363 research outputs found
Demonstration of Semantic Web-based Medical Ontologies and Clinical Decision Support Systems
Master's thesis in Information- and communication technology IKT590 - University of Agder 2016Konfidensiell til / confidential until 01.01.202
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Grid-based semantic integration of heterogeneous data resources: Implementation on a HealthGrid
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.The semantic integration of geographically distributed and heterogeneous data
resources still remains a key challenge in Grid infrastructures. Today's
mainstream Grid technologies hold the promise to meet this challenge in a
systematic manner, making data applications more scalable and manageable. The
thesis conducts a thorough investigation of the problem, the state of the art, and
the related technologies, and proposes an Architecture for Semantic Integration of
Data Sources (ASIDS) addressing the semantic heterogeneity issue. It defines a
simple mechanism for the interoperability of heterogeneous data sources in order
to extract or discover information regardless of their different semantics. The
constituent technologies of this architecture include Globus Toolkit (GT4) and
OGSA-DAI (Open Grid Service Architecture Data Integration and Access)
alongside other web services technologies such as XML (Extensive Markup
Language). To show this, the ASIDS architecture was implemented and tested in a
realistic setting by building an exemplar application prototype on a HealthGrid
(pilot implementation).
The study followed an empirical research methodology and was informed by
extensive literature surveys and a critical analysis of the relevant technologies and
their synergies. The two literature reviews, together with the analysis of the
technology background, have provided a good overview of the current Grid and
HealthGrid landscape, produced some valuable taxonomies, explored new paths
by integrating technologies, and more importantly illuminated the problem and
guided the research process towards a promising solution. Yet the primary
contribution of this research is an approach that uses contemporary Grid
technologies for integrating heterogeneous data resources that have semantically
different. data fields (attributes). It has been practically demonstrated (using a
prototype HealthGrid) that discovery in semantically integrated distributed data
sources can be feasible by using mainstream Grid technologies, which have been
shown to have some Significant advantages over non-Grid based approaches
Transformation of Health and Social Care Systems—An Interdisciplinary Approach Toward a Foundational Architecture
Objective:
For realizing pervasive and ubiquitous health and social care services in a safe and high quality as well as efficient and effective way, health and social care systems have to meet new organizational, methodological, and technological paradigms. The resulting ecosystems are highly complex, highly distributed, and highly dynamic, following inter-organizational and even international approaches. Even though based on international, but domain-specific models and standards, achieving interoperability between such systems integrating multiple domains managed by multiple disciplines and their individually skilled actors is cumbersome.
Methods:
Using the abstract presentation of any system by the universal type theory as well as universal logics and combining the resulting Barendregt Cube with parameters and the engineering approach of cognitive theories, systems theory, and good modeling best practices, this study argues for a generic reference architecture model moderating between the different perspectives and disciplines involved provide on that system. To represent architectural elements consistently, an aligned system of ontologies is used.
Results:
The system-oriented, architecture-centric, and ontology-based generic reference model allows for re-engineering the existing and emerging knowledge representations, models, and standards, also considering the real-world business processes and the related development process of supporting IT systems for the sake of comprehensive systems integration and interoperability. The solution enables the analysis, design, and implementation of dynamic, interoperable multi-domain systems without requesting continuous revision of existing specifications
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