Vitamin D as One of Predicators of the Stable Viral Response to Antiviral Therapy in Patients with Chronis Hepatitis С

Chronic hepatitis C (CHC) it is not exceptionally medical problem but a significant social and economic threat, taking into account the unfavorable consequences of this disease: cirrhosis and hepatocellular carcinoma. And as a result - the high level of disability. In the article are presented the results of examination of 41 patients with chronic hepatitis C, with 1 genotype, who received the antiviral therapy (AVT). All patients underwent determination of the level of 5-hydroxycholeсalсeferol (25-OH vit D3), vitamin D and also the study of IL-28B polymorphism as the one of predicators of response to AVT. It was demonstrated, that in patients with hepatitis was observed the deficit of 25-OH vit D3 and general vitamin D. It was established, that in patients with the normal 25-OH vit D3 level SVR (stable viral response) was observed in 1,4 times more often than in patients with deficit of 25-OH vit D3. That is the level of 25-OH vit D3 can be considered as a predicator of SVR to AVT

The city as one thing

This paper summarises the latest theories in the field of space syntax. It opens with a discussion of the relationship between the form of urban grids and the process of how cities are formed by human activity; this is done by a comprehensive review of space syntax theory from its starting point in the1970s. The paper goes on to present research into how cities balance the micro-economic factors which shape the spatial structure of cities with the cultural factors that shape the underlying form of residential areas. It goes on to discuss the relationship between activity and space and how this relationship is formed by the way different activities make different demands on movement and co-presence. The paper ends with a discussion regarding the manner in which patterns of spatial integration influence the location of different classes and social groups in the city and contribute to the pathology of housing estates. The paper concludes that spatial form needs to be understood as a contributing factor in forming the patterns of integration and segregation in cities

The People as One Malala

Third Plac

Laplacian growth as one-dimensional turbulence

A new model of Laplacian stochastic growth is formulated using conformal mappings. The model describes two growth regimes, stable and turbulent, separated by a sharp phase transition. The first few Fourier components of the mapping define the web, an envelope of the cluster. The web is used to study the transition and the dynamics of large-scale features of the cluster characterized by evolution from macro- to micro-scales. Also, we derive scaling laws for the cluster size.Comment: 4 pages, RevTex, 4 figure