Spatial-temporal data modelling and processing for personalised decision support

The purpose of this research is to undertake the modelling of dynamic data without losing any of the temporal relationships, and to be able to predict likelihood of outcome as far in advance of actual occurrence as possible. To this end a novel computational architecture for personalised ( individualised) modelling of spatio-temporal data based on spiking neural network methods (PMeSNNr), with a three dimensional visualisation of relationships between variables is proposed. In brief, the architecture is able to transfer spatio-temporal data patterns from a multidimensional input stream into internal patterns in the spiking neural network reservoir. These patterns are then analysed to produce a personalised model for either classification or prediction dependent on the specific needs of the situation. The architecture described above was constructed using MatLab© in several individual modules linked together to form NeuCube (M1). This methodology has been applied to two real world case studies. Firstly, it has been applied to data for the prediction of stroke occurrences on an individual basis. Secondly, it has been applied to ecological data on aphid pest abundance prediction. Two main objectives for this research when judging outcomes of the modelling are accurate prediction and to have this at the earliest possible time point. The implications of these findings are not insignificant in terms of health care management and environmental control. As the case studies utilised here represent vastly different application fields, it reveals more of the potential and usefulness of NeuCube (M1) for modelling data in an integrated manner. This in turn can identify previously unknown (or less understood) interactions thus both increasing the level of reliance that can be placed on the model created, and enhancing our human understanding of the complexities of the world around us without the need for over simplification. Read less Keywords Personalised modelling; Spiking neural network; Spatial-temporal data modelling; Computational intelligence; Predictive modelling; Stroke risk predictio

Spatial-temporal data modelling and processing for personalised decision support

The purpose of this research is to undertake the modelling of dynamic data without losing any of the temporal relationships, and to be able to predict likelihood of outcome as far in advance of actual occurrence as possible. To this end a novel computational architecture for personalised ( individualised) modelling of spatio-temporal data based on spiking neural network methods (PMeSNNr), with a three dimensional visualisation of relationships between variables is proposed. In brief, the architecture is able to transfer spatio-temporal data patterns from a multidimensional input stream into internal patterns in the spiking neural network reservoir. These patterns are then analysed to produce a personalised model for either classification or prediction dependent on the specific needs of the situation. The architecture described above was constructed using MatLab© in several individual modules linked together to form NeuCube (M1). This methodology has been applied to two real world case studies. Firstly, it has been applied to data for the prediction of stroke occurrences on an individual basis. Secondly, it has been applied to ecological data on aphid pest abundance prediction. Two main objectives for this research when judging outcomes of the modelling are accurate prediction and to have this at the earliest possible time point. The implications of these findings are not insignificant in terms of health care management and environmental control. As the case studies utilised here represent vastly different application fields, it reveals more of the potential and usefulness of NeuCube (M1) for modelling data in an integrated manner. This in turn can identify previously unknown (or less understood) interactions thus both increasing the level of reliance that can be placed on the model created, and enhancing our human understanding of the complexities of the world around us without the need for over simplification. Read less Keywords Personalised modelling; Spiking neural network; Spatial-temporal data modelling; Computational intelligence; Predictive modelling; Stroke risk predictio

Intelligent systems in manufacturing: current developments and future prospects

Global competition and rapidly changing customer requirements are demanding increasing changes in manufacturing environments. Enterprises are required to constantly redesign their products and continuously reconfigure their manufacturing systems. Traditional approaches to manufacturing systems do not fully satisfy this new situation. Many authors have proposed that artificial intelligence will bring the flexibility and efficiency needed by manufacturing systems. This paper is a review of artificial intelligence techniques used in manufacturing systems. The paper first defines the components of a simplified intelligent manufacturing systems (IMS), the different Artificial Intelligence (AI) techniques to be considered and then shows how these AI techniques are used for the components of IMS

Survey on Combinatorial Register Allocation and Instruction Scheduling

Register allocation (mapping variables to processor registers or memory) and instruction scheduling (reordering instructions to increase instruction-level parallelism) are essential tasks for generating efficient assembly code in a compiler. In the last three decades, combinatorial optimization has emerged as an alternative to traditional, heuristic algorithms for these two tasks. Combinatorial optimization approaches can deliver optimal solutions according to a model, can precisely capture trade-offs between conflicting decisions, and are more flexible at the expense of increased compilation time. This paper provides an exhaustive literature review and a classification of combinatorial optimization approaches to register allocation and instruction scheduling, with a focus on the techniques that are most applied in this context: integer programming, constraint programming, partitioned Boolean quadratic programming, and enumeration. Researchers in compilers and combinatorial optimization can benefit from identifying developments, trends, and challenges in the area; compiler practitioners may discern opportunities and grasp the potential benefit of applying combinatorial optimization

QuASeR -- Quantum Accelerated De Novo DNA Sequence Reconstruction

In this article, we present QuASeR, a reference-free DNA sequence reconstruction implementation via de novo assembly on both gate-based and quantum annealing platforms. Each one of the four steps of the implementation (TSP, QUBO, Hamiltonians and QAOA) is explained with simple proof-of-concept examples to target both the genomics research community and quantum application developers in a self-contained manner. The details of the implementation are discussed for the various layers of the quantum full-stack accelerator design. We also highlight the limitations of current classical simulation and available quantum hardware systems. The implementation is open-source and can be found on https://github.com/prince-ph0en1x/QuASeR.Comment: 24 page

Computing Platforms for Big Biological Data Analytics: Perspectives and Challenges.

The last decade has witnessed an explosion in the amount of available biological sequence data, due to the rapid progress of high-throughput sequencing projects. However, the biological data amount is becoming so great that traditional data analysis platforms and methods can no longer meet the need to rapidly perform data analysis tasks in life sciences. As a result, both biologists and computer scientists are facing the challenge of gaining a profound insight into the deepest biological functions from big biological data. This in turn requires massive computational resources. Therefore, high performance computing (HPC) platforms are highly needed as well as efficient and scalable algorithms that can take advantage of these platforms. In this paper, we survey the state-of-the-art HPC platforms for big biological data analytics. We first list the characteristics of big biological data and popular computing platforms. Then we provide a taxonomy of different biological data analysis applications and a survey of the way they have been mapped onto various computing platforms. After that, we present a case study to compare the efficiency of different computing platforms for handling the classical biological sequence alignment problem. At last we discuss the open issues in big biological data analytics

A simheuristic algorithm for solving an integrated resource allocation and scheduling problem

Modern companies have to face challenging configuration issues in their manufacturing chains. One of these challenges is related to the integrated allocation and scheduling of resources such as machines, workers, energy, etc. These integrated optimization problems are difficult to solve, but they can be even more challenging when real-life uncertainty is considered. In this paper, we study an integrated allocation and scheduling optimization problem with stochastic processing times. A simheuristic algorithm is proposed in order to effectively solve this integrated and stochastic problem. Our approach relies on the hybridization of simulation with a metaheuristic to deal with the stochastic version of the allocation-scheduling problem. A series of numerical experiments contribute to illustrate the efficiency of our methodology as well as their potential applications in real-life enterprise settings