A simple polynomial time algorithm to approximate the permanent within a simply exponential factor

We present a simple randomized polynomial time algorithm to approximate the mixed discriminant of $n$ positive semidefinite $n \times n$ matrices within a factor $2^{O(n)}$. Consequently, the algorithm allows us to approximate in randomized polynomial time the permanent of a given $n \times n$ non-negative matrix within a factor $2^{O(n)}$. When applied to approximating the permanent, the algorithm turns out to be a simple modification of the well-known Godsil-Gutman estimator

Exploiting bounded signal flow for graph orientation based on cause-effect pairs

Background: We consider the following problem: Given an undirected network and a set of sender–receiver pairs, direct all edges such that the maximum number of “signal flows ” defined by the pairs can be routed respecting edge directions. This problem has applications in understanding protein interaction based cell regulation mechanisms. Since this problem is NP-hard, research so far concentrated on polynomial-time approximation algorithms and tractable special cases. Results: We take the viewpoint of parameterized algorithmics and examine several parameters related to the maximum signal flow over vertices or edges. We provide several fixed-parameter tractability results, and in one case a sharp complexity dichotomy between a linear-time solvable case and a slightly more general NP-hard case. We examine the value of these parameters for several real-world network instances. Conclusions: Several biologically relevant special cases of the NP-hard problem can be solved to optimality. In this way, parameterized analysis yields both deeper insight into the computational complexity and practical solving strategies. Background Current technologies [1] like two-hybrid screening ca

Virtual Network Embedding Approximations: Leveraging Randomized Rounding

© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.The Virtual Network Embedding Problem (VNEP) captures the essence of many resource allocation problems. In the VNEP, customers request resources in the form of Virtual Networks. An embedding of a virtual network on a shared physical infrastructure is the joint mapping of (virtual) nodes to physical servers together with the mapping of (virtual) edges onto paths in the physical network connecting the respective servers. This work initiates the study of approximation algorithms for the VNEP for general request graphs. Concretely, we study the offline setting with admission control: given multiple requests, the task is to embed the most profitable subset while not exceeding resource capacities. Our approximation is based on the randomized rounding of Linear Programming (LP) solutions. Interestingly, we uncover that the standard LP formulation for the VNEP exhibits an inherent structural deficit when considering general virtual network topologies: its solutions cannot be decomposed into valid embeddings. In turn, focusing on the class of cactus request graphs, we devise a novel LP formulation, whose solutions can be decomposed. Proving performance guarantees of our rounding scheme, we obtain the first approximation algorithm for the VNEP in the resource augmentation model. We propose different types of rounding heuristics and evaluate their performance in an extensive computational study. Our results indicate that good solutions can be achieved even without resource augmentations. Specifically, heuristical rounding achieves 77.2% of the baseline’s profit on average while respecting capacities.BMBF, 01IS12056, Software Campus GrantEC/H2020/679158/EU/Resolving the Tussle in the Internet: Mapping, Architecture, and Policy Making/ResolutioNe

Counting and Sampling from Markov Equivalent DAGs Using Clique Trees

A directed acyclic graph (DAG) is the most common graphical model for representing causal relationships among a set of variables. When restricted to using only observational data, the structure of the ground truth DAG is identifiable only up to Markov equivalence, based on conditional independence relations among the variables. Therefore, the number of DAGs equivalent to the ground truth DAG is an indicator of the causal complexity of the underlying structure--roughly speaking, it shows how many interventions or how much additional information is further needed to recover the underlying DAG. In this paper, we propose a new technique for counting the number of DAGs in a Markov equivalence class. Our approach is based on the clique tree representation of chordal graphs. We show that in the case of bounded degree graphs, the proposed algorithm is polynomial time. We further demonstrate that this technique can be utilized for uniform sampling from a Markov equivalence class, which provides a stochastic way to enumerate DAGs in the equivalence class and may be needed for finding the best DAG or for causal inference given the equivalence class as input. We also extend our counting and sampling method to the case where prior knowledge about the underlying DAG is available, and present applications of this extension in causal experiment design and estimating the causal effect of joint interventions