1,580 research outputs found

    An active-architecture approach to COTS integration

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    Commercial off-the-shelf (COTS) software products are increasingly used as standard components within integrated information systems. This creates challenges since both their developers and source code are not usually available, and the ongoing development of COTS cannot be predicted. The ArchWare Framework approach recognises COTS products as part of the ambient environment of an information system and therefore an important part of development is incorporating COTS as effective system components. This integration of COTS components, and the composition of components, is captured by an active architecture model which changes as the system evolves. Indeed the architecture modelling language used enables it to express the monitoring and evolution of a system. This active architecture model is structured using control system principles. By modelling both integration and evolution it can guide the system’s response to both predicted and emergent changes that arise from the use of COTS products.Publisher PDFPeer reviewe

    EXPLOITING KASPAROV'S LAW: ENHANCED INFORMATION SYSTEMS INTEGRATION IN DOD SIMULATION-BASED TRAINING ENVIRONMENTS

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    Despite recent advances in the representation of logistics considerations in DOD staff training and wargaming simulations, logistics information systems (IS) remain underrepresented. Unlike many command and control (C2) systems, which can be integrated with simulations through common protocols (e.g., OTH-Gold), many logistics ISs require manpower-intensive human-in-the-loop (HitL) processes for simulation-IS (sim-IS) integration. Where automated sim-IS integration has been achieved, it often does not simulate important sociotechnical system (STS) dynamics, such as information latency and human error, presenting decision-makers with an unrealistic representation of logistics C2 capabilities in context. This research seeks to overcome the limitations of conventional sim-IS interoperability approaches by developing and validating a new approach for sim-IS information exchange through robotic process automation (RPA). RPA software supports the automation of IS information exchange through ISs’ existing graphical user interfaces. This “outside-in” approach to IS integration mitigates the need for engineering changes in ISs (or simulations) for automated information exchange. In addition to validating the potential for an RPA-based approach to sim-IS integration, this research presents recommendations for a Distributed Simulation Engineering and Execution Process (DSEEP) overlay to guide the engineering and execution of sim-IS environments.Major, United States Marine CorpsApproved for public release. Distribution is unlimited

    A Coevolutionary View of Information Services Development: Lessons from the U.S. National Oceanic and Atmospheric Administration

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    This study investigates the process of information services development based on a case study of the experience of the U.S. National Oceanic and Atmospheric Administration (NOAA). In this study, we develop theoretical constructs that can inform researchers and practitioners on (1) what the critical domains and interactions associated with the emerging process of information service development at these organizations were, and (2) how information services at NOAA evolved over time? Adopting a coevolutionary view, we identified distinct yet interdependent domains that affected, and were affected by, the information services development process; these were: (1) services choreography, through which service interactions and collaborations are managed; (2) services orchestration, through which service processes are selected and interact; and (3) services instrumentation, by which services are developed and architected. Using the coevolutionary view, we uncovered three adaptive principles that explain the interplay among domains and interactions over time: adaptive tensions, requisite variety, and modular design. We discuss our findings’ implications for research and practice and offer propositions for future research

    Sequence- and structure-based approaches to deciphering enzyme evolution in the Haloalkonoate Dehalogenase superfamily

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    Understanding how changes in functional requirements of the cell select for changes in protein sequence and structure is a fundamental challenge in molecular evolution. This dissertation delineates some of the underlying evolutionary forces using as a model system, the Haloalkanoate Dehalogenase Superfamily (HADSF). HADSF members have unique cap-core architecture with the Rossmann-fold core domain accessorized by variable cap domain insertions (delineated by length, topology, and point of insertion). To identify the boundaries of variable domain insertions in protein sequences, I have developed a comprehensive computational strategy (CapPredictor or CP) using a novel sequence alignment algorithm in conjunction with a structure-guided sequence profile. Analysis of more than 40,000 HADSF sequences led to the following observations: (i) cap-type classes exhibit similar distributions across different phyla, indicating existence of all cap-types in the last universal common ancestor, and (ii) comparative analysis of the predicted cap-type and functional diversity indicated that cap-type does not dictate the divergence of substrate recognition and chemical pathway, and hence biological function. By analyzing a unique dataset of core- and cap-domain-only protein structures, I investigated the consequences of the accessory cap domain on the sequence-structure relationship of the core domain. The relationship between sequence and structure divergence in the core fold was shown to be monotonic and independent of the corresponding cap type. However, core domains with the same cap type bore a greater similarity than the core domains with different cap types, suggesting coevolution of the cap and core domains. Remarkably, a few degrees of freedom are needed to describe the structural diversity in the Rossmann fold accounting for the majority of the observed structural variance. Finally, I examined the location and role of conserved residue positions and co-evolving residue pairs in the core domain in the context of the cap domain. Positions critical for function were conserved while non-conserved positions mapped to highly mobile regions. Notably, we found exponential dependence of co-variance on inter-residue distance. Collectively, these novel algorithms and analyses contribute to an improved understanding of enzyme evolution, especially in the context of the use of domain insertions to expand substrate specificity and chemical mechanism
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