Multiple Retrieval Models and Regression Models for Prior Art Search

This paper presents the system called PATATRAS (PATent and Article Tracking, Retrieval and AnalysiS) realized for the IP track of CLEF 2009. Our approach presents three main characteristics: 1. The usage of multiple retrieval models (KL, Okapi) and term index definitions (lemma, phrase, concept) for the three languages considered in the present track (English, French, German) producing ten different sets of ranked results. 2. The merging of the different results based on multiple regression models using an additional validation set created from the patent collection. 3. The exploitation of patent metadata and of the citation structures for creating restricted initial working sets of patents and for producing a final re-ranking regression model. As we exploit specific metadata of the patent documents and the citation relations only at the creation of initial working sets and during the final post ranking step, our architecture remains generic and easy to extend

Biomedical information extraction for matching patients to clinical trials

Digital Medical information had an astonishing growth on the last decades, driven by an unprecedented number of medical writers, which lead to a complete revolution in what and how much information is available to the health professionals. The problem with this wave of information is that performing a precise selection of the information retrieved by medical information repositories is very exhaustive and time consuming for physicians. This is one of the biggest challenges for physicians with the new digital era: how to reduce the time spent finding the perfect matching document for a patient (e.g. intervention articles, clinical trial, prescriptions). Precision Medicine (PM) 2017 is the track by the Text REtrieval Conference (TREC), that is focused on this type of challenges exclusively for oncology. Using a dataset with a large amount of clinical trials, this track is a good real life example on how information retrieval solutions can be used to solve this types of problems. This track can be a very good starting point for applying information extraction and retrieval methods, in a very complex domain. The purpose of this thesis is to improve a system designed by the NovaSearch team for TREC PM 2017 Clinical Trials task, which got ranked on the top-5 systems of 2017. The NovaSearch team also participated on the 2018 track and got a 15% increase on precision compared to the 2017 one. It was used multiple IR techniques for information extraction and processing of data, including rank fusion, query expansion (e.g. Pseudo relevance feedback, Mesh terms expansion) and experiments with Learning to Rank (LETOR) algorithms. Our goal is to retrieve the best possible set of trials for a given patient, using precise documents filters to exclude the unwanted clinical trials. This work can open doors in what can be done for searching and perceiving the criteria to exclude or include the trials, helping physicians even on the more complex and difficult information retrieval tasks

Language modeling approaches to question answering

In today’s environment of information overload, Question Answering (QA) is a critically important research area. QA is the task of automatically extracting a precise answer from one or more data sources to a question posed in natural language. A twostage strategy is typically adopted when designing a QA system; the first stage is an Information Retrieval (IR) process which returns a set of candidate documents relevant to the question and the second stage narrows the information contained in those passages down to a single response (sentence or entity) that answers the question, typically using Information Extraction (IE) or Natural Language Processing methods. This research proposes novel techniques for QA by enhancing the user’s original query with latent semantic information from the corpus. This enhanced query is then applied to both the first and second stages of the QA architecture. To build the enhanced query, we propose the Aspect-Based Relevance Language Model as an approach that uses statistical language modeling techniques to measure the likelihood of relevance of a concept (oraspect as defined by Probabilistic Latent Semantic Analysis) to a question. We then use terms from the aspects that have the highest likelihood of relevance to design a model for a semantic Question Context, which includes sense-disambiguated terms than amplify the user’s query. Question Context is incorporated into the first state of QA as query expansion to improve recall. We then derive a novel measure called Answer Credibility from the Question Context. Answer Credibility may be thought of as a statistical measure of the reliability of a candidate answer with respect to a question and the source text from which the candidate answer was derived. We incorporate Answer Credibility in the Answer Validation process; the answer with the highest score after the application of Answer Credibility is returned to the user. Our techniques show performance improvements over state-of-the-art approaches, and have the advantage that they use statistical techniques to derive semantic information to aid the process of QA.Ph.D., Information Science and Technology -- Drexel University, 200