3,212 research outputs found
Cardiovascular/Stroke Risk Assessment in Patients with Erectile DysfunctionâA Role of Carotid Wall Arterial Imaging and Plaque Tissue Characterization Using Artificial Intelligence Paradigm: A Narrative Review
Purpose: The role of erectile dysfunction (ED) has recently shown an association with the risk of stroke and coronary heart disease (CHD) via the atherosclerotic pathway. Cardiovascular disease (CVD)/stroke risk has been widely understood with the help of carotid artery disease (CTAD), a surrogate biomarker for CHD. The proposed study emphasizes artificial intelligence-based frameworks such as machine learning (ML) and deep learning (DL) that can accurately predict the severity of CVD/stroke risk using carotid wall arterial imaging in ED patients. Methods: Using the PRISMA model, 231 of the best studies were selected. The proposed study mainly consists of two components: (i) the pathophysiology of ED and its link with coronary artery disease (COAD) and CHD in the ED framework and (ii) the ultrasonic-image morphological changes in the carotid arterial walls by quantifying the wall parameters and the characterization of the wall tissue by adapting the ML/DL-based methods, both for the prediction of the severity of CVD risk. The proposed study analyzes the hypothesis that ML/DL can lead to an accurate and early diagnosis of the CVD/stroke risk in ED patients. Our finding suggests that the routine ED patient practice can be amended for ML/DL-based CVD/stroke risk assessment using carotid wall arterial imaging leading to fast, reliable, and accurate CVD/stroke risk stratification. Summary: We conclude that ML and DL methods are very powerful tools for the characterization of CVD/stroke in patients with varying ED conditions. We anticipate a rapid growth of these tools for early and better CVD/stroke risk management in ED patients
Machine learning techniques for arrhythmic risk stratification: a review of the literature
Ventricular arrhythmias (VAs) and sudden cardiac death (SCD) are significant adverse events that affect the morbidity and mortality of both the general population and patients with predisposing cardiovascular risk factors. Currently, conventional disease-specific scores are used for risk stratification purposes. However, these risk scores have several limitations, including variations among validation cohorts, the inclusion of a limited number of predictors while omitting important variables, as well as hidden relationships between predictors. Machine learning (ML) techniques are based on algorithms that describe intervariable relationships. Recent studies have implemented ML techniques to construct models for the prediction of fatal VAs. However, the application of ML study findings is limited by the absence of established frameworks for its implementation, in addition to cliniciansâ unfamiliarity with ML techniques. This review, therefore, aims to provide an accessible and easy-to-understand summary of the existing evidence about the use of ML techniques in the prediction of VAs. Our findings suggest that ML algorithms improve arrhythmic prediction performance in different clinical settings. However, it should be emphasized that prospective studies comparing ML algorithms to conventional risk models are needed while a regulatory framework is required prior to their implementation in clinical practice
Deep Learning Paradigm for Cardiovascular Disease/Stroke Risk Stratification in Parkinsonâs Disease Affected by COVIDâ19: A Narrative Review
Background and Motivation: Parkinsonâs disease (PD) is one of the most serious, non-curable, and expensive to treat. Recently, machine learning (ML) has shown to be able to predict cardiovascular/stroke risk in PD patients. The presence of COVIDâ19 causes the ML systems to be-come severely nonâlinear and poses challenges in cardiovascular/stroke risk stratification. Further, due to comorbidity, sample size constraints, and poor scientific and clinical validation techniques, there have been no wellâexplained ML paradigms. Deep neural networks are powerful learning machines that generalize nonâlinear conditions. This study presents a novel investigation of deep learning (DL) solutions for CVD/stroke risk prediction in PD patients affected by the COVIDâ19 framework. Method: The PRISMA search strategy was used for the selection of 292 studies closely associated with the effect of PD on CVD risk in the COVIDâ19 framework. We study the hypothesis that PD in the presence of COVIDâ19 can cause more harm to the heart and brain than in nonâ COVIDâ19 conditions. COVIDâ19 lung damage severity can be used as a covariate during DL training model designs. We, therefore, propose a DL model for the estimation of, (i) COVIDâ19 lesions in computed tomography (CT) scans and (ii) combining the covariates of PD, COVIDâ19 lesions, office and laboratory arterial atherosclerotic imageâbased biomarkers, and medicine usage for the PD patients for the design of DL pointâbased models for CVD/stroke risk stratification. Results: We validated the feasibility of CVD/stroke risk stratification in PD patients in the presence of a COVIDâ 19 environment and this was also verified. DL architectures like long shortâterm memory (LSTM), and recurrent neural network (RNN) were studied for CVD/stroke risk stratification showing powerful designs. Lastly, we examined the artificial intelligence bias and provided recommendations for early detection of CVD/stroke in PD patients in the presence of COVIDâ19. Conclusion: The DL is a very powerful tool for predicting CVD/stroke risk in PD patients affected by COVIDâ19
Artificial Intelligence in Assessing Cardiovascular Diseases and Risk Factors via Retinal Fundus Images: A Review of the Last Decade
Background: Cardiovascular diseases (CVDs) continue to be the leading cause
of mortality on a global scale. In recent years, the application of artificial
intelligence (AI) techniques, particularly deep learning (DL), has gained
considerable popularity for evaluating the various aspects of CVDs. Moreover,
using fundus images and optical coherence tomography angiography (OCTA) to
diagnose retinal diseases has been extensively studied. To better understand
heart function and anticipate changes based on microvascular characteristics
and function, researchers are currently exploring the integration of AI with
non-invasive retinal scanning. Leveraging AI-assisted early detection and
prediction of cardiovascular diseases on a large scale holds excellent
potential to mitigate cardiovascular events and alleviate the economic burden
on healthcare systems. Method: A comprehensive search was conducted across
various databases, including PubMed, Medline, Google Scholar, Scopus, Web of
Sciences, IEEE Xplore, and ACM Digital Library, using specific keywords related
to cardiovascular diseases and artificial intelligence. Results: A total of 87
English-language publications, selected for relevance were included in the
study, and additional references were considered. This study presents an
overview of the current advancements and challenges in employing retinal
imaging and artificial intelligence to identify cardiovascular disorders and
provides insights for further exploration in this field. Conclusion:
Researchers aim to develop precise disease prognosis patterns as the aging
population and global CVD burden increase. AI and deep learning are
transforming healthcare, offering the potential for single retinal image-based
diagnosis of various CVDs, albeit with the need for accelerated adoption in
healthcare systems.Comment: 40 pages, 5 figures, 2 tables, 91 reference
Deep Learning Paradigm for Cardiovascular Disease/Stroke Risk Stratification in Parkinsonâs Disease Affected by COVIDâ19: A Narrative Review
Background and Motivation: Parkinsonâs disease (PD) is one of the most serious, non-curable, and expensive to treat. Recently, machine learning (ML) has shown to be able to predict cardiovascular/stroke risk in PD patients. The presence of COVIDâ19 causes the ML systems to be-come severely nonâlinear and poses challenges in cardiovascular/stroke risk stratification. Further, due to comorbidity, sample size constraints, and poor scientific and clinical validation techniques, there have been no wellâexplained ML paradigms. Deep neural networks are powerful learning machines that generalize nonâlinear conditions. This study presents a novel investigation of deep learning (DL) solutions for CVD/stroke risk prediction in PD patients affected by the COVIDâ19 framework. Method: The PRISMA search strategy was used for the selection of 292 studies closely associated with the effect of PD on CVD risk in the COVIDâ19 framework. We study the hypothesis that PD in the presence of COVIDâ19 can cause more harm to the heart and brain than in nonâ COVIDâ19 conditions. COVIDâ19 lung damage severity can be used as a covariate during DL training model designs. We, therefore, propose a DL model for the estimation of, (i) COVIDâ19 lesions in computed tomography (CT) scans and (ii) combining the covariates of PD, COVIDâ19 lesions, office and laboratory arterial atherosclerotic imageâbased biomarkers, and medicine usage for the PD patients for the design of DL pointâbased models for CVD/stroke risk stratification. Results: We validated the feasibility of CVD/stroke risk stratification in PD patients in the presence of a COVIDâ 19 environment and this was also verified. DL architectures like long shortâterm memory (LSTM), and recurrent neural network (RNN) were studied for CVD/stroke risk stratification showing powerful designs. Lastly, we examined the artificial intelligence bias and provided recommendations for early detection of CVD/stroke in PD patients in the presence of COVIDâ19. Conclusion: The DL is a very powerful tool for predicting CVD/stroke risk in PD patients affected by COVIDâ19. © 2022 by the authors. Licensee MDPI, Basel, Switzerland
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