficiently, resulting in faster computational classification processes

Designing algorithms to aid discovery by chemical robots

Recently, automated robotic systems have become very efficient, thanks to improved coupling between sensor systems and algorithms, of which the latter have been gaining significance thanks to the increase in computing power over the past few decades. However, intelligent automated chemistry platforms for discovery orientated tasks need to be able to cope with the unknown, which is a profoundly hard problem. In this Outlook, we describe how recent advances in the design and application of algorithms, coupled with the increased amount of chemical data available, and automation and control systems may allow more productive chemical research and the development of chemical robots able to target discovery. This is shown through examples of workflow and data processing with automation and control, and through the use of both well-used and cutting-edge algorithms illustrated using recent studies in chemistry. Finally, several algorithms are presented in relation to chemical robots and chemical intelligence for knowledge discovery

CryptoKnight:generating and modelling compiled cryptographic primitives

Cryptovirological augmentations present an immediate, incomparable threat. Over the last decade, the substantial proliferation of crypto-ransomware has had widespread consequences for consumers and organisations alike. Established preventive measures perform well, however, the problem has not ceased. Reverse engineering potentially malicious software is a cumbersome task due to platform eccentricities and obfuscated transmutation mechanisms, hence requiring smarter, more efficient detection strategies. The following manuscript presents a novel approach for the classification of cryptographic primitives in compiled binary executables using deep learning. The model blueprint, a Dynamic Convolutional Neural Network (DCNN), is fittingly configured to learn from variable-length control flow diagnostics output from a dynamic trace. To rival the size and variability of equivalent datasets, and to adequately train our model without risking adverse exposure, a methodology for the procedural generation of synthetic cryptographic binaries is defined, using core primitives from OpenSSL with multivariate obfuscation, to draw a vastly scalable distribution. The library, CryptoKnight, rendered an algorithmic pool of AES, RC4, Blowfish, MD5 and RSA to synthesise combinable variants which automatically fed into its core model. Converging at 96% accuracy, CryptoKnight was successfully able to classify the sample pool with minimal loss and correctly identified the algorithm in a real-world crypto-ransomware applicatio

MedGAN: Medical Image Translation using GANs

Image-to-image translation is considered a new frontier in the field of medical image analysis, with numerous potential applications. However, a large portion of recent approaches offers individualized solutions based on specialized task-specific architectures or require refinement through non-end-to-end training. In this paper, we propose a new framework, named MedGAN, for medical image-to-image translation which operates on the image level in an end-to-end manner. MedGAN builds upon recent advances in the field of generative adversarial networks (GANs) by merging the adversarial framework with a new combination of non-adversarial losses. We utilize a discriminator network as a trainable feature extractor which penalizes the discrepancy between the translated medical images and the desired modalities. Moreover, style-transfer losses are utilized to match the textures and fine-structures of the desired target images to the translated images. Additionally, we present a new generator architecture, titled CasNet, which enhances the sharpness of the translated medical outputs through progressive refinement via encoder-decoder pairs. Without any application-specific modifications, we apply MedGAN on three different tasks: PET-CT translation, correction of MR motion artefacts and PET image denoising. Perceptual analysis by radiologists and quantitative evaluations illustrate that the MedGAN outperforms other existing translation approaches.Comment: 16 pages, 8 figure